CPT® Code 0481T

1. Indications

The injection of autologous white blood cell concentrate is indicated for various conditions that benefit from enhanced healing and tissue regeneration. These include:

• Tendonitis - Inflammation of a tendon, often resulting from overuse or injury, which can cause pain and limit mobility.
• Bursitis - Inflammation of the bursa, a small fluid-filled sac that acts as a cushion between bones and soft tissues, leading to pain and swelling.
• Fasciitis - Inflammation of the fascia, the connective tissue surrounding muscles, which can result in pain and discomfort.
• Osteoarthritis - A degenerative joint disease characterized by the breakdown of cartilage, leading to pain, stiffness, and reduced joint function.
• Muscle injuries - Damage to muscle tissue that can occur due to acute trauma or chronic overuse.
• Ligament injuries - Injuries to the ligaments that connect bones at a joint, often resulting from sudden twists or impacts.
• Bone injuries - Fractures or other injuries to bone tissue that may benefit from enhanced healing through the use of autologous protein solution.

2. Procedure

The procedure for administering autologous white blood cell concentrate involves several critical steps to ensure safety and efficacy. First, blood is withdrawn from a peripheral vein, typically in the arm, using standard venipuncture techniques. This blood is then placed in a centrifuge or filtering machine, which separates the white blood cells and platelets from the red blood cells and serum. This separation process is essential for concentrating the components that promote healing. In some cases, additives may be mixed with the white blood cells and platelets to enhance their clotting and regenerative properties. Once the preparation is complete, the concentrated autologous protein solution is loaded into a sterile syringe, ready for injection. Prior to the injection, the skin over the target area is thoroughly cleaned and prepped to minimize the risk of infection. A local anesthetic may be administered to reduce discomfort during the procedure. Finally, the autologous protein solution is injected into the designated joint, tissue, or bone, often utilizing image guidance techniques such as ultrasound or fluoroscopy to ensure accurate placement and maximize the therapeutic effect.

3. Post-Procedure

After the injection of autologous white blood cell concentrate, patients may be monitored for any immediate adverse reactions. It is common for patients to experience some degree of soreness or swelling at the injection site, which typically resolves within a few days. Post-procedure care may include recommendations for rest and limited activity to allow the body to initiate its healing response. Patients are often advised to avoid strenuous activities for a specified period to prevent exacerbation of the treated area. Follow-up appointments may be scheduled to assess the effectiveness of the treatment and to determine if additional injections are necessary. Overall, the recovery process is individualized based on the specific condition being treated and the patient's overall health status.