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Official Description

Magnetic resonance spectroscopy, determination and localization of discogenic pain (cervical, thoracic, or lumbar); acquisition of single voxel data, per disc, on biomarkers (ie, lactic acid, carbohydrate, alanine, laal, propionic acid, proteoglycan, and collagen) in at least 3 discs

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

Magnetic resonance spectroscopy (MRS) is a sophisticated imaging technique that allows for the assessment of biochemical processes within the body, particularly in the context of spinal health. This procedure is specifically designed to identify and localize discogenic pain, which is pain originating from the intervertebral discs in the cervical, thoracic, or lumbar regions of the spine. By acquiring single voxel data from at least three discs, MRS can analyze various biomarkers that are indicative of disc health and degeneration. These biomarkers include lactic acid, carbohydrates, alanine, propionic acid, proteoglycan, and collagen, each of which plays a crucial role in understanding the biochemical environment of the discs. The significance of MRS lies in its ability to provide a noninvasive evaluation of disc integrity and the biochemical changes associated with pain. Chronic low back pain, a prevalent condition affecting millions globally, often leads to significant disability and is a common reason for opioid prescriptions. MRS helps in quantifying the degree of degeneration by measuring the concentrations of specific metabolites, which can inform treatment decisions and predict surgical outcomes. The technique leverages the unique resonant frequencies of different molecules when subjected to a strong magnetic field, allowing for the differentiation of various chemical structures. This detailed analysis aids in calculating the potential for pain based on the ratios of these biomarkers, thereby enhancing the understanding of disc disease severity and progression.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

Magnetic resonance spectroscopy (MRS) is indicated for the evaluation of discogenic pain, which may arise from degenerative changes in the intervertebral discs. The following conditions and symptoms may warrant the use of this procedure:

  • Chronic Low Back Pain Persistent pain in the lower back that may be associated with degenerative disc disease.
  • Cervical Pain Discomfort or pain in the neck region potentially linked to cervical disc degeneration.
  • Thoracic Pain Pain in the mid-back area that may be related to thoracic disc issues.
  • Disc Degeneration Assessment of the biochemical markers associated with the degeneration of intervertebral discs.

2. Procedure

The procedure for magnetic resonance spectroscopy involves several critical steps to ensure accurate data acquisition and analysis. The following outlines the procedural steps:

  • Step 1: Patient Preparation The patient is positioned appropriately on the MRI table, ensuring comfort and stability during the scanning process. The area of interest, typically the lumbar, thoracic, or cervical spine, is identified and marked for the procedure.
  • Step 2: Voxel Geometry Setup The scanner operator prescribes a single voxel geometry that encompasses the disc nucleus while excluding the vertebral body. This precise targeting is essential to obtain relevant data from the specific disc being evaluated.
  • Step 3: Data Acquisition The MRS scan is performed, during which a series of frames are acquired per disc. This step captures the biochemical information necessary for analysis, focusing on the biomarkers of interest.
  • Step 4: Data Transmission After the imaging data is collected, it is transmitted for customized post-processing. This step involves using specialized software to analyze the acquired data and extract meaningful insights regarding the biomarkers present in the discs.

3. Post-Procedure

Following the magnetic resonance spectroscopy procedure, patients may be monitored briefly to ensure there are no immediate adverse effects from the imaging process. The results of the MRS will be analyzed using specialized software, and the findings will be documented for further review. The interpretation of the data will provide insights into the biochemical status of the discs, which can inform treatment decisions and potential surgical interventions. Patients may be advised on follow-up appointments to discuss the results and any necessary next steps in their care plan.

Short Descr MRS DISC PAIN ACQUISJ DATA
Medium Descr MRS DISCOGENIC PAIN ACQUISJ SINGLE VOXEL DATA
Long Descr Magnetic resonance spectroscopy, determination and localization of discogenic pain (cervical, thoracic, or lumbar); acquisition of single voxel data, per disc, on biomarkers (ie, lactic acid, carbohydrate, alanine, laal, propionic acid, proteoglycan, and collagen) in at least 3 discs
Status Code Carriers Price the Code
Global Days YYY - Carrier Determines Whether Global Concept Applies
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Codes That May Be Paid Through a Composite APC
ASC Payment Indicator Radiology service paid separately when provided integral to a surgical procedure on ASC list; payment based on OPPS relative payment weight.
Berenson-Eggers TOS (BETOS) none
MUE 1
Date
Action
Notes
2021-01-01 Added First appearance of code in code book.
2020-07-01 Added Code added.
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