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Official Description

Fine needle aspiration biopsy, including ultrasound guidance; each additional lesion (List separately in addition to code for primary procedure)

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 10006 refers to a fine needle aspiration biopsy (FNA) that includes ultrasound guidance for each additional lesion. This procedure utilizes a fine gauge needle, typically 22- or 25-gauge, along with a syringe to extract fluid from a cyst or to collect clusters of cells from a solid mass. The process begins with the cleansing of the biopsy site, followed by the physician locating the lump through palpation. In cases where the lump is not palpable, imaging guidance, such as ultrasound, is employed to facilitate the FNA biopsy. For masses that are easier to locate, fluoroscopic guidance may also be utilized. Once the needle is accurately positioned within the mass, a vacuum is created, and the physician performs multiple in-and-out motions with the needle while pulling back on the syringe to ensure an adequate tissue sample is obtained. It is common for several needle insertions to be necessary to collect sufficient material for analysis. The collected samples are then prepared by smearing them onto a microscope slide, allowing them to air dry, and subsequently fixing them through spraying or immersion in a liquid. After fixation, the smears are stained and examined under a microscope by a pathologist for diagnostic purposes. Notably, FNA does not require stitches and is generally performed on an outpatient basis, allowing many patients to return to their normal activities on the same day. For billing purposes, code 10005 is reported for the first lesion biopsied by FNA with ultrasound guidance, while code 10006 is designated for each additional lesion biopsied in the same session.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The fine needle aspiration biopsy (FNA) procedure, as described by CPT® Code 10006, is indicated for various clinical scenarios where tissue sampling is necessary. The following conditions may warrant the use of this procedure:

  • Palpable Masses - When a lump or mass can be felt during a physical examination, FNA can be performed to obtain a tissue sample for diagnostic evaluation.
  • Non-Palpable Lesions - For lesions that cannot be felt, imaging guidance such as ultrasound is utilized to accurately locate and sample the tissue.
  • Cysts - FNA is often indicated for cystic structures to determine the nature of the fluid or cells within.
  • Solid Tumors - The procedure is also indicated for solid masses to collect cellular material for cytological analysis.

2. Procedure

The fine needle aspiration biopsy procedure involves several key steps to ensure accurate tissue sampling. The following outlines the procedural steps as per the CPT® guidelines:

  • Step 1: Preparation - The procedure begins with the patient being positioned comfortably, and the biopsy site is cleansed with an antiseptic solution to minimize the risk of infection.
  • Step 2: Localization - The physician locates the lump through palpation. If the lump is not palpable, ultrasound guidance is employed to visualize the lesion and guide the needle placement accurately.
  • Step 3: Needle Insertion - A fine gauge needle (22- or 25-gauge) is then inserted into the mass. The physician creates a vacuum by pulling back on the syringe while performing multiple in-and-out motions with the needle to collect the tissue sample.
  • Step 4: Sample Collection - Several needle insertions may be necessary to ensure that an adequate sample is obtained for analysis. The collected material is then prepared by smearing it onto a microscope slide.
  • Step 5: Fixation and Staining - The smears are allowed to air dry and are subsequently fixed using a spray or immersion in a liquid. After fixation, the samples are stained and prepared for microscopic examination by a pathologist.

3. Post-Procedure

After the fine needle aspiration biopsy is completed, the patient typically receives a small bandage over the biopsy site. The procedure is minimally invasive and does not require stitches, allowing for outpatient management. Most patients can resume their normal activities on the same day of the procedure. It is important for patients to monitor the biopsy site for any signs of complications, such as excessive bleeding or infection, and to follow any specific post-procedure care instructions provided by the healthcare provider.

Short Descr FNA BX W/US GDN EA ADDL
Medium Descr FINE NEEDLE ASPIRATION BX W/US GDN EA ADDL
Long Descr Fine needle aspiration biopsy, including ultrasound guidance; each additional lesion (List separately in addition to code for primary procedure)
Status Code Active Code
Global Days ZZZ - Code Related to Another Service
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Items and Services Packaged into APC Rates
ASC Payment Indicator Packaged service/item; no separate payment made.
Berenson-Eggers TOS (BETOS) none
MUE 3

This is an add-on code that must be used in conjunction with one of these primary codes.

10005 Resequenced Code MPFS Status: Active Code APC T ASC G2 Fine needle aspiration biopsy, including ultrasound guidance; first lesion
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
LT Left side (used to identify procedures performed on the left side of the body)
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
GC This service has been performed in part by a resident under the direction of a teaching physician
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
RT Right side (used to identify procedures performed on the right side of the body)
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
CR Catastrophe/disaster related
GA Waiver of liability statement issued as required by payer policy, individual case
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
99 Multiple modifiers: under certain circumstances 2 or more modifiers may be necessary to completely delineate a service. in such situations modifier 99 should be added to the basic procedure, and other applicable modifiers may be listed as part of the description of the service.
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
GW Service not related to the hospice patient's terminal condition
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
QJ Services/items provided to a prisoner or patient in state or local custody, however the state or local government, as applicable, meets the requirements in 42 cfr 411.4 (b)
TC Technical component; under certain circumstances, a charge may be made for the technical component alone; under those circumstances the technical component charge is identified by adding modifier 'tc' to the usual procedure number; technical component charges are institutional charges and not billed separately by physicians; however, portable x-ray suppliers only bill for technical component and should utilize modifier tc; the charge data from portable x-ray suppliers will then be used to build customary and prevailing profiles
X3 Episodic/broad services: for reporting services by clinicians who have broad responsibility for the comprehensive needs of the patient that is limited to a defined period and circumstance such as a hospitalization; reporting clinician service examples include but are not limited to the hospitalist's services rendered providing comprehensive and general care to a patient while admitted to the hospital
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
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