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Official Description

Excision, malignant lesion including margins, face, ears, eyelids, nose, lips; excised diameter 2.1 to 3.0 cm

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

A malignant lesion refers to an abnormal growth of cells that can invade surrounding tissues and potentially spread to other parts of the body. In the context of CPT® Code 11643, this procedure specifically involves the excision of such lesions located on the face, ears, eyelids, nose, lips, or mucous membranes. The excision is performed with the inclusion of a margin of normal tissue to ensure that all cancerous cells are removed, which is critical for preventing recurrence. Common types of malignant lesions that may be excised using this code include basal cell carcinoma, squamous cell carcinoma, verrucous carcinoma, and melanoma. The procedure begins with the cleansing of the area and the administration of a local anesthetic to minimize discomfort. A careful assessment is made to identify a margin of healthy tissue surrounding the lesion, and a full-thickness incision is executed through the dermis. The incision is designed to encircle the lesion, allowing for complete excision. In some cases, a frozen section may be performed during the excision to verify that the margins are clear of malignant cells. If any malignant tissue is detected at the margins, further excision is necessary until all margins are confirmed to be clean. The excised lesion is then sent for histologic evaluation to determine the nature of the tissue. To manage any bleeding that may occur during the procedure, electrocautery or chemical cautery techniques are employed. Finally, the surgical wound may be closed using a simple single-layer suture technique, although more complex closure methods such as intermediate (layer) closure, complex repair, skin grafts, or pedicle flaps may also be utilized depending on the specific circumstances of the excision.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure described by CPT® Code 11643 is indicated for the excision of malignant lesions located on the face, ears, eyelids, nose, lips, or mucous membranes. These lesions may include:

  • Basal Cell Carcinoma - A common type of skin cancer that arises from basal cells, often appearing as a pearly or waxy bump.
  • Squamous Cell Carcinoma - A type of skin cancer that originates from squamous cells, typically presenting as a firm, red nodule or a flat lesion with a scaly crust.
  • Verrucous Carcinoma - A variant of squamous cell carcinoma that is characterized by a warty appearance and is often found in the oral cavity or on the skin.
  • Melanoma - A serious form of skin cancer that develops from melanocytes, often appearing as a new or changing mole with irregular borders and multiple colors.

2. Procedure

The procedure for excising a malignant lesion as described by CPT® Code 11643 involves several critical steps:

  • Step 1: Preparation - The area surrounding the malignant lesion is thoroughly cleansed to reduce the risk of infection. A local anesthetic is then injected to ensure the patient remains comfortable throughout the procedure.
  • Step 2: Identification of Margins - The surgeon carefully identifies a margin of healthy tissue surrounding the lesion. This margin is essential to ensure that all cancerous cells are removed during the excision.
  • Step 3: Incision - A full-thickness incision is made through the dermis, encircling the lesion. This incision is designed to remove the lesion along with the identified margin of healthy tissue.
  • Step 4: Excision - The entire lesion, along with the surrounding healthy tissue, is excised. This step is crucial for ensuring that no malignant cells remain.
  • Step 5: Frozen Section Analysis - If necessary, a frozen section may be performed at this stage to evaluate the margins for any remaining malignant cells. If malignant tissue is detected, additional excision is performed until clear margins are achieved.
  • Step 6: Histologic Evaluation - The excised lesion is sent to the laboratory for histologic evaluation, which is separately reportable, to confirm the diagnosis and assess the nature of the tissue.
  • Step 7: Hemostasis - Any bleeding that occurs during the procedure is controlled using electrocautery or chemical cautery techniques to minimize blood loss.
  • Step 8: Wound Closure - The surgical wound may be closed using a simple single-layer suture technique. Depending on the complexity of the excision, other closure methods such as intermediate (layer) closure, complex repair, skin grafts, or pedicle flaps may also be employed.

3. Post-Procedure

After the excision procedure, patients are typically monitored for any immediate complications. Post-procedure care may include instructions on wound care to promote healing and prevent infection. Patients may be advised to keep the area clean and dry, and to follow up with their healthcare provider for suture removal or further evaluation as needed. The expected recovery time can vary based on the size and location of the excised lesion, as well as the method of closure used. It is important for patients to report any signs of infection, increased pain, or unusual changes in the wound to their healthcare provider promptly.

Short Descr EXC F/E/E/N/L MAL+MRG 2.1-3
Medium Descr EXCISION MALIGNANT LESION F/E/E/N/L 2.1-3.0 CM
Long Descr Excision, malignant lesion including margins, face, ears, eyelids, nose, lips; excised diameter 2.1 to 3.0 cm
Status Code Active Code
Global Days 010 - Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Office-based surgical procedure added to ASC list in CY 2008 or later with MPFS nonfacility PE RVUs; payment based on MPFS nonfacility PE RVUs.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P5A - Ambulatory procedures - skin
MUE 2
CCS Clinical Classification 170 - Excision of skin lesion
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
LT Left side (used to identify procedures performed on the left side of the body)
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
GC This service has been performed in part by a resident under the direction of a teaching physician
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
AG Primary physician
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
CG Policy criteria applied
CR Catastrophe/disaster related
E1 Upper left, eyelid
E2 Lower left, eyelid
E3 Upper right, eyelid
E4 Lower right, eyelid
GA Waiver of liability statement issued as required by payer policy, individual case
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
GZ Item or service expected to be denied as not reasonable and necessary
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
RT Right side (used to identify procedures performed on the right side of the body)
SG Ambulatory surgical center (asc) facility service
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XP Separate practitioner, a service that is distinct because it was performed by a different practitioner
Date
Action
Notes
2013-01-01 Changed Medium Descriptor changed.
2003-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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