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Official Description

Subcutaneous hormone pellet implantation (implantation of estradiol and/or testosterone pellets beneath the skin)

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

Subcutaneous hormone pellet implantation, identified by CPT® Code 11980, involves the surgical placement of hormone pellets beneath the skin. These pellets are typically composed of estradiol and/or testosterone, which are hormones essential for various bodily functions. The procedure is primarily utilized for hormone replacement therapy, aimed at alleviating symptoms associated with hormonal deficiencies or imbalances. The implantation process allows for a slow and continuous release of these hormones into the bloodstream, providing a stable therapeutic effect over time. This method is often preferred due to its convenience and the sustained release of hormones, which can enhance patient compliance compared to daily or weekly dosing regimens. The procedure is performed under local anesthesia, ensuring that the patient remains comfortable while minimizing discomfort during the implantation. Following the insertion of the pellets, pressure is applied to the site to control any bleeding, and adhesive strips are used to secure the incision, promoting proper healing. Typically, new hormone pellets are implanted every six months to maintain effective hormone levels in the body.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The subcutaneous hormone pellet implantation procedure is indicated for patients experiencing hormonal deficiencies or imbalances that may benefit from hormone replacement therapy. The following conditions may warrant this procedure:

  • Hormonal Deficiency Patients with low levels of estradiol or testosterone, which can lead to various symptoms such as fatigue, mood swings, and decreased libido.
  • Menopausal Symptoms Women undergoing menopause may experience symptoms like hot flashes, night sweats, and vaginal dryness, which can be alleviated through hormone replacement.
  • Andropause Symptoms Men may experience symptoms related to andropause, including reduced energy levels, mood changes, and decreased sexual function, which can be addressed with testosterone therapy.

2. Procedure

The procedure for subcutaneous hormone pellet implantation involves several key steps to ensure proper placement and patient safety.

  • Step 1: Preparation The patient is positioned comfortably, and the area where the pellets will be implanted is cleaned and sterilized to minimize the risk of infection. Local anesthesia is administered to numb the site, ensuring the patient experiences minimal discomfort during the procedure.
  • Step 2: Incision A small incision is made in the skin, typically in a discreet location to enhance cosmetic outcomes. This incision is just large enough to allow for the insertion of the hormone pellets.
  • Step 3: Pellet Insertion The hormone pellets, which contain either estradiol or testosterone, are carefully inserted into the subcutaneous tissue through the incision. The number of pellets used may vary based on the patient's specific hormonal needs and treatment plan.
  • Step 4: Wound Closure After the pellets are placed, pressure is applied to the site to control any bleeding. The incision is then closed using adhesive strips, which help to secure the skin and promote healing without the need for stitches.
  • Step 5: Post-Procedure Care The patient is monitored briefly to ensure there are no immediate complications. Instructions for post-procedure care are provided, including how to care for the incision site and when to schedule follow-up appointments for future pellet insertions.

3. Post-Procedure

After the subcutaneous hormone pellet implantation, patients are advised to follow specific post-procedure care instructions to ensure proper healing and minimize the risk of complications. It is common for patients to experience some swelling or tenderness at the implantation site, which typically resolves within a few days. Patients should keep the area clean and dry, avoiding any strenuous activities that may strain the incision site for a short period. Follow-up appointments are usually scheduled every six months to assess hormone levels and determine the need for additional pellet insertions. Patients are encouraged to report any unusual symptoms or signs of infection, such as increased redness, swelling, or discharge from the incision site, to their healthcare provider promptly.

Short Descr IMPLANT HORMONE PELLET(S)
Medium Descr SUBCUTANEOUS HORMONE PELLET IMPLANTATION
Long Descr Subcutaneous hormone pellet implantation (implantation of estradiol and/or testosterone pellets beneath the skin)
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator STV-Packaged Codes
ASC Payment Indicator Packaged service/item; no separate payment made.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P6A - Minor procedures - skin
MUE 1
CCS Clinical Classification 231 - Other therapeutic procedures
GA Waiver of liability statement issued as required by payer policy, individual case
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
GZ Item or service expected to be denied as not reasonable and necessary
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
CR Catastrophe/disaster related
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
GC This service has been performed in part by a resident under the direction of a teaching physician
GX Notice of liability issued, voluntary under payer policy
JZ Zero drug amount discarded/not administered to any patient
KX Requirements specified in the medical policy have been met
LT Left side (used to identify procedures performed on the left side of the body)
PD Diagnostic or related non diagnostic item or service provided in a wholly owned or operated entity to a patient who is admitted as an inpatient within 3 days
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
RT Right side (used to identify procedures performed on the right side of the body)
SA Nurse practitioner rendering service in collaboration with a physician
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
2000-01-01 Added First appearance in code book in 2000.
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