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Official Description

Biopsy, bone, open; superficial (eg, sternum, spinous process, rib, patella, olecranon process, calcaneus, tarsal, metatarsal, carpal, metacarpal, phalanx)

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

An open bone biopsy is a surgical procedure that involves the removal of a small sample of bone tissue for pathological examination. This procedure is typically performed under either regional block or general anesthesia to ensure the patient's comfort. The primary purpose of an open bone biopsy is to obtain a definitive diagnosis regarding various bone conditions. It is particularly useful in evaluating persistent bone pain or tenderness, confirming diagnoses suggested by other diagnostic tests, and investigating abnormalities detected through radiologic imaging. Additionally, this procedure helps differentiate between benign bone masses and malignant conditions such as bone cancer. It is also instrumental in diagnosing bone diseases or infections, including osteoporosis, osteomalacia, and osteomyelitis. During the procedure, a skin incision is made directly over the targeted area of the bone, and the incision is extended through the subcutaneous tissue and muscle until the bone is reached. A small segment of bone is then excised and sent to a laboratory for further analysis. To manage bleeding, any blood vessels encountered during the procedure are either tied off or cauterized. After the bone sample is collected, the surgical site is thoroughly cleansed, and the incision is sutured closed and bandaged to promote healing. The specific CPT® code for this procedure is 20240, which pertains to the open biopsy of superficial bones, including structures such as the sternum, spinous process, rib, patella, olecranon process, calcaneus, tarsal, metatarsal, carpal, metacarpal, and phalanx. For open biopsies of deeper bone structures, such as the humeral shaft, ischium, and femoral shaft, the appropriate code is 20245.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The open bone biopsy procedure is indicated for several specific clinical scenarios, including:

  • Bone Pain or Tenderness - Persistent or unexplained bone pain or tenderness that requires further investigation.
  • Confirmation of Diagnosis - Situations where a diagnosis suggested by other tests needs to be confirmed through direct tissue analysis.
  • Radiologic Abnormalities - Abnormal findings on radiologic scans that necessitate further evaluation to determine their nature.
  • Benign vs. Malignant Masses - Differentiating between benign bone masses and malignant conditions, such as bone cancer.
  • Bone Disease or Infection - Diagnosing conditions such as osteoporosis, osteomalacia, and osteomyelitis that affect bone health.

2. Procedure

The open bone biopsy procedure involves several critical steps to ensure successful tissue acquisition and patient safety:

  • Step 1: Anesthesia Administration - The procedure begins with the administration of either regional block or general anesthesia to ensure the patient is comfortable and pain-free during the surgery.
  • Step 2: Incision Creation - A skin incision is made over the targeted biopsy site. This incision is carefully extended through the subcutaneous tissue and muscle layers to reach the bone.
  • Step 3: Bone Sample Removal - Once the bone is exposed, a small segment of bone is excised using appropriate surgical instruments. This sample is critical for subsequent pathological analysis.
  • Step 4: Hemostasis - During the procedure, any blood vessels that are encountered are either tied off or cauterized to control bleeding and minimize complications.
  • Step 5: Wound Closure - After the bone sample has been collected, the surgical site is thoroughly cleansed to reduce the risk of infection. The incision is then sutured closed, and a bandage is applied to protect the area.

3. Post-Procedure

After the open bone biopsy, patients are typically monitored for any immediate complications related to the procedure. Post-procedure care may include instructions for wound care, pain management, and activity restrictions to promote healing. Patients may be advised to avoid strenuous activities for a specified period to allow the surgical site to recover properly. Follow-up appointments may be scheduled to discuss the results of the biopsy and any further treatment options based on the findings.

Short Descr BONE BIOPSY OPEN SUPERFICIAL
Medium Descr BIOPSY BONE OPEN SUPERFICIAL
Long Descr Biopsy, bone, open; superficial (eg, sternum, spinous process, rib, patella, olecranon process, calcaneus, tarsal, metatarsal, carpal, metacarpal, phalanx)
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P5B - Ambulatory procedures - musculoskeletal
MUE 4
CCS Clinical Classification 159 - Other diagnostic procedures on musculoskeletal system

This is a primary code that can be used with these additional add-on codes.

20700 Add-on Code MPFS Status: Active Code APC N ASC N1 Manual preparation and insertion of drug-delivery device(s), deep (eg, subfascial) (List separately in addition to code for primary procedure)
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
RT Right side (used to identify procedures performed on the right side of the body)
LT Left side (used to identify procedures performed on the left side of the body)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
47 Anesthesia by surgeon: regional or general anesthesia provided by the surgeon may be reported by adding modifier 47 to the basic service. (this does not include local anesthesia.) note: modifier 47 would not be used as a modifier for the anesthesia procedures.
GC This service has been performed in part by a resident under the direction of a teaching physician
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
81 Minimum assistant surgeon: minimum surgical assistant services are identified by adding modifier 81 to the usual procedure number.
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
CR Catastrophe/disaster related
F1 Left hand, second digit
F2 Left hand, third digit
F3 Left hand, fourth digit
F4 Left hand, fifth digit
F5 Right hand, thumb
F6 Right hand, second digit
F7 Right hand, third digit
F8 Right hand, fourth digit
FA Left hand, thumb
GA Waiver of liability statement issued as required by payer policy, individual case
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
GX Notice of liability issued, voluntary under payer policy
KX Requirements specified in the medical policy have been met
MG The order for this service does not have applicable appropriate use criteria in the qualified clinical decision support mechanism consulted by the ordering professional
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
SG Ambulatory surgical center (asc) facility service
T1 Left foot, second digit
T2 Left foot, third digit
T3 Left foot, fourth digit
T4 Left foot, fifth digit
T5 Right foot, great toe
T6 Right foot, second digit
T7 Right foot, third digit
T8 Right foot, fourth digit
T9 Right foot, fifth digit
TA Left foot, great toe
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
2017-01-01 Changed Long and Short descriptions changed.
2011-01-01 Changed Short description changed.
2004-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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