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Official Description

Excision, tumor, soft tissue of neck or anterior thorax, subfascial (eg, intramuscular); less than 5 cm

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 21556 refers to the excision of a tumor located in the soft tissue of the neck or anterior thorax, specifically when the tumor is subfascial, meaning it lies beneath the fascia, which is a layer of connective tissue. This procedure is applicable for tumors that measure less than 5 cm in size. Soft tissues encompass a variety of structures, including subcutaneous fat, connective tissue, fascia, muscles, tendons, blood vessels, lymph vessels, nerves, and the tissues surrounding joints. Tumors found in these soft tissues can be either benign or malignant. Typically, benign tumors are removed through excision, while small malignant or indeterminate tumors may also be excised if they have well-defined margins. The surgical approach to excising these tumors may vary based on their location; it may involve incising the skin directly over the tumor, creating and elevating a skin flap, or making a series of incisions along natural skin creases to facilitate exposure of the tumor. Once the tumor is accessed, the surrounding tissue is carefully dissected to expose the soft tissue mass, which is then excised along with a margin of healthy tissue to ensure complete removal. In some cases, a frozen section may be performed to verify that the margins are free of tumor cells, which is a separate reportable procedure. After the excision, drains may be placed as necessary, and the surgical wound is typically closed in layers to promote proper healing. For tumors located in the subcutaneous fat or connective tissue, different codes are used based on the size of the mass, with CPT® Code 21555 designated for masses less than 3 cm and CPT® Code 21552 for those 3 cm or greater. For subfascial tumors, CPT® Code 21556 is specifically used for masses less than 5 cm, while CPT® Code 21554 is reserved for those measuring 5 cm or greater. It is important to note that subfascial soft tissue tumors include those situated within muscle tissue.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The excision of a tumor in the soft tissue of the neck or anterior thorax, as described by CPT® Code 21556, is indicated for the following conditions:

  • Soft Tissue Tumors Tumors located in the soft tissues of the neck or anterior thorax that may be benign or malignant.
  • Well-Defined Margins Small malignant or indeterminate tumors that have well-defined margins, making them suitable for excision.
  • Size Criteria Tumors that are subfascial and measure less than 5 cm in size.

2. Procedure

The procedure for excising a subfascial tumor in the soft tissue of the neck or anterior thorax involves several key steps:

  • Incision The surgeon begins by making an incision in the skin over the tumor. Depending on the tumor's location, this may involve creating a skin flap or making incisions along natural skin creases to minimize scarring and facilitate access.
  • Tissue Dissection Once the incision is made, the overlying tissue is carefully dissected to expose the soft tissue mass. This dissection is performed with precision to avoid damaging surrounding structures such as nerves and blood vessels.
  • Excision of Tumor After the tumor is fully exposed, it is excised along with a margin of healthy tissue. This margin is critical to ensure that any potential cancerous cells are removed, reducing the risk of recurrence.
  • Frozen Section Analysis In some cases, a frozen section may be performed during the procedure. This involves taking a small sample of the excised tissue and rapidly processing it to check for the presence of tumor cells at the margins. This step is crucial for confirming that the excision is complete.
  • Placement of Drains If necessary, drains may be placed to prevent fluid accumulation at the surgical site, which can aid in the healing process.
  • Closure of Wound Finally, the surgical wound is closed in layers. This layered closure technique helps to promote optimal healing and reduces the risk of complications such as infection or dehiscence.

3. Post-Procedure

After the excision of the tumor, patients may require specific post-procedure care to ensure proper recovery. This may include monitoring for signs of infection, managing pain, and following up with the healthcare provider for wound assessment. Patients are typically advised on activity restrictions to allow the surgical site to heal adequately. Additionally, if a frozen section was performed, the results will guide any further treatment decisions, especially if malignancy is confirmed. Follow-up appointments are essential to monitor the surgical site and assess for any recurrence of the tumor.

Short Descr EXC NECK TUM DEEP < 5 CM
Medium Descr EXC TUMOR SOFT TISS NECK/THORAX SUBFASCIAL <5CM
Long Descr Excision, tumor, soft tissue of neck or anterior thorax, subfascial (eg, intramuscular); less than 5 cm
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Non office-based surgical procedure added in CY 2008 or later; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P5B - Ambulatory procedures - musculoskeletal
MUE 2
CCS Clinical Classification 160 - Other therapeutic procedures on muscles and tendons
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
62 Two surgeons: when 2 surgeons work together as primary surgeons performing distinct part(s) of a procedure, each surgeon should report his/her distinct operative work by adding modifier 62 to the procedure code and any associated add-on code(s) for that procedure as long as both surgeons continue to work together as primary surgeons. each surgeon should report the co-surgery once using the same procedure code. if additional procedure(s) (including add-on procedure(s) are performed during the same surgical session, separate code(s) may also be reported with modifier 62 added. note: if a co-surgeon acts as an assistant in the performance of additional procedure(s), other than those reported with the modifier 62, during the same surgical session, those services may be reported using separate procedure code(s) with modifier 80 or modifier 82 added, as appropriate.
74 Discontinued out-patient hospital/ambulatory surgery center (asc) procedure after administration of anesthesia: due to extenuating circumstances or those that threaten the well being of the patient, the physician may terminate a surgical or diagnostic procedure after the administration of anesthesia (local, regional block(s), general) or after the procedure was started (incision made, intubation started, scope inserted, etc). under these circumstances, the procedure started but terminated can be reported by its usual procedure number and the addition of modifier 74. note: the elective cancellation of a service prior to the administration of anesthesia and/or surgical preparation of the patient should not be reported. for physician reporting of a discontinued procedure, see modifier 53.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
AG Primary physician
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CR Catastrophe/disaster related
GA Waiver of liability statement issued as required by payer policy, individual case
GC This service has been performed in part by a resident under the direction of a teaching physician
GW Service not related to the hospice patient's terminal condition
LT Left side (used to identify procedures performed on the left side of the body)
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
RT Right side (used to identify procedures performed on the right side of the body)
SG Ambulatory surgical center (asc) facility service
X3 Episodic/broad services: for reporting services by clinicians who have broad responsibility for the comprehensive needs of the patient that is limited to a defined period and circumstance such as a hospitalization; reporting clinician service examples include but are not limited to the hospitalist's services rendered providing comprehensive and general care to a patient while admitted to the hospital
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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2010-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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