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Official Description

Percutaneous vertebroplasty (bone biopsy included when performed), 1 vertebral body, unilateral or bilateral injection, inclusive of all imaging guidance; lumbosacral

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

Percutaneous vertebroplasty is a minimally invasive procedure designed to stabilize compression fractures in the spine, particularly those caused by osteoporosis. This procedure is also applicable for treating aggressive hemangiomas of the vertebral body and for providing palliative care for pathological fractures resulting from benign or malignant tumors in the spinal region. During the procedure, the patient is positioned prone, allowing the physician to access the affected vertebral body effectively. Imaging guidance, such as fluoroscopy or computed tomography (CT), is utilized to accurately identify the vertebral level that requires intervention. Local anesthesia is administered to ensure patient comfort throughout the procedure. A spinal needle is then carefully advanced into the vertebral body, and additional local anesthesia is applied to the surrounding tissues. If a biopsy is indicated, a small incision is made to facilitate the insertion of a bone biopsy needle, which is used to obtain a sample of the vertebral body for pathological examination. Following the biopsy, the vertebroplasty is performed by injecting a mixture of polymethylmethacrylate (PMMA) bone cement and a contrast medium into the vertebral body. This cement serves to reinforce the structure of the fractured vertebra, with the contrast medium allowing for visualization of the cement distribution within the bone marrow space. The procedure can be performed unilaterally or bilaterally, depending on the specific clinical scenario, with the option for a second injection on the opposite side of the vertebral body for bilateral repairs. This comprehensive approach ensures effective stabilization of the vertebral body and alleviation of pain associated with spinal fractures.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure of percutaneous vertebroplasty is indicated for the following conditions:

  • Compression Fractures Stabilization of compression fractures caused by osteoporosis of the spine.
  • Aggressive Hemangiomas Treatment of aggressive hemangiomas located in the vertebral body.
  • Palliative Treatment Management of pathological fractures due to benign or malignant neoplasms of the spine.

2. Procedure

The percutaneous vertebroplasty procedure involves several key steps to ensure effective treatment of the affected vertebral body:

  • Patient Positioning The patient is placed in a prone position to allow optimal access to the spine for the procedure.
  • Imaging Guidance Fluoroscopic or CT imaging is utilized to accurately identify the specific vertebral level that requires intervention, ensuring precision in the procedure.
  • Administration of Local Anesthesia Local anesthesia is administered to the patient to minimize discomfort during the procedure.
  • Needle Insertion A spinal needle is advanced into one side of the vertebral body. Deep local and subperiosteal anesthesia is also administered to enhance patient comfort.
  • Bone Biopsy (if needed) If a biopsy is indicated, a small incision is made in the skin, and a bone biopsy needle is advanced into the vertebral body to obtain a bone sample, which is then sent for pathological examination.
  • Injection of Bone Cement The vertebroplasty is performed by injecting a mixture of polymethylmethacrylate (PMMA) bone cement and a contrast medium into the vertebral body. The contrast medium, such as sterile barium or tungsten powder, allows for visualization of the cement as it diffuses throughout the intertrabecular bone marrow space.
  • Observation of Cement Distribution The physician observes the distribution of the bone cement within the vertebral body to ensure adequate reinforcement of the fractured structure.
  • Needle Withdrawal After the injection, the spinal needle is withdrawn from the vertebral body.
  • Bilateral Injection (if applicable) For bilateral repair procedures, a second injection is performed on the opposite side of the vertebral body to complete the stabilization process.

3. Post-Procedure

Post-procedure care for patients undergoing percutaneous vertebroplasty typically includes monitoring for any immediate complications and assessing the patient's pain levels. Patients may be advised to rest and avoid strenuous activities for a specified period following the procedure. Follow-up appointments may be scheduled to evaluate the effectiveness of the treatment and to monitor the healing process. Additionally, any biopsy samples obtained during the procedure will be analyzed, and results will be discussed with the patient in subsequent visits.

Short Descr PERQ LUMBOSACRAL INJECTION
Medium Descr PERQ VERTEBROPLASTY UNI/BI INJECTION LUMBOSACRAL
Long Descr Percutaneous vertebroplasty (bone biopsy included when performed), 1 vertebral body, unilateral or bilateral injection, inclusive of all imaging guidance; lumbosacral
Status Code Active Code
Global Days 010 - Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Non office-based surgical procedure added in CY 2008 or later; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P1G - Major procedure - Other
MUE 1

This is a primary code that can be used with these additional add-on codes.

22512 Addon Code MPFS Status: Active Code APC N ASC N1 Percutaneous vertebroplasty (bone biopsy included when performed), 1 vertebral body, unilateral or bilateral injection, inclusive of all imaging guidance; each additional cervicothoracic or lumbosacral vertebral body (List separately in addition to code for primary procedure)
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
GZ Item or service expected to be denied as not reasonable and necessary
GC This service has been performed in part by a resident under the direction of a teaching physician
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
AG Primary physician
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
CR Catastrophe/disaster related
GA Waiver of liability statement issued as required by payer policy, individual case
GW Service not related to the hospice patient's terminal condition
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
LT Left side (used to identify procedures performed on the left side of the body)
MG The order for this service does not have applicable appropriate use criteria in the qualified clinical decision support mechanism consulted by the ordering professional
Q0 Investigational clinical service provided in a clinical research study that is in an approved clinical research study
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
RT Right side (used to identify procedures performed on the right side of the body)
SG Ambulatory surgical center (asc) facility service
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
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Notes
2017-01-01 Changed Moderate (Conscious) Sedation flag removed. See new Moderate Sedation category.
2015-01-01 Added Added
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