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Official Description

Removal of permanent pacemaker pulse generator with replacement of pacemaker pulse generator; dual lead system

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 33228 involves the removal of a permanent pacemaker pulse generator and the subsequent replacement with a new pulse generator specifically designed for a dual lead system. A permanent pacemaker is a medical device implanted in patients to help regulate heart rhythms, particularly in cases of bradycardia or other heart rhythm disorders. The removal of the pulse generator is typically necessitated by issues such as malfunctioning of the device or the depletion of the generator's battery life. During this procedure, a surgical incision is made over the site of the existing pulse generator, allowing access to the skin pocket where the device is housed. The electrodes connected to the pacemaker are carefully disconnected, and the generator is meticulously dissected from the surrounding tissue to ensure minimal trauma. Following the removal, a new pulse generator is attached to the existing leads, and its functionality is tested to confirm proper operation. Once verified, the new generator is positioned back into the pocket, secured to the underlying tissue, and the incision is closed. This procedure is critical for maintaining the effective management of a patient's cardiac condition, ensuring that the pacing system continues to function optimally.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 33228 is indicated for patients who require the replacement of a malfunctioning or depleted permanent pacemaker pulse generator in a dual lead system. The specific indications for this procedure include:

  • Malfunction of the existing pulse generator - This may manifest as irregular pacing, failure to capture, or other operational issues that compromise the device's effectiveness.
  • Battery depletion - When the battery of the pulse generator approaches its end of life, replacement is necessary to ensure continued cardiac pacing.
  • Patient symptoms - Patients may present with symptoms related to inadequate pacing, such as fatigue, dizziness, or syncope, prompting the need for generator replacement.

2. Procedure

The procedure for CPT® Code 33228 involves several critical steps to ensure the safe and effective replacement of the pacemaker pulse generator. The steps are as follows:

  • Step 1: Incision and Access - A surgical incision is made in the skin over the existing pulse generator site. This incision allows the surgeon to access the skin pocket where the pulse generator is located.
  • Step 2: Opening the Skin Pocket - The skin pocket is carefully opened to expose the pulse generator. This step requires precision to minimize damage to surrounding tissues.
  • Step 3: Disconnecting Electrodes - The electrodes connected to the existing pulse generator are disconnected. This step is crucial to ensure that the old generator can be safely removed without affecting the leads.
  • Step 4: Removal of the Old Generator - The pulse generator is dissected free from the surrounding tissue and removed from the pocket. Care is taken to avoid injury to the leads and surrounding structures.
  • Step 5: Testing the New Generator - The new pulse generator is attached to the existing lead(s) and tested to confirm that it is functioning correctly. This testing is essential to ensure that the pacing system will operate as intended.
  • Step 6: Placement of the New Generator - Once the new pulse generator is confirmed to be working properly, it is placed into the pocket. The generator is then sutured to the underlying tissue to secure it in place.
  • Step 7: Closing the Pocket - Finally, the skin pocket is closed, completing the procedure. Proper closure is important to promote healing and reduce the risk of infection.

3. Post-Procedure

After the completion of the procedure associated with CPT® Code 33228, patients typically require monitoring to ensure that the new pulse generator is functioning correctly and that there are no immediate complications. Post-procedure care may include pain management, wound care instructions, and follow-up appointments to assess the device's performance. Patients are often advised to avoid strenuous activities for a specified period to allow for proper healing. Additionally, they may need to be educated on recognizing signs of potential complications, such as infection or device malfunction, and when to seek medical attention.

Short Descr REMV&REPLC PM GEN DUAL LEAD
Medium Descr REMVL PERM PM PLS GEN W/REPL PLSE GEN 2 LEAD SYS
Long Descr Removal of permanent pacemaker pulse generator with replacement of pacemaker pulse generator; dual lead system
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Device-intensive procedure added to ASC list in CY 2008 or later; paid at adjusted rate.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P2E - Major procedure, cardiovascular-Pacemaker insertion
MUE 1
CCS Clinical Classification 48 - Insertion, revision, replacement, removal of cardiac pacemaker or cardioverter/defibrillator

This is a primary code that can be used with these additional add-on codes.

33225 Addon Code MPFS Status: Active Code APC N ASC N1 Physician Quality Reporting PUB 100 CPT Assistant Article Insertion of pacing electrode, cardiac venous system, for left ventricular pacing, at time of insertion of implantable defibrillator or pacemaker pulse generator (eg, for upgrade to dual chamber system) (List separately in addition to code for primary procedure)
KX Requirements specified in the medical policy have been met
GC This service has been performed in part by a resident under the direction of a teaching physician
SC Medically necessary service or supply
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
AO Alternate payment method declined by provider of service
CR Catastrophe/disaster related
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
GW Service not related to the hospice patient's terminal condition
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
54 Surgical care only: when 1 physician or other qualified health care professional performs a surgical procedure and another provides preoperative and/or postoperative management, surgical services may be identified by adding modifier 54 to the usual procedure number.
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
74 Discontinued out-patient hospital/ambulatory surgery center (asc) procedure after administration of anesthesia: due to extenuating circumstances or those that threaten the well being of the patient, the physician may terminate a surgical or diagnostic procedure after the administration of anesthesia (local, regional block(s), general) or after the procedure was started (incision made, intubation started, scope inserted, etc). under these circumstances, the procedure started but terminated can be reported by its usual procedure number and the addition of modifier 74. note: the elective cancellation of a service prior to the administration of anesthesia and/or surgical preparation of the patient should not be reported. for physician reporting of a discontinued procedure, see modifier 53.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
AG Primary physician
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
ET Emergency services
GA Waiver of liability statement issued as required by payer policy, individual case
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GZ Item or service expected to be denied as not reasonable and necessary
KK Dmepos item subject to dmepos competitive bidding program number 2
LT Left side (used to identify procedures performed on the left side of the body)
PD Diagnostic or related non diagnostic item or service provided in a wholly owned or operated entity to a patient who is admitted as an inpatient within 3 days
Q5 Service furnished under a reciprocal billing arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
SG Ambulatory surgical center (asc) facility service
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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2017-01-01 Changed Moderate (Conscious) Sedation flag removed. See new Moderate Sedation category.
2012-01-01 Added Added
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