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Official Description

Direct repair of aneurysm, pseudoaneurysm, or excision (partial or total) and graft insertion, with or without patch graft; for aneurysm, pseudoaneurysm, and associated occlusive disease, hepatic, celiac, renal, or mesenteric artery

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 35121 refers to the surgical procedure involving the direct repair of an aneurysm or pseudoaneurysm, as well as the excision (either partial or total) and graft insertion, which may include the use of a patch graft. This procedure specifically targets aneurysms, pseudoaneurysms, and any associated occlusive disease affecting the hepatic, celiac, renal, or mesenteric arteries. An aneurysm is characterized by an abnormal enlargement or dilation of an artery, which can arise from various causes such as arteriosclerosis, mechanical obstruction, or malposition of the artery. Less frequently, conditions like syphilis, tuberculosis, or abnormalities in the vessel wall, such as fibromuscular dysplasia, may also lead to aneurysm formation. In contrast, a pseudoaneurysm is defined as a hematoma that forms in direct communication with the artery wall but does not involve all three layers of the arterial wall, distinguishing it from a true aneurysm. Pseudoaneurysms often result from trauma—either blunt or penetrating—or complications from medical procedures, such as catheterization. Specific conditions, such as pancreatitis, septic emboli, or arteritis, can also contribute to the development of a pseudoaneurysm, particularly in the splenic artery. The celiac artery, which supplies blood to the liver, stomach, and spleen, branches off the abdominal aorta just below the diaphragm. The hepatic artery is a branch of the celiac trunk, while the renal arteries and the superior and inferior mesenteric arteries are additional visceral branches of the aorta. The surgical procedure described by CPT® Code 35121 is performed in a nonemergent, elective setting, contrasting with CPT® Code 35122, which pertains to the emergency repair of a ruptured aneurysm. The detailed surgical steps involved in this procedure include accessing the affected artery, establishing control over blood flow, and performing the necessary repairs or graft insertions to restore normal arterial function.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure described by CPT® Code 35121 is indicated for the surgical repair of the following conditions:

  • Aneurysm - An abnormal enlargement or dilation of an artery, which may be caused by various factors including arteriosclerosis or mechanical obstruction.
  • Pseudoaneurysm - A hematoma that forms in direct communication with the artery wall, typically resulting from trauma or complications from medical procedures.
  • Associated Occlusive Disease - Conditions that lead to blockage or narrowing of the arteries, affecting blood flow to the hepatic, celiac, renal, or mesenteric arteries.

2. Procedure

The procedure for CPT® Code 35121 involves several critical steps to ensure the successful repair of the aneurysm or pseudoaneurysm:

  • Step 1: Preparation and Incision - The patient is positioned appropriately, and the lower leg is prepped if a saphenous vein graft is to be harvested. A midline abdominal, transverse, or retroperitoneal flank incision is made to access the affected artery, typically the splenic artery.
  • Step 2: Exposure and Control - The overlying soft tissues are carefully divided to expose the aorta. The duodenum is dissected off the aorta to provide clear access. Proximal control is established above the celiac arteries, and distal control is established above the iliac arteries. Supraceliac aortic control is achieved by dividing ligaments to the left lateral segment of the liver and retracting this portion to gain better access to the aorta.
  • Step 3: Mobilization and Isolation - The fibromuscular bands (crura) of the diaphragm are separated, allowing for the mobilization of the aorta. After administering anticoagulants, vascular clamps are placed to isolate the aneurysm, ensuring that blood flow is controlled during the repair process.
  • Step 4: Aneurysm Sac Management - The aneurysm sac is opened, and any thrombus or plaque is removed. The walls of the artery are then repaired using sutures, and an autogenous (saphenous vein) or synthetic patch graft is applied as necessary to reinforce the artery.
  • Step 5: Alternative Techniques - Another technique involves excising the aneurysm and performing direct repair through end-to-end anastomosis of the distal and proximal vessel ends, with or without the insertion of a patch graft. Alternatively, a tube graft may be placed by making a longitudinal incision in the artery, inserting the graft, and suturing it to healthy artery segments both distal and proximal to the aneurysm.
  • Step 6: Closure and Recovery - After the graft is secured, the aneurysm sac is closed over the graft. The clamps are then released to restore blood flow. The retroperitoneum is repaired, and the abdominal incision is closed, completing the procedure.

3. Post-Procedure

Post-procedure care following the repair of an aneurysm or pseudoaneurysm includes monitoring the patient for any signs of complications, such as bleeding or infection. Patients may require pain management and will be observed for proper recovery of blood flow to the affected area. Follow-up imaging studies may be necessary to assess the integrity of the repair and ensure that there are no further complications. The healthcare team will provide specific instructions regarding activity restrictions and any necessary lifestyle modifications to promote healing and prevent recurrence.

Short Descr REPAIR DEFECT OF ARTERY
Medium Descr DIR RPR ANEURYSM HEPATIC/CELIAC/RENAL/MESENTERIC
Long Descr Direct repair of aneurysm, pseudoaneurysm, or excision (partial or total) and graft insertion, with or without patch graft; for aneurysm, pseudoaneurysm, and associated occlusive disease, hepatic, celiac, renal, or mesenteric artery
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 1 - 150% payment adjustment for bilateral procedures applies.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 2 - Payment restriction for assistants at surgery does not apply to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Inpatient Procedures, not paid under OPPS
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P2F - Major procedure, cardiovascular-Other
MUE 1
CCS Clinical Classification 61 - Other OR procedures on vessels other than head and neck

This is a primary code that can be used with these additional add-on codes.

35572 Addon Code MPFS Status: Active Code APC N ASC N1 CPT Assistant Article Illustration for Code Harvest of femoropopliteal vein, 1 segment, for vascular reconstruction procedure (eg, aortic, vena caval, coronary, peripheral artery) (List separately in addition to code for primary procedure)
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
50 Bilateral procedure: unless otherwise identified in the listings, bilateral procedures that are performed at the same session, should be identified by adding modifier 50 to the appropriate 5 digit code. note: this modifier should not be appended to designated "add-on" codes (see appendix d).
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
GC This service has been performed in part by a resident under the direction of a teaching physician
LT Left side (used to identify procedures performed on the left side of the body)
RT Right side (used to identify procedures performed on the right side of the body)
Date
Action
Notes
2013-01-01 Changed Medium Descriptor changed.
2002-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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