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Official Description

Exchange transfusion, blood; other than newborn

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 36455 refers to the procedure known as exchange transfusion, specifically for patients other than newborns. This medical intervention involves the systematic removal of a patient's blood and simultaneous replacement with donor blood, aimed at correcting various hematological conditions. The exchange transfusion is typically performed using a two-catheter push-pull technique, which is a method that allows for the efficient and controlled exchange of blood. In this technique, the physician carefully selects an appropriate artery and vein for the procedure. Blood is withdrawn from the designated artery while donor blood is infused through the vein at an equal rate, ensuring that the patient's blood volume is maintained throughout the process. This procedure is crucial in managing conditions such as severe anemia, hemolytic disease, or other blood disorders where rapid correction of blood composition is necessary. The exchange transfusion can significantly improve the patient's overall blood quality and restore normal physiological function.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The exchange transfusion procedure, coded as CPT® 36455, is indicated for various medical conditions that necessitate the rapid replacement of a patient's blood volume. The following are specific indications for performing this procedure:

  • Severe Anemia - This condition may arise from various causes, including chronic disease, nutritional deficiencies, or bone marrow disorders, necessitating the need for blood volume restoration.
  • Hemolytic Disease - Conditions such as hemolytic anemia or transfusion reactions can lead to the destruction of red blood cells, requiring exchange transfusion to remove damaged cells and replace them with healthy donor blood.
  • Blood Disorders - Certain hematological disorders may require exchange transfusion to correct abnormal blood composition and improve oxygen-carrying capacity.

2. Procedure

The exchange transfusion procedure involves several critical steps to ensure its effectiveness and safety. The following outlines the procedural steps involved in CPT® 36455:

  • Step 1: Preparation - The physician prepares the exchange equipment and ensures that all necessary materials, including donor blood, are ready for the procedure. This preparation is crucial for maintaining a sterile environment and ensuring the availability of blood products.
  • Step 2: Catheter Placement - Using a two-catheter push-pull technique, the physician selects an appropriate artery and vein for the procedure. Catheters are inserted into the selected sites, allowing for simultaneous blood withdrawal and infusion.
  • Step 3: Blood Exchange - Blood is withdrawn from the selected artery at a controlled rate. Concurrently, donor blood is infused through the vein at the same rate. This simultaneous process helps maintain hemodynamic stability and ensures that the patient's blood volume remains consistent throughout the exchange.
  • Step 4: Monitoring - Throughout the procedure, the physician closely monitors the patient's vital signs and overall condition to ensure safety and effectiveness. Adjustments may be made as necessary to optimize the exchange process.
  • Step 5: Completion - The procedure continues until the desired volume of blood has been exchanged, typically aiming to replace a significant portion of the patient's blood volume to achieve the therapeutic goals.

3. Post-Procedure

After the exchange transfusion is completed, the patient is monitored for any adverse reactions or complications that may arise from the procedure. This includes observing for signs of transfusion reactions, such as fever, chills, or changes in vital signs. The healthcare team may perform follow-up blood tests to assess the effectiveness of the transfusion and ensure that the patient's blood parameters have improved. Additionally, the patient may require supportive care and monitoring for a period to ensure a stable recovery and to address any potential issues that may arise post-procedure.

Short Descr BLD EXCHANGE TRUJ OTH THN NB
Medium Descr BLOOD EXCHANGE TRANSFUSION OTHER THAN NEWBORN
Long Descr Exchange transfusion, blood; other than newborn
Status Code Active Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Not Discounted when Multiple
ASC Payment Indicator Non office-based surgical procedure added in CY 2008 or later; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P1G - Major procedure - Other
MUE 1
CCS Clinical Classification 222 - Blood transfusion
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
GC This service has been performed in part by a resident under the direction of a teaching physician
Date
Action
Notes
2024-01-01 Changed Short and Medium Descriptions changed.
Pre-1990 Added Code added.
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