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Official Description

Biopsy of tongue; anterior two-thirds

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

Biopsy of the tongue, specifically the anterior two-thirds, is a medical procedure performed to assess abnormal growths, lesions, or areas of the tongue that appear suspicious. This incisional biopsy involves the careful removal of a small slice of tissue from the targeted area for further examination. Prior to the procedure, a local anesthetic is administered to ensure the patient experiences minimal discomfort during the biopsy. The surgeon then makes a precise incision in the tongue to extract the tissue sample. This sample is crucial for diagnostic purposes and is subsequently sent for pathology examination, which is reported separately. It is important to note that CPT® Code 41100 is designated for biopsies of the anterior two-thirds of the tongue, while CPT® Code 41105 is used for biopsies of the posterior two-thirds, highlighting the specificity required in coding for different anatomical regions of the tongue.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

Biopsy of the anterior two-thirds of the tongue is indicated for the following conditions:

  • Abnormal Growths The procedure is performed to evaluate any unusual or abnormal growths that may be present on the tongue.
  • Lesions It is indicated for the assessment of lesions that appear suspicious or atypical in nature.
  • Suspicious-Appearing Areas The biopsy is conducted to investigate areas of the tongue that exhibit signs of potential malignancy or other pathological changes.

2. Procedure

The procedure for performing a biopsy of the anterior two-thirds of the tongue involves several key steps:

  • Step 1: Anesthesia Administration The first step in the procedure is the administration of a local anesthetic at the site where the biopsy will be performed. This is crucial to ensure that the patient remains comfortable and experiences minimal pain during the procedure.
  • Step 2: Incision Following the administration of anesthesia, the surgeon makes a precise incision in the anterior two-thirds of the tongue. This incision is carefully placed to access the suspicious area while minimizing trauma to surrounding tissues.
  • Step 3: Tissue Removal After the incision is made, a slice of tissue is removed from the targeted area. This tissue sample is essential for further analysis and will be sent for pathology examination to determine the nature of the abnormality.
  • Step 4: Sample Handling The extracted tissue sample is handled according to standard protocols and is prepared for separate reporting in pathology. This ensures that the sample is properly preserved and documented for diagnostic evaluation.

3. Post-Procedure

After the biopsy procedure, the patient may experience some discomfort or swelling at the biopsy site, which is typically managed with over-the-counter pain relief medications. It is important for the patient to follow any post-procedure care instructions provided by the healthcare provider, which may include recommendations for oral hygiene and dietary modifications to avoid irritation of the biopsy site. The patient should also be informed about the expected recovery time and when to expect results from the pathology examination. Follow-up appointments may be necessary to discuss the findings and any further treatment options if required.

Short Descr BIOPSY OF TONGUE
Medium Descr BIOPSY TONGUE ANTERIOR TWO-THIRDS
Long Descr Biopsy of tongue; anterior two-thirds
Status Code Active Code
Global Days 010 - Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Multiple Reduction Applies
ASC Payment Indicator Office-based surgical procedure added to ASC list in CY 2008 or later with MPFS nonfacility PE RVUs; payment based on MPFS nonfacility PE RVUs.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P5E - Ambulatory procedures - other
MUE 2
CCS Clinical Classification 31 - Diagnostic procedures on nose, mouth and pharynx
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
GA Waiver of liability statement issued as required by payer policy, individual case
GC This service has been performed in part by a resident under the direction of a teaching physician
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
25 Significant, separately identifiable evaluation and management service by the same physician or other qualified health care professional on the same day of the procedure or other service: it may be necessary to indicate that on the day a procedure or service identified by a cpt code was performed, the patient's condition required a significant, separately identifiable e/m service above and beyond the other service provided or beyond the usual preoperative and postoperative care associated with the procedure that was performed. a significant, separately identifiable e/m service is defined or substantiated by documentation that satisfies the relevant criteria for the respective e/m service to be reported (see evaluation and management services guidelines for instructions on determining level of e/m service). the e/m service may be prompted by the symptom or condition for which the procedure and/or service was provided. as such, different diagnoses are not required for reporting of the e/m services on the same date. this circumstance may be reported by adding modifier 25 to the appropriate level of e/m service. note: this modifier is not used to report an e/m service that resulted in a decision to perform surgery. see modifier 57 for significant, separately identifiable non-e/m services, see modifier 59.
50 Bilateral procedure: unless otherwise identified in the listings, bilateral procedures that are performed at the same session, should be identified by adding modifier 50 to the appropriate 5 digit code. note: this modifier should not be appended to designated "add-on" codes (see appendix d).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
AG Primary physician
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
CR Catastrophe/disaster related
FS Split (or shared) evaluation and management visit
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
LT Left side (used to identify procedures performed on the left side of the body)
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
RT Right side (used to identify procedures performed on the right side of the body)
SG Ambulatory surgical center (asc) facility service
X3 Episodic/broad services: for reporting services by clinicians who have broad responsibility for the comprehensive needs of the patient that is limited to a defined period and circumstance such as a hospitalization; reporting clinician service examples include but are not limited to the hospitalist's services rendered providing comprehensive and general care to a patient while admitted to the hospital
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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