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Official Description

Vagotomy including pyloroplasty, with or without gastrostomy; parietal cell (highly selective)

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 43641 involves a highly selective vagotomy, which is a surgical intervention targeting the vagus nerve, specifically its branches that innervate the stomach. The vagus nerve, known as the tenth cranial nerve, plays a crucial role in regulating various bodily functions, including the production of gastric acid. By cutting the vagus nerve, the procedure aims to reduce excessive acid secretion, thereby helping to prevent the formation of peptic ulcers. This surgical approach is particularly beneficial for patients suffering from conditions related to hypersecretion of gastric acid. The operation typically requires a midline upper abdominal incision to access the stomach and the vagus nerve. During the procedure, the surgeon identifies and dissects the vagus nerve, following it to the parietal cell branches, which are responsible for stimulating acid production in the stomach. The division of these branches is essential for achieving the desired therapeutic effect. Additionally, to address potential complications related to gastric motility and delayed gastric emptying that may arise from vagotomy, a pyloroplasty is performed. This involves enlarging the opening from the stomach to the duodenum, facilitating better gastric drainage. In some cases, a gastrostomy may also be performed, allowing for direct access to the stomach for feeding or other medical interventions. Overall, CPT® Code 43641 encompasses a complex surgical procedure aimed at managing gastric acid-related disorders through precise nerve manipulation and supportive surgical techniques.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure described by CPT® Code 43641 is indicated for patients experiencing conditions related to excessive gastric acid production. The following are specific indications for performing a highly selective vagotomy:

  • Peptic Ulcers: Patients with recurrent peptic ulcers that are resistant to medical management may benefit from this procedure to reduce acid secretion.
  • Gastric Hypersecretion: Conditions characterized by excessive gastric acid production, leading to complications such as gastritis or esophagitis, may warrant this surgical intervention.
  • Gastric Outlet Obstruction: In cases where gastric outlet obstruction is caused by peptic ulcers, vagotomy combined with pyloroplasty can help alleviate symptoms.

2. Procedure

The procedure for CPT® Code 43641 involves several critical steps to ensure effective surgical intervention:

  • Step 1: Incision and Exposure A midline upper abdominal incision is made to provide access to the stomach and the vagus nerve. This incision allows the surgeon to visualize and manipulate the necessary anatomical structures.
  • Step 2: Identification of the Vagus Nerve The vagus nerve is carefully identified and freed from surrounding tissues. This step is crucial for ensuring that the nerve can be accurately dissected without damaging adjacent structures.
  • Step 3: Highly Selective Vagotomy The surgeon follows the vagus nerve to the Latarjet's nerve branches, also known as the parietal cell branches. These branches are then divided starting at the esophagogastric junction and continuing along the lesser curvature of the stomach, effectively reducing acid production.
  • Step 4: Pyloroplasty To address potential gastric motility issues, a pyloroplasty is performed. The pyloric sphincter is incised longitudinally, and the incision is repaired transversely to enlarge the opening from the stomach to the duodenum, facilitating gastric drainage.
  • Step 5: Gastrostomy (if indicated) If a gastrostomy is required, two concentric purse-string sutures are placed around the planned incision site on the stomach. The serosa is incised, and a small portion of the inner mucosal layer is excised to create an opening. A balloon catheter is then inserted, inflated, and secured in place with the purse-string sutures.
  • Step 6: Catheter Exteriorization The stomach is positioned against the abdominal wall, and a stab incision is made in the abdomen to exteriorize the catheter. The catheter is grasped and brought out through the abdominal wall, allowing for access to the stomach.
  • Step 7: Closure Finally, anchoring sutures are placed on the internal abdominal wall, and the abdominal incision is closed in layers to ensure proper healing and minimize complications.

3. Post-Procedure

After the completion of the procedure, patients typically require monitoring for any complications related to the surgery. Post-operative care may include managing pain, monitoring for signs of infection, and ensuring proper gastric drainage. Patients may experience changes in gastric motility, and dietary modifications may be necessary during the recovery period. Follow-up appointments are essential to assess healing and the effectiveness of the procedure in reducing gastric acid production and preventing peptic ulcers.

Short Descr VAGOTOMY & PYLORUS REPAIR
Medium Descr VGTMY W/PYLOROPLASTY W/WO GASTROST PARIETAL CELL
Long Descr Vagotomy including pyloroplasty, with or without gastrostomy; parietal cell (highly selective)
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 2 - Payment restriction for assistants at surgery does not apply to this procedure...
Co-Surgeons (62) 1 - Co-surgeons could be paid, though supporting documentation is required...
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Inpatient Procedures, not paid under OPPS
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P1G - Major procedure - Other
MUE 1
CCS Clinical Classification 94 - Other OR upper GI therapeutic procedures
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
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2013-01-01 Changed Guideline information changed.
Pre-1990 Added Code added.
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