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Official Description

Small intestinal endoscopy, enteroscopy beyond second portion of duodenum, not including ileum; with biopsy, single or multiple

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 44361 refers to a specific medical procedure known as small intestinal endoscopy, specifically an enteroscopy that extends beyond the second portion of the duodenum, excluding the ileum. This procedure involves the use of a flexible fiberoptic endoscope, which is a specialized instrument designed for visual examination and intervention within the gastrointestinal tract. During the endoscopy, the physician can inspect the mucosal surfaces of the small intestine, particularly the jejunum, for any abnormalities or pathological conditions. The procedure may also involve the collection of tissue samples through biopsies, which can be single or multiple, allowing for further laboratory analysis of the collected specimens. The endoscopic examination is initiated by numbing the patient's mouth and throat with an anesthetic spray, followed by the insertion of a hollow mouthpiece to facilitate the swallowing of the endoscope. The endoscope is carefully advanced through the digestive tract, providing direct visualization of the intestinal lining and enabling the physician to identify any irregularities. This procedure is crucial for diagnosing various gastrointestinal disorders and conditions that may affect the small intestine.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure described by CPT® Code 44361 is indicated for various gastrointestinal conditions that necessitate direct visualization and potential biopsy of the small intestine beyond the second portion of the duodenum. The following are specific indications for performing this procedure:

  • Suspected Small Intestinal Disorders - This includes conditions such as Crohn's disease, small intestinal tumors, or other inflammatory processes that may affect the jejunum.
  • Unexplained Gastrointestinal Symptoms - Patients presenting with symptoms such as chronic diarrhea, abdominal pain, or gastrointestinal bleeding may require this procedure for diagnostic purposes.
  • Evaluation of Malabsorption Syndromes - Conditions that lead to malabsorption of nutrients may necessitate examination of the small intestine to identify underlying causes.
  • Follow-Up of Previous Findings - Patients with prior endoscopic findings that require further investigation or biopsy may be indicated for this procedure.

2. Procedure

The procedure for CPT® Code 44361 involves several critical steps to ensure a thorough examination of the small intestine. The following outlines the procedural steps:

  • Preparation of the Patient - Prior to the procedure, the patient is prepared by administering an anesthetic spray to numb the mouth and throat, which helps minimize discomfort during the endoscopy. A hollow mouthpiece is then placed in the patient's mouth to facilitate the swallowing of the endoscope.
  • Insertion of the Endoscope - The flexible fiberoptic endoscope is carefully inserted into the patient's mouth and advanced as the patient swallows. The endoscope is guided through the esophagus and into the stomach, and then into the duodenum, specifically beyond the second portion.
  • Inspection of the Mucosal Surfaces - Once the endoscope is positioned beyond the second portion of the duodenum, the physician inspects the mucosal surfaces of the small intestine, including the jejunum, for any abnormalities such as lesions, inflammation, or other pathological changes.
  • Biopsy Procedure - If any suspicious areas are identified, the physician will proceed to obtain tissue samples. Biopsy forceps are introduced through the biopsy channel of the endoscope, and the targeted tissue is grasped and removed. This may involve multiple biopsies depending on the findings.
  • Withdrawal of the Endoscope - After the examination and any necessary biopsies are completed, the endoscope is carefully withdrawn. The physician may conduct a final inspection of the duodenum and jejunum during withdrawal to ensure a comprehensive evaluation.

3. Post-Procedure

After the completion of the procedure, patients are typically monitored for a short period to ensure there are no immediate complications. It is common for patients to experience some throat discomfort or mild abdominal cramping following the endoscopy. The physician will provide specific post-procedure care instructions, which may include dietary recommendations and activity restrictions. Additionally, any tissue samples obtained during the procedure will be sent for laboratory analysis, and the results will be discussed with the patient in a follow-up appointment. Patients should be advised to report any unusual symptoms, such as severe abdominal pain, fever, or persistent bleeding, to their healthcare provider promptly.

Short Descr SMALL BOWEL ENDOSCOPY/BIOPSY
Medium Descr ENDOSCOPY UPPER SMALL INTESTINE W/BIOPSY
Long Descr Small intestinal endoscopy, enteroscopy beyond second portion of duodenum, not including ileum; with biopsy, single or multiple
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 3 - Special payment adjustment rules for multiple endoscopic procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Endoscopic Base Code 44360  Small intestinal endoscopy, enteroscopy beyond second portion of duodenum, not including ileum; diagnostic, including collection of specimen(s) by brushing or washing, when performed (separate procedure)
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P8I - Endoscopy - other
MUE 1
CCS Clinical Classification 70 - Upper gastrointestinal endoscopy, biopsy
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
SG Ambulatory surgical center (asc) facility service
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
GC This service has been performed in part by a resident under the direction of a teaching physician
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
74 Discontinued out-patient hospital/ambulatory surgery center (asc) procedure after administration of anesthesia: due to extenuating circumstances or those that threaten the well being of the patient, the physician may terminate a surgical or diagnostic procedure after the administration of anesthesia (local, regional block(s), general) or after the procedure was started (incision made, intubation started, scope inserted, etc). under these circumstances, the procedure started but terminated can be reported by its usual procedure number and the addition of modifier 74. note: the elective cancellation of a service prior to the administration of anesthesia and/or surgical preparation of the patient should not be reported. for physician reporting of a discontinued procedure, see modifier 53.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
AG Primary physician
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
CR Catastrophe/disaster related
GA Waiver of liability statement issued as required by payer policy, individual case
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
PT Colorectal cancer screening test; converted to diagnostic test or other procedure
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
QJ Services/items provided to a prisoner or patient in state or local custody, however the state or local government, as applicable, meets the requirements in 42 cfr 411.4 (b)
QS Monitored anesthesia care service
QY Medical direction of one certified registered nurse anesthetist (crna) by an anesthesiologist
X2 Continuous/focused services: for reporting services by clinicians whose expertise is needed for the ongoing management of a chronic disease or a condition that needs to be managed and followed with no planned endpoint to the relationship; reporting clinician service examples include but are not limited to: a rheumatologist taking care of the patient's rheumatoid arthritis longitudinally but not providing general primary care services
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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2017-01-01 Changed Moderate (Conscious) Sedation flag removed. See new Moderate Sedation category.
Pre-1990 Added Code added.
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