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Official Description

Anoscopy; with biopsy, single or multiple

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

Anoscopy is a medical procedure that involves the visual inspection of the anus and lower rectum using a specialized instrument called an anoscope. This procedure is often performed to evaluate various conditions affecting the anal region. During anoscopy, a digital rectal exam may also be conducted to assess the area further. The anoscope is equipped with an obturator, which facilitates its insertion into the anus. The physician advances the anoscope using a gentle twisting motion while the patient bears down, allowing for easier passage. Once the anoscope is in place, the obturator is removed, and an eyepiece is attached to enable visualization of the anal canal and rectal mucosa. The physician carefully inspects the mucosal surface for any abnormalities. If necessary, biopsy forceps can be introduced through the biopsy channel of the endoscope to obtain tissue samples. These samples are crucial for diagnosing various conditions, as they are sent for laboratory analysis to determine the presence of any pathological changes. The procedure can involve obtaining one or multiple biopsies, depending on the findings during the inspection.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

Indications for performing an anoscopy with biopsy include the following:

  • Rectal bleeding The presence of blood in the stool or from the rectum may necessitate an anoscopy to identify the source of the bleeding.
  • Anal pain Patients experiencing pain in the anal region may require this procedure to evaluate potential causes such as fissures, hemorrhoids, or other abnormalities.
  • Suspicion of anal lesions Any suspected lesions, such as polyps or tumors, warrant an anoscopy to allow for direct visualization and biopsy if necessary.
  • Monitoring of known conditions Patients with a history of anal or rectal conditions may undergo this procedure for surveillance and to assess any changes in their condition.

2. Procedure

The procedure for anoscopy with biopsy involves several key steps that ensure a thorough examination and safe tissue sampling:

  • Step 1: Preparation The patient is positioned comfortably, typically in a lateral or supine position, to facilitate access to the anal area. The physician explains the procedure to the patient and obtains informed consent.
  • Step 2: Insertion of the anoscope The anoscope, equipped with an obturator, is gently inserted into the anus. The physician uses a twisting motion while the patient bears down to ease the insertion process.
  • Step 3: Visualization Once the anoscope is in place, the obturator is removed, and an eyepiece is attached. The physician then inspects the anal canal and rectal mucosa for any abnormalities, such as lesions or inflammation.
  • Step 4: Biopsy procedure If any suspicious areas are identified, biopsy forceps are introduced through the biopsy channel of the anoscope. The forceps are opened to capture a tissue sample from the targeted area.
  • Step 5: Sample retrieval After obtaining the tissue sample, the forceps are closed and carefully removed from the anoscope, ensuring that the biopsy is intact. The sample is then prepared for laboratory analysis.
  • Step 6: Completion The anoscope is withdrawn, and the procedure is concluded. The physician may provide post-procedure instructions to the patient regarding care and follow-up.

3. Post-Procedure

After the anoscopy with biopsy, patients may experience some discomfort or minor bleeding, which is typically expected. It is important for patients to follow any post-procedure care instructions provided by the physician. They may be advised to avoid strenuous activities and to monitor for any signs of excessive bleeding or infection. Follow-up appointments may be scheduled to discuss biopsy results and any further management based on the findings.

Short Descr ANOSCOPY AND BIOPSY
Medium Descr ANOSCOPY W/BX SINGLE/MULTIPLE
Long Descr Anoscopy; with biopsy, single or multiple
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 3 - Special payment adjustment rules for multiple endoscopic procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Endoscopic Base Code 46600  Anoscopy; diagnostic, including collection of specimen(s) by brushing or washing, when performed (separate procedure)
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Multiple Reduction Applies
ASC Payment Indicator Office-based surgical procedure added to ASC list in CY 2008 or later with MPFS nonfacility PE RVUs; payment based on MPFS nonfacility PE RVUs.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P8I - Endoscopy - other
MUE 1
CCS Clinical Classification 77 - Proctoscopy and anorectal biopsy
GC This service has been performed in part by a resident under the direction of a teaching physician
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
AG Primary physician
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
CR Catastrophe/disaster related
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
SG Ambulatory surgical center (asc) facility service
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
2011-01-01 Changed Guideline information changed.
Pre-1990 Added Code added.
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