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Official Description

Biopsy of liver, wedge

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 47100 refers to a wedge biopsy of the liver, which is a surgical technique used to obtain a small, triangular section of liver tissue for diagnostic examination. This procedure is typically performed to investigate liver diseases or conditions that may not be identifiable through non-invasive imaging techniques. The biopsy allows for histological analysis, which can provide critical information regarding the presence of liver pathology, such as cirrhosis, hepatitis, or tumors. The surgical approach involves making an incision in the right subcostal region, which is the area beneath the rib cage on the right side of the body where the liver is located. During the procedure, the right rectus muscle is transected, and the oblique muscles are split to gain access to the liver. The sternum is retracted to facilitate visibility and access to the biopsy site. Once the appropriate area of the liver is identified, a wedge-shaped section is excised. After the tissue is removed, measures are taken to control any bleeding, the wound is irrigated to prevent infection, and the incision site is subsequently closed. This procedure is essential for obtaining tissue samples that can lead to accurate diagnoses and appropriate treatment plans for patients with liver-related health issues.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

Wedge biopsy of the liver, as described by CPT® Code 47100, is indicated for several clinical scenarios where liver tissue examination is necessary for diagnosis. The following conditions may warrant this procedure:

  • Suspected Liver Disease - When there is a suspicion of liver disease, such as hepatitis or cirrhosis, that requires histological confirmation.
  • Evaluation of Liver Masses - To assess the nature of liver masses or lesions that may be indicative of tumors, whether benign or malignant.
  • Unexplained Liver Dysfunction - In cases of unexplained liver dysfunction or abnormal liver function tests, a biopsy may be necessary to determine the underlying cause.

2. Procedure

The wedge biopsy of the liver involves several critical procedural steps to ensure successful tissue acquisition. The following outlines the detailed steps involved in the procedure:

  • Step 1: Anesthesia and Positioning - The patient is positioned appropriately, typically in a supine position, and anesthesia is administered to ensure comfort and pain management during the procedure.
  • Step 2: Incision - A small incision is made in the right subcostal region, which allows access to the liver. This incision is strategically placed to minimize trauma to surrounding tissues.
  • Step 3: Muscle Transection and Splitting - The right rectus muscle is transected, and the oblique muscles are split to provide adequate exposure to the liver. This step is crucial for accessing the liver without causing excessive damage to the abdominal wall.
  • Step 4: Retraction of the Sternum - The sternum is retracted to enhance visibility and access to the liver, allowing the surgeon to identify the precise biopsy site.
  • Step 5: Identification and Excision of Biopsy Site - The specific area of the liver to be biopsied is identified, and a wedge-shaped section of liver tissue is excised. This wedge shape is important for obtaining a representative sample of liver tissue.
  • Step 6: Hemostasis and Wound Management - After the tissue is removed, any bleeding is controlled through appropriate hemostatic techniques. The biopsy site is then irrigated to reduce the risk of infection.
  • Step 7: Closure of Incision - Finally, the incision site is closed using sutures or staples, ensuring that the wound is properly secured for healing.

3. Post-Procedure

After the wedge biopsy of the liver, patients are typically monitored for any immediate complications, such as bleeding or infection. Post-procedure care may include pain management and instructions for activity restrictions to promote healing. Patients may be advised to avoid strenuous activities for a specified period. Follow-up appointments are essential to discuss biopsy results and any further management based on the findings. It is also important for patients to report any unusual symptoms, such as excessive pain or signs of infection, to their healthcare provider promptly.

Short Descr WEDGE BIOPSY OF LIVER
Medium Descr BIOPSY LIVER WEDGE
Long Descr Biopsy of liver, wedge
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 2 - Payment restriction for assistants at surgery does not apply to this procedure...
Co-Surgeons (62) 1 - Co-surgeons could be paid, though supporting documentation is required...
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Inpatient Procedures, not paid under OPPS
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P1G - Major procedure - Other
MUE 3
CCS Clinical Classification 83 - Biopsy of liver

This is a primary code that can be used with these additional add-on codes.

96547 Add On Code MPFS Status: Active Code APC N Intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) procedure, including separate incision(s) and closure, when performed; first 60 minutes (List separately in addition to code for primary procedure)
96548 Add On Code MPFS Status: Active Code APC N Intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) procedure, including separate incision(s) and closure, when performed; each additional 30 minutes (List separately in addition to code for primary procedure)
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
GC This service has been performed in part by a resident under the direction of a teaching physician
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
CR Catastrophe/disaster related
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
54 Surgical care only: when 1 physician or other qualified health care professional performs a surgical procedure and another provides preoperative and/or postoperative management, surgical services may be identified by adding modifier 54 to the usual procedure number.
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
62 Two surgeons: when 2 surgeons work together as primary surgeons performing distinct part(s) of a procedure, each surgeon should report his/her distinct operative work by adding modifier 62 to the procedure code and any associated add-on code(s) for that procedure as long as both surgeons continue to work together as primary surgeons. each surgeon should report the co-surgery once using the same procedure code. if additional procedure(s) (including add-on procedure(s) are performed during the same surgical session, separate code(s) may also be reported with modifier 62 added. note: if a co-surgeon acts as an assistant in the performance of additional procedure(s), other than those reported with the modifier 62, during the same surgical session, those services may be reported using separate procedure code(s) with modifier 80 or modifier 82 added, as appropriate.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
LT Left side (used to identify procedures performed on the left side of the body)
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
RT Right side (used to identify procedures performed on the right side of the body)
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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