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Official Description

Liver allotransplantation, orthotopic, partial or whole, from cadaver or living donor, any age

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

Liver allotransplantation, as described by CPT® Code 47135, refers to the surgical procedure in which a liver is transplanted from a donor—either a cadaver or a living individual—into a recipient. This procedure can involve the transplantation of either a partial or whole liver and is performed in an orthotopic manner, meaning the donor liver is placed in the same anatomical position as the original liver. The surgery typically begins with a bilateral subcostal incision, which may be extended with an upper midline incision to provide adequate access to the liver. During the operation, various anatomical structures are carefully dissected and ligated, including the hepatic artery and bile duct, to facilitate the removal of the diseased liver. The procedure also involves the use of venovenous bypass to manage blood flow during the transplantation process. Once the diseased liver is excised, the donor liver graft is positioned and connected to the recipient's blood vessels and bile duct, ensuring proper anastomosis for functionality. This complex surgical intervention is critical for patients with end-stage liver disease or acute liver failure, providing them with a chance for improved health and quality of life.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The indications for liver allotransplantation (CPT® Code 47135) include a variety of conditions that lead to severe liver dysfunction or failure. These conditions necessitate the need for a liver transplant to restore normal liver function and improve the patient's quality of life. The following are explicitly provided indications for this procedure:

  • End-stage liver disease - This includes chronic liver diseases such as cirrhosis, which may result from various etiologies including viral hepatitis, alcoholic liver disease, or non-alcoholic fatty liver disease.
  • Acute liver failure - A rapid deterioration of liver function that can occur due to factors such as drug toxicity, viral infections, or autoimmune diseases.
  • Metabolic liver diseases - Conditions such as Wilson's disease or hemochromatosis that lead to the accumulation of toxic substances in the liver.
  • Liver tumors - Certain primary liver cancers or metastatic liver disease that cannot be managed by other means.

2. Procedure

The procedure for liver allotransplantation involves several critical steps to ensure the successful transplantation of the liver. Each step is meticulously performed to minimize complications and optimize outcomes:

  • Step 1: Incision and Exposure - The surgical team begins by making a bilateral subcostal incision, which may be extended with an upper midline incision to provide adequate access to the liver. This approach allows for optimal visualization and manipulation of the liver and surrounding structures.
  • Step 2: Dissection of Anatomical Structures - The falciform ligament is taken down to facilitate access to the liver. The porta hepatis, which contains the hepatic artery, portal vein, and bile duct, is carefully dissected to prepare for the subsequent steps of the procedure.
  • Step 3: Vascular Control - The hepatic artery is ligated to prevent blood flow to the diseased liver. The bile duct is transected as close to the liver as possible to allow for proper anastomosis later. The portal vein is isolated, and venovenous bypass is initiated to manage blood circulation during the removal of the liver.
  • Step 4: Removal of the Diseased Liver - The hepatic triangular ligaments are taken down, and the inferior vena cava is located. The vena cava is cross-clamped above and below the liver, allowing for the complete removal of the diseased liver.
  • Step 5: Placement of the Donor Graft - The donor liver graft is placed in the usual anatomic position (orthotopic placement) and is flushed to remove any preservation solution that may have been used prior to transplantation.
  • Step 6: Anastomosis of Blood Vessels - The anastomosis begins with the portal vein, followed by the arterial anastomosis, ensuring that the blood supply to the new liver is established.
  • Step 7: Bile Duct Anastomosis - The bile duct from the donor liver is anastomosed to the recipient's bile duct. Alternatively, the donor bile duct may be implanted into the recipient's jejunum if necessary.
  • Step 8: Drain Placement and Closure - A T-tube is placed in the bile duct for external drainage, and additional drains may be placed in the abdomen as needed. Finally, the abdominal incision is closed, completing the procedure.

3. Post-Procedure

After the liver allotransplantation procedure, patients typically require close monitoring in a postoperative setting to assess for any complications such as bleeding, infection, or rejection of the transplanted liver. The expected recovery period may vary depending on the individual patient's condition and the complexity of the surgery. Patients will often be placed on immunosuppressive medications to prevent rejection of the donor liver. Follow-up care is crucial, including regular laboratory tests to monitor liver function and ensure the health of the transplanted organ. Additional considerations may include dietary modifications and lifestyle changes to support recovery and overall health.

Short Descr TRANSPLANTATION OF LIVER
Medium Descr LVR ALTRNSPLJ ORTHOTOPIC PRTL/WHL DON ANY AGE
Long Descr Liver allotransplantation, orthotopic, partial or whole, from cadaver or living donor, any age
Status Code Restricted Coverage
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 2 - Payment restriction for assistants at surgery does not apply to this procedure...
Co-Surgeons (62) 1 - Co-surgeons could be paid, though supporting documentation is required...
Team Surgery (66) 2 - Team surgeons permitted; pay by report.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Inpatient Procedures, not paid under OPPS
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P1G - Major procedure - Other
MUE 1
CCS Clinical Classification 176 - Other organ transplantation
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
62 Two surgeons: when 2 surgeons work together as primary surgeons performing distinct part(s) of a procedure, each surgeon should report his/her distinct operative work by adding modifier 62 to the procedure code and any associated add-on code(s) for that procedure as long as both surgeons continue to work together as primary surgeons. each surgeon should report the co-surgery once using the same procedure code. if additional procedure(s) (including add-on procedure(s) are performed during the same surgical session, separate code(s) may also be reported with modifier 62 added. note: if a co-surgeon acts as an assistant in the performance of additional procedure(s), other than those reported with the modifier 62, during the same surgical session, those services may be reported using separate procedure code(s) with modifier 80 or modifier 82 added, as appropriate.
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
GC This service has been performed in part by a resident under the direction of a teaching physician
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
66 Surgical team: under some circumstances, highly complex procedures (requiring the concomitant services of several physicians or other qualified health care professionals, often of different specialties, plus other highly skilled, specially trained personnel, various types of complex equipment) are carried out under the "surgical team" concept. such circumstances may be identified by each participating individual with the addition of modifier 66 to the basic procedure number used for reporting services.
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
81 Minimum assistant surgeon: minimum surgical assistant services are identified by adding modifier 81 to the usual procedure number.
CR Catastrophe/disaster related
GW Service not related to the hospice patient's terminal condition
GZ Item or service expected to be denied as not reasonable and necessary
Q0 Investigational clinical service provided in a clinical research study that is in an approved clinical research study
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
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2016-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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