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Official Description

Excision of ampulla of Vater

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 48148 involves the excision of the ampulla of Vater, a critical anatomical structure located at the junction of the bile duct and the pancreatic duct within the second part of the duodenum. This surgical intervention, commonly referred to as an ampullectomy, is performed to address various conditions affecting the ampulla, such as tumors or obstructions. The procedure typically requires a subcostal or midline incision in the abdomen to provide access to the duodenum. Once the incision is made, the surgeon mobilizes the second part of the duodenum to facilitate the excision. The use of stay sutures in the duodenal wall helps stabilize the area during the operation. A catheter is then utilized to cannulate the bile and pancreatic ducts, allowing for precise manipulation and resection. The duodenal mucosa surrounding the ampulla of Vater is carefully resected, followed by the transection of the biliary and pancreatic ducts. The excision of the ampulla is performed with attention to the surrounding structures to minimize complications. After the ampulla is removed, the biliary and pancreatic ducts are reconstructed by approximating their common walls and suturing them to the duodenal wall. This reconstruction is critical for restoring normal drainage into the duodenum, and the ducts are probed with biliary dilators to ensure they are of adequate size. Finally, the duodenum is closed, and the surgical wound is irrigated with normal saline. In some cases, drains may be placed to facilitate postoperative drainage, and the abdomen is subsequently closed around these drains to complete the procedure.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The excision of the ampulla of Vater, as described by CPT® Code 48148, is indicated for various clinical conditions that may affect the ampulla and surrounding structures. These indications include:

  • Malignancy - Presence of tumors at the ampulla of Vater that may require surgical removal to prevent further complications or metastasis.
  • Obstruction - Blockages in the bile or pancreatic ducts that can lead to significant gastrointestinal issues, necessitating the excision of the ampulla to restore normal function.
  • Chronic Inflammation - Conditions such as chronic pancreatitis or cholangitis that may cause persistent inflammation and require surgical intervention.

2. Procedure

The procedure for excising the ampulla of Vater involves several critical steps, each designed to ensure the safe and effective removal of the ampulla while preserving surrounding structures. The steps include:

  • Incision - A subcostal or midline incision is made in the abdomen to provide access to the duodenum and the ampulla of Vater.
  • Mobilization of the Duodenum - The second part of the duodenum is carefully mobilized to allow for adequate exposure of the ampulla and surrounding tissues.
  • Placement of Stay Sutures - Stay sutures are placed in the duodenal wall to stabilize the area during the procedure, facilitating better access and visibility.
  • Cannulation of Ducts - A catheter is used to cannulate the bile and pancreatic ducts, which is essential for the subsequent steps of the procedure.
  • Resection of Duodenal Mucosa - The duodenal mucosa surrounding the ampulla of Vater is resected to expose the ampulla for excision.
  • Transection of Ducts - The biliary and pancreatic ducts are transected, allowing for the removal of the ampulla of Vater.
  • Excision of the Ampulla - The ampulla of Vater is excised, taking care to minimize damage to adjacent structures.
  • Reconstruction of Ducts - The biliary and pancreatic ducts are reconstructed by approximating their common walls and suturing them to the duodenal wall to restore normal drainage.
  • Probing of Ducts - Biliary dilators are used to probe the ducts, ensuring they are of adequate size for proper function.
  • Closure of the Duodenum - The duodenum is closed after verifying that drainage from the ducts into the duodenum is adequate.
  • Wound Irrigation and Drain Placement - The surgical wound is flushed with normal saline, and drains may be placed as necessary to facilitate postoperative drainage.
  • Closure of the Abdomen - The abdomen is closed around the drains, completing the surgical procedure.

3. Post-Procedure

After the excision of the ampulla of Vater, patients typically require careful monitoring and management to ensure proper recovery. Post-procedure care may include pain management, monitoring for signs of infection, and ensuring that the drainage from the surgical site is adequate. Patients may also need to follow specific dietary guidelines as they recover, particularly if there are changes in digestive function due to the surgery. Follow-up appointments are essential to assess healing and the functionality of the reconstructed ducts, ensuring that there are no complications such as strictures or leaks. Overall, the recovery process will vary based on individual patient factors and the complexity of the procedure.

Short Descr REMOVAL OF PANCREATIC DUCT
Medium Descr EXCISION AMPULLA VATER
Long Descr Excision of ampulla of Vater
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 2 - Payment restriction for assistants at surgery does not apply to this procedure...
Co-Surgeons (62) 1 - Co-surgeons could be paid, though supporting documentation is required...
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Inpatient Procedures, not paid under OPPS
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P1G - Major procedure - Other
MUE 1
CCS Clinical Classification 99 - Other OR gastrointestinal therapeutic procedures
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
62 Two surgeons: when 2 surgeons work together as primary surgeons performing distinct part(s) of a procedure, each surgeon should report his/her distinct operative work by adding modifier 62 to the procedure code and any associated add-on code(s) for that procedure as long as both surgeons continue to work together as primary surgeons. each surgeon should report the co-surgery once using the same procedure code. if additional procedure(s) (including add-on procedure(s) are performed during the same surgical session, separate code(s) may also be reported with modifier 62 added. note: if a co-surgeon acts as an assistant in the performance of additional procedure(s), other than those reported with the modifier 62, during the same surgical session, those services may be reported using separate procedure code(s) with modifier 80 or modifier 82 added, as appropriate.
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
GC This service has been performed in part by a resident under the direction of a teaching physician
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