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Official Description

Backbench standard preparation of cadaver donor pancreas allograft prior to transplantation, including dissection of allograft from surrounding soft tissues, splenectomy, duodenotomy, ligation of bile duct, ligation of mesenteric vessels, and Y-graft arterial anastomoses from iliac artery to superior mesenteric artery and to splenic artery

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 48551 refers to the backbench standard preparation of a cadaver donor pancreas allograft prior to transplantation. This procedure is critical in ensuring that the pancreas is adequately prepared for successful transplantation into a recipient. The process begins with the careful removal of the pancreas from its sterile container, where it is then placed on ice and immersed in a cold preservation solution to maintain its viability. A thorough inspection of the pancreas is conducted to confirm that it is intact and suitable for transplant. This preparation involves several intricate steps, including the removal of the attached spleen through the careful ligation and division of splenic vessels, as well as the opening of the duodenum to locate the sphincter of Oddi. A catheter is utilized to navigate through the common bile duct, confirming the correct positioning of the sphincter. The duodenum is then shortened at both ends, and the mesenteric vessels are ligated and divided to facilitate the separation of the duodenum from the distal pancreas. The remaining duodenum is secured by stapling and oversewing its ends. Additionally, the common bile duct is ligated, and the middle colic vessels are ligated at the base of the transverse mesocolon, along with the superior mesenteric vessels at the root of the small bowel mesentery. A Y-graft is constructed to connect the external and internal iliac arteries to the superior mesenteric artery, ensuring proper vascular supply to the pancreas. Throughout this meticulous preparation, the pancreas remains on ice and continues to be bathed in cold preservation solution until the recipient is ready for transplantation.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The backbench standard preparation of a cadaver donor pancreas allograft is indicated for the following conditions:

  • Pancreatic Insufficiency - Conditions where the pancreas fails to produce sufficient enzymes for digestion.
  • Type 1 Diabetes Mellitus - A condition characterized by the autoimmune destruction of insulin-producing beta cells in the pancreas.
  • Pancreatic Cancer - Malignancies that necessitate the removal of the pancreas and subsequent transplantation of a healthy allograft.
  • Severe Pancreatitis - Chronic inflammation of the pancreas that may lead to irreversible damage and the need for transplantation.

2. Procedure

The procedure for backbench preparation of the cadaver donor pancreas allograft involves several critical steps:

  • Step 1: Removal from Sterile Container - The pancreas is carefully extracted from its sterile container to prevent contamination, ensuring that it remains in optimal condition for transplantation.
  • Step 2: Cooling and Preservation - Once removed, the pancreas is placed on ice and immersed in a cold preservation solution, which is essential for maintaining the organ's viability during the preparation process.
  • Step 3: Inspection - A thorough inspection of the pancreas is conducted to verify that it is intact and healthy enough for transplantation, assessing its overall condition and suitability.
  • Step 4: Splenectomy - The attached spleen is removed by carefully ligating and dividing the splenic vessels, ensuring that the pancreas is free from surrounding tissues.
  • Step 5: Duodenotomy - The duodenum is opened to locate the sphincter of Oddi, which is crucial for the subsequent steps of the procedure.
  • Step 6: Catheter Insertion - A catheter is inserted into the common bile duct and passed through the sphincter of Oddi to confirm its location, facilitating further dissection.
  • Step 7: Shortening the Duodenum - The duodenum is shortened both proximally and distally to prepare it for anastomosis during transplantation.
  • Step 8: Ligation of Mesenteric Vessels - The mesenteric vessels are ligated and divided as the duodenum is separated from the distal pancreas, ensuring proper vascular control.
  • Step 9: Stapling and Oversewing - Both ends of the remaining duodenum are stapled and oversewn to prevent leakage and ensure stability.
  • Step 10: Ligation of Common Bile Duct - The common bile duct is ligated to prevent bile leakage and prepare the pancreas for transplantation.
  • Step 11: Ligation of Middle Colic Vessels - The middle colic vessels are ligated at the base of the transverse mesocolon to control blood flow during the procedure.
  • Step 12: Ligation of Superior Mesenteric Vessels - The superior mesenteric vessels are ligated at the root of the small bowel mesentery, ensuring that the pancreas has adequate blood supply.
  • Step 13: Construction of Y-Graft - A Y-graft is constructed by suturing the external and internal iliac arteries to the superior mesenteric artery, facilitating proper arterial supply to the pancreas.
  • Step 14: Final Preservation - The pancreas is maintained on ice and bathed in cold preservation solution until the recipient is prepared for transplant, ensuring its viability until the moment of transplantation.

3. Post-Procedure

After the backbench preparation of the pancreas allograft, the organ is kept on ice and in cold preservation solution until the recipient is ready for transplantation. It is crucial to monitor the condition of the pancreas during this time to ensure that it remains viable for successful implantation. The surgical team must be prepared to proceed with the transplantation as soon as the recipient is ready, minimizing the time the pancreas is outside of a controlled environment to enhance the chances of a successful transplant outcome.

Short Descr PREP DONOR PANCREAS
Medium Descr BKBENCH PREPJ CADAVER DONOR PANCREAS ALLOGRAFT
Long Descr Backbench standard preparation of cadaver donor pancreas allograft prior to transplantation, including dissection of allograft from surrounding soft tissues, splenectomy, duodenotomy, ligation of bile duct, ligation of mesenteric vessels, and Y-graft arterial anastomoses from iliac artery to superior mesenteric artery and to splenic artery
Status Code Carriers Price the Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 2 - Payment restriction for assistants at surgery does not apply to this procedure...
Co-Surgeons (62) 1 - Co-surgeons could be paid, though supporting documentation is required...
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Inpatient Procedures, not paid under OPPS
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P1G - Major procedure - Other
MUE 1
CCS Clinical Classification 176 - Other organ transplantation
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
62 Two surgeons: when 2 surgeons work together as primary surgeons performing distinct part(s) of a procedure, each surgeon should report his/her distinct operative work by adding modifier 62 to the procedure code and any associated add-on code(s) for that procedure as long as both surgeons continue to work together as primary surgeons. each surgeon should report the co-surgery once using the same procedure code. if additional procedure(s) (including add-on procedure(s) are performed during the same surgical session, separate code(s) may also be reported with modifier 62 added. note: if a co-surgeon acts as an assistant in the performance of additional procedure(s), other than those reported with the modifier 62, during the same surgical session, those services may be reported using separate procedure code(s) with modifier 80 or modifier 82 added, as appropriate.
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
CR Catastrophe/disaster related
GC This service has been performed in part by a resident under the direction of a teaching physician
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
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Notes
2005-01-01 Added First appearance in code book in 2005.
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