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Official Description

Sclerotherapy of a fluid collection (eg, lymphocele, cyst, or seroma), percutaneous, including contrast injection(s), sclerosant injection(s), diagnostic study, imaging guidance (eg, ultrasound, fluoroscopy) and radiological supervision and interpretation when performed

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 49185 involves sclerotherapy, which is a minimally invasive technique used to treat fluid collections such as lymphoceles, cysts, or seromas. During this procedure, a chemical agent known as a sclerosant is injected into the fluid-filled cavity to induce inflammatory fibrosis of the lesion wall. This process helps to prevent the re-accumulation of fluid within the cavity. The procedure begins with the insertion of a small-bore needle through the skin into the lesion, followed by the placement of a pigtail catheter. This catheter allows for the aspiration of the fluid, which is then measured and sent for laboratory analysis, including tests such as Gram stain, culture, and cytology. To ensure the safety and effectiveness of the sclerotherapy, diluted contrast dye is injected through the catheter and monitored using imaging techniques like fluoroscopy. This step is crucial to rule out any potential communication between the cyst or fluid cavity and surrounding structures, such as the peritoneum, blood vessels, biliary system, or renal collecting system. If any communication is detected, the injection of the sclerosant is contraindicated. Once it is confirmed that there is no leakage, approximately 50% of the aspirated fluid volume is replaced with the sclerosant, with ethanol being the most commonly used agent. Other sclerosants may include bismuth, povidone-iodine, tetracycline, bleomycin, hypertonic saline, ethanolamine oleate, and acetic acid. The patient's position is adjusted to ensure that the sclerosant makes contact with the entire cyst wall. After allowing the sclerosant to act for a minimum of 20 minutes, it is then removed via aspiration. The catheter may be connected to bulb suction, and imaging studies such as ultrasound or computed tomography are performed to confirm the complete evacuation of the sclerosant. Depending on the treatment plan, the catheter may be removed immediately or left in place for potential future treatments. CPT® Code 49185 encompasses all necessary imaging guidance and the associated supervision and interpretation required during the sclerotherapy procedure.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The sclerotherapy procedure described by CPT® Code 49185 is indicated for the treatment of various fluid collections. The following conditions are explicitly mentioned as suitable for this procedure:

  • Lymphocele A lymphocele is a collection of lymphatic fluid that can occur after surgical procedures, particularly those involving lymph node removal.
  • Cyst Cysts are closed sac-like structures that can contain fluid, air, or other substances, and may require intervention if they cause discomfort or complications.
  • Seroma A seroma is a collection of serous fluid that can develop after surgery or injury, often requiring drainage to alleviate symptoms.

2. Procedure

The sclerotherapy procedure involves several critical steps to ensure effective treatment of the fluid collection. Each step is detailed as follows:

  • Step 1: Preparation and Access The procedure begins with the patient being positioned appropriately, and the skin over the fluid collection is prepared and sterilized. A small-bore needle is then inserted through the skin into the lesion to gain access to the fluid collection.
  • Step 2: Aspiration Once access is achieved, a pigtail catheter is inserted over the needle. The fluid within the cavity is aspirated and measured to assess the volume. A sample of the aspirated fluid is sent for laboratory analysis, which may include Gram stain, culture, and cytology to evaluate for infection or other abnormalities.
  • Step 3: Imaging Guidance After aspiration, diluted contrast dye is injected through the catheter. This step is crucial as it allows for imaging guidance using fluoroscopy to visualize the fluid collection and rule out any communication with surrounding structures such as the peritoneum, blood vessels, biliary system, or renal collecting system. This assessment is vital to ensure that the sclerosant can be safely injected.
  • Step 4: Sclerosant Injection If no leakage is detected, approximately 50% of the aspirated volume is replaced with the sclerosant, commonly ethanol, although other agents may be used. The patient's position is rotated to ensure that the sclerosant comes into contact with the entire cyst wall, maximizing its effectiveness.
  • Step 5: Sclerosant Removal After allowing the sclerosant to act for a minimum of 20 minutes, it is removed via aspiration. The catheter may then be connected to bulb suction to facilitate the removal process.
  • Step 6: Final Imaging Following the aspiration of the sclerosant, imaging studies such as ultrasound or computed tomography are performed to confirm the complete evacuation of the sclerosant from the cavity.
  • Step 7: Catheter Management Depending on the treatment plan, the catheter may be removed immediately after the procedure or left in place if additional treatments are anticipated.

3. Post-Procedure

Post-procedure care following sclerotherapy involves monitoring the patient for any immediate complications and ensuring proper recovery. Patients may be advised to rest and avoid strenuous activities for a specified period. Follow-up appointments may be scheduled to assess the effectiveness of the treatment and to determine if further interventions are necessary. It is also important to monitor for any signs of infection or adverse reactions to the sclerosant used during the procedure. Documentation of the procedure, including imaging results and any laboratory findings, should be completed to ensure comprehensive patient care and compliance with medical coding requirements.

Short Descr SCLEROTX FLUID COLLECTION
Medium Descr SCLEROTHERAPY FLUID COLLECTION PRQ W/IMG GID
Long Descr Sclerotherapy of a fluid collection (eg, lymphocele, cyst, or seroma), percutaneous, including contrast injection(s), sclerosant injection(s), diagnostic study, imaging guidance (eg, ultrasound, fluoroscopy) and radiological supervision and interpretation when performed
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P5E - Ambulatory procedures - other
MUE 2
GC This service has been performed in part by a resident under the direction of a teaching physician
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CR Catastrophe/disaster related
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
LT Left side (used to identify procedures performed on the left side of the body)
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
RT Right side (used to identify procedures performed on the right side of the body)
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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2016-01-01 Added Added
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