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Official Description

Ablation, renal tumor(s), unilateral, percutaneous, cryotherapy

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 50593 involves the ablation of one or more renal tumors through a technique known as cryotherapy, which is performed unilaterally and via a percutaneous approach. In this context, "ablation" refers to the process of destroying tumor tissue, and "cryotherapy" specifically utilizes extreme cold to achieve this destruction. The procedure is guided by imaging techniques such as ultrasound, computed tomography (CT), or magnetic resonance imaging (MRI), which are separately reportable. These imaging modalities are essential for accurately identifying the tumor(s) and ensuring precise placement of the cryotherapy probes. During the procedure, multiple probes may be necessary to ensure that the entire tumor is effectively destroyed while also providing adequate margins of healthy tissue. The entry points for these probes are carefully determined, and small incisions are made to facilitate their insertion. The probes are then guided into the center of the tumor(s) using the aforementioned imaging techniques, with particular attention paid to avoiding surrounding organs and major blood vessels. Once the probes are correctly positioned, the cryoablation unit is activated, and the probes are filled with argon gas, which allows for rapid freezing of the tumor tissue at temperatures that can reach as low as -100 degrees centigrade. Following the freezing phase, a thawing cycle is initiated by replacing the argon gas with helium, which is crucial for the ablation process. Throughout the procedure, imaging guidance continues to be utilized to monitor the formation of the cryoablation sphere, commonly referred to as an "ice ball," and to assess the extent of tumor necrosis. Typically, complete destruction of the tumor requires two freeze/thaw cycles. Upon completion of the treatment, the probes are carefully withdrawn, the skin incisions are cleansed, and a dressing is applied to the site to promote healing.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure described by CPT® Code 50593 is indicated for the treatment of renal tumors. The specific indications for performing percutaneous cryotherapy include:

  • Renal Tumors One or more tumors located in the kidney that require ablation to prevent further growth or complications.

2. Procedure

The procedure for percutaneous cryotherapy of renal tumors involves several critical steps to ensure effective treatment.

  • Step 1: Imaging Guidance Initially, imaging techniques such as ultrasound, CT, or MRI are employed to accurately locate the renal tumor(s). This imaging is essential for planning the procedure and ensuring precise probe placement.
  • Step 2: Incision and Probe Placement After identifying the tumor(s), the physician determines the optimal entry sites for the cryotherapy probes. Small incisions are made at these sites to facilitate the insertion of the probes. Using the previously obtained imaging guidance, the probes are carefully inserted into the center of the tumor(s), ensuring that surrounding organs and major blood vessels are avoided.
  • Step 3: Activation of Cryoablation Unit Once the probes are in place, the cryoablation unit is activated. The probes are filled with argon gas, which allows for rapid freezing of the tumor tissue at extremely low temperatures, reaching as low as -100 degrees centigrade.
  • Step 4: Freeze/Thaw Cycles The freezing process is followed by a thawing cycle, which is initiated by replacing the argon gas with helium. This cycle is crucial for the effective ablation of the tumor. Typically, two freeze/thaw cycles are required to achieve complete tumor destruction.
  • Step 5: Monitoring and Completion Throughout the procedure, imaging guidance is used to monitor the creation of the cryoablation sphere, or "ice ball," and to assess the extent of tumor necrosis. After confirming that the tumor has been adequately ablated, the probes are withdrawn from the body.
  • Step 6: Post-Procedure Care Following the removal of the probes, the skin incisions are cleansed, and a dressing is applied to the site to promote healing and prevent infection.

3. Post-Procedure

After the completion of the cryotherapy procedure, patients are typically monitored for any immediate complications. The entry sites are cleaned, and a dressing is applied to protect the incisions. Patients may experience some discomfort or pain at the site of the procedure, which can be managed with appropriate analgesics. Follow-up imaging may be required to assess the effectiveness of the treatment and ensure that the tumor has been completely ablated. Additionally, patients should be advised on signs of infection or other complications that may require further medical attention.

Short Descr PERC CRYO ABLATE RENAL TUM
Medium Descr ABLATION RENAL TUMOR UNILATERAL PERQ CRYOTHERAPY
Long Descr Ablation, renal tumor(s), unilateral, percutaneous, cryotherapy
Status Code Active Code
Global Days 010 - Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 1 - 150% payment adjustment for bilateral procedures applies.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 2 - Payment restriction for assistants at surgery does not apply to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Device-intensive procedure added to ASC list in CY 2008 or later; paid at adjusted rate.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P6C - Minor procedures - other (Medicare fee schedule)
MUE 1
CCS Clinical Classification 112 - Other OR therapeutic procedures of urinary tract
RT Right side (used to identify procedures performed on the right side of the body)
LT Left side (used to identify procedures performed on the left side of the body)
GC This service has been performed in part by a resident under the direction of a teaching physician
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
50 Bilateral procedure: unless otherwise identified in the listings, bilateral procedures that are performed at the same session, should be identified by adding modifier 50 to the appropriate 5 digit code. note: this modifier should not be appended to designated "add-on" codes (see appendix d).
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CR Catastrophe/disaster related
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
GZ Item or service expected to be denied as not reasonable and necessary
MG The order for this service does not have applicable appropriate use criteria in the qualified clinical decision support mechanism consulted by the ordering professional
MH Unknown if ordering professional consulted a clinical decision support mechanism for this service, related information was not provided to the furnishing professional or provider
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
QQ Ordering professional consulted a qualified clinical decision support mechanism for this service and the related data was provided to the furnishing professional
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
2017-01-01 Changed Moderate (Conscious) Sedation flag removed. See new Moderate Sedation category.
2008-01-01 Added First appearance in code book in 2008.
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