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Official Description

Biopsies, prostate, needle, transperineal, stereotactic template guided saturation sampling, including imaging guidance

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

A transperineal needle biopsy of the prostate is a medical procedure that involves the extraction of tissue samples from the prostate gland for diagnostic purposes. This procedure is performed using a technique known as stereotactic template-guided saturation sampling, which ensures precise targeting of the prostate tissue. The process begins with the use of transrectal ultrasound (TRUS) to visualize the prostate and guide the biopsy needle accurately. A stereotactic template is then employed, which is a specialized device that helps in positioning the prostate on an implant grid. This grid is systematically divided into six or more sections, allowing for comprehensive sampling of the prostate tissue. A linear probe, equipped with a needle guidance attachment, is utilized to facilitate the collection of tissue samples from each designated section of the prostate. During the procedure, multiple tissue cores—potentially up to 60—are harvested and placed into separate specimen jars, each corresponding to the specific section from which the sample was taken. These samples are subsequently sent to a laboratory for pathology analysis, where they are examined for any signs of disease, such as cancer. This method of biopsy is particularly beneficial as it maximizes the chances of detecting abnormalities within the prostate by ensuring thorough sampling across multiple areas of the gland.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The transperineal needle biopsy of the prostate using stereotactic template-guided saturation sampling is indicated for the following conditions:

  • Prostate Cancer Screening This procedure is often performed when there is a suspicion of prostate cancer based on elevated prostate-specific antigen (PSA) levels or abnormal findings during a digital rectal examination (DRE).
  • Diagnosis of Prostate Abnormalities It is indicated for patients presenting with symptoms suggestive of prostate disease, such as urinary difficulties, pelvic pain, or other related symptoms.
  • Monitoring of Known Prostate Conditions This biopsy technique may be utilized for patients with a history of prostate conditions who require further evaluation to assess the progression or regression of the disease.

2. Procedure

The procedure for performing a transperineal needle biopsy of the prostate involves several critical steps to ensure accuracy and safety:

  • Step 1: Patient Preparation The patient is positioned appropriately, typically in a supine position, to allow optimal access to the perineal area. Local anesthesia may be administered to minimize discomfort during the procedure.
  • Step 2: Imaging Guidance Setup Transrectal ultrasound (TRUS) is utilized to visualize the prostate gland. The imaging helps in guiding the biopsy needle accurately to the targeted areas of the prostate.
  • Step 3: Stereotactic Template Application A stereotactic template is placed over the perineum, aligning it with the prostate as visualized by the TRUS. This template is crucial for ensuring that the biopsy needle is directed to the correct locations within the prostate.
  • Step 4: Tissue Sampling Using a linear probe equipped with a needle guidance attachment, the physician obtains tissue cores from the prostate. The implant grid divides the prostate into six or more sections, allowing for systematic sampling. Each section is targeted to ensure comprehensive coverage of the prostate tissue.
  • Step 5: Specimen Collection The collected tissue cores, which may number up to 60, are placed into separate specimen jars. Each jar is labeled according to the section from which the sample was taken, ensuring accurate identification for subsequent analysis.
  • Step 6: Post-Procedure Care After the biopsy, the patient is monitored for any immediate complications, and instructions for post-procedure care are provided, including signs of potential complications to watch for.

3. Post-Procedure

Following the transperineal needle biopsy, patients are typically advised to rest and may experience some discomfort or minor bleeding at the biopsy site. It is essential to monitor for any signs of complications, such as significant bleeding, infection, or urinary difficulties. Patients are usually instructed to avoid strenuous activities for a short period and to follow up with their healthcare provider to discuss the results of the pathology analysis. The tissue samples collected will be sent to a laboratory for examination, and the results will guide further management and treatment options based on the findings.

Short Descr PROSTATE SATURATION SAMPLING
Medium Descr BX PROSTATE STRTCTC SATURATION SAMPLING IMG GID
Long Descr Biopsies, prostate, needle, transperineal, stereotactic template guided saturation sampling, including imaging guidance
Status Code Active Code
Global Days 010 - Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 2 - Payment restriction for assistants at surgery does not apply to this procedure...
Co-Surgeons (62) 1 - Co-surgeons could be paid, though supporting documentation is required...
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Non office-based surgical procedure added in CY 2008 or later; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P6C - Minor procedures - other (Medicare fee schedule)
MUE 1
CCS Clinical Classification 116 - Diagnostic procedures, male genital
GC This service has been performed in part by a resident under the direction of a teaching physician
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
SG Ambulatory surgical center (asc) facility service
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CR Catastrophe/disaster related
GZ Item or service expected to be denied as not reasonable and necessary
KX Requirements specified in the medical policy have been met
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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2009-01-01 Added -
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