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Official Description

Colposcopy of the cervix including upper/adjacent vagina;

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 57452 involves a colposcopy of the cervix and the upper adjacent vagina. A colposcopy is a diagnostic procedure that utilizes a specialized instrument known as a colposcope, which resembles a pair of binoculars mounted on a stand and equipped with a light source. This instrument is designed to magnify the tissues of the cervix and upper adjacent vagina, thereby enhancing the physician's ability to visualize any abnormal tissue that may be present. During the procedure, the colposcope is positioned at the vaginal opening, and a speculum is inserted into the vagina to gently separate the vaginal walls, facilitating a clear view of the cervix and the upper adjacent vaginal wall. The examination is conducted under varying magnifications, typically two or three, to ensure a thorough assessment of the cervical and vaginal tissues. To improve the visibility of abnormal cells, acetic acid is applied to the area. This application helps to highlight any irregularities in the cells. Following this, different-colored filters are utilized to observe blood vessels and identify any abnormal patterns in blood vessel formation. Additionally, an iodine solution is applied to stain the cells, where normal cells will typically take on a dark-brown color. Areas that do not exhibit this staining, as well as those previously identified with abnormal blood vessel patterns, are targeted for biopsy. If necessary, an endocervical curettage (ECC) may be performed, which involves scraping the cervical canal with a curet inserted into the cervix to collect tissue samples for further examination. It is important to note that CPT® Code 57452 is specifically designated for colposcopy procedures without biopsy or ECC, while other codes are available for procedures that include these additional interventions.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The colposcopy procedure described by CPT® Code 57452 is indicated for various clinical scenarios where there is a need for detailed examination of the cervix and upper adjacent vagina. The following conditions may warrant the performance of this procedure:

  • Abnormal Pap Smear Results - Patients with atypical squamous cells or other abnormal findings on cervical cytology may require colposcopy for further evaluation.
  • Visible Lesions - The presence of visible lesions or abnormalities on the cervix or upper vagina that need to be assessed for potential malignancy.
  • Follow-Up of Previous Abnormalities - Patients with a history of cervical dysplasia or other cervical abnormalities may undergo colposcopy for monitoring and assessment of any changes.
  • Human Papillomavirus (HPV) Infection - Women with high-risk HPV types may be referred for colposcopy to evaluate the cervix for any precancerous changes.

2. Procedure

The colposcopy procedure involves several key steps to ensure a thorough examination of the cervix and upper adjacent vagina. The following procedural steps are performed:

  • Step 1: Positioning the Colposcope - The colposcope is positioned at the vaginal opening to provide a clear view of the cervix and upper adjacent vagina. This positioning is crucial for effective visualization during the examination.
  • Step 2: Insertion of the Speculum - A speculum is inserted into the vagina to gently separate the vaginal walls. This allows the physician to have unobstructed access to the cervix and upper adjacent vaginal wall for examination.
  • Step 3: Examination Under Magnification - The cervix and upper adjacent vagina are examined under two or three different magnifications. This step is essential for identifying any abnormal tissue or lesions that may not be visible to the naked eye.
  • Step 4: Application of Acetic Acid - Acetic acid is applied to the cervix and upper adjacent vagina to enhance the visualization of abnormal cells. The application of acetic acid helps to highlight areas of dysplasia or other abnormalities.
  • Step 5: Use of Colored Filters - Different-colored filters are utilized to visualize blood vessels and identify any abnormal blood vessel patterns. This step aids in the assessment of vascular changes associated with abnormal tissue.
  • Step 6: Application of Iodine Solution - An iodine solution is painted onto the cervix and upper adjacent vagina. Normal cells will stain a dark-brown color, while areas that do not stain are indicative of potential abnormalities.
  • Step 7: Biopsy of Abnormal Areas - Any areas that do not stain with iodine, as well as those previously identified with abnormal blood vessel patterns, are biopsied for further pathological evaluation.
  • Step 8: Endocervical Curettage (ECC) - If indicated, an endocervical curettage is performed by scraping the cervical canal with a curet inserted into the cervix. This step is essential for obtaining tissue samples from the cervical canal.

3. Post-Procedure

After the colposcopy procedure, patients may experience some mild discomfort or spotting. It is important for patients to be informed about potential post-procedure symptoms and to follow any specific aftercare instructions provided by the physician. Patients should be advised to monitor for any unusual symptoms, such as heavy bleeding or severe pain, and to contact their healthcare provider if these occur. Follow-up appointments may be scheduled to discuss biopsy results and any further management that may be necessary based on the findings of the colposcopy.

Short Descr EXAM OF CERVIX W/SCOPE
Medium Descr COLPOSCOPY CERVIX UPPER/ADJACENT VAGINA
Long Descr Colposcopy of the cervix including upper/adjacent vagina;
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Multiple Reduction Applies
ASC Payment Indicator Office-based surgical procedure added to ASC list in CY 2008 or later with MPFS nonfacility PE RVUs; payment based on MPFS nonfacility PE RVUs.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P8I - Endoscopy - other
MUE 1
CCS Clinical Classification 130 - Other diagnostic procedures, female organs

This is a primary code that can be used with these additional add-on codes.

57465 Female Edit Add-on Code MPFS Status: Active Code APC N Computer-aided mapping of cervix uteri during colposcopy, including optical dynamic spectral imaging and algorithmic quantification of the acetowhitening effect (List separately in addition to code for primary procedure)
58110 Female Edit Addon Code MPFS Status: Active Code APC N ASC N1 CPT Assistant Article Illustration for Code Endometrial sampling (biopsy) performed in conjunction with colposcopy (List separately in addition to code for primary procedure)
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
74 Discontinued out-patient hospital/ambulatory surgery center (asc) procedure after administration of anesthesia: due to extenuating circumstances or those that threaten the well being of the patient, the physician may terminate a surgical or diagnostic procedure after the administration of anesthesia (local, regional block(s), general) or after the procedure was started (incision made, intubation started, scope inserted, etc). under these circumstances, the procedure started but terminated can be reported by its usual procedure number and the addition of modifier 74. note: the elective cancellation of a service prior to the administration of anesthesia and/or surgical preparation of the patient should not be reported. for physician reporting of a discontinued procedure, see modifier 53.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
95 Synchronous telemedicine service rendered via a real-time interactive audio and video telecommunications system: synchronous telemedicine service is defined as a real-time interaction between a physician or other qualified health care professional and a patient who is located at a distant site from the physician or other qualified health care professional. the totality of the communication of information exchanged between the physician or other qualified health care professional and the patient during the course of the synchronous telemedicine service must be of an amount and nature that would be sufficient to meet the key components and/or requirements of the same service when rendered via a face-to-face interaction. modifier 95 may only be appended to the services listed in appendix p. appendix p is the list of cpt codes for services that are typically performed face-to-face, but may be rendered via a real-time (synchronous) interactive audio and video telecommunications system.
AG Primary physician
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CR Catastrophe/disaster related
GA Waiver of liability statement issued as required by payer policy, individual case
GC This service has been performed in part by a resident under the direction of a teaching physician
GW Service not related to the hospice patient's terminal condition
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
X1 Continuous/broad services: for reporting services by clinicians, who provide the principal care for a patient, with no planned endpoint of the relationship; services in this category represent comprehensive care, dealing with the entire scope of patient problems, either directly or in a care coordination role; reporting clinician service examples include, but are not limited to: primary care, and clinicians providing comprehensive care to patients in addition to specialty care
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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2010-01-01 Changed Code description changed.
2003-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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