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Official Description

Gamete, zygote, or embryo intrafallopian transfer, any method

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 58976 refers to the procedure of gamete, zygote, or embryo intrafallopian transfer, which encompasses the transfer of reproductive cells or early-stage embryos into a patient's fallopian tubes. This procedure is typically performed using one of two primary methods: Gamete Intrafallopian Transfer (GIFT) or Zygote Intrafallopian Transfer (ZIFT). In GIFT, both the egg and sperm are collected in a laboratory environment and subsequently injected into the fallopian tube through a catheter, allowing for natural fertilization to occur within the body. Conversely, ZIFT involves the transfer of a fertilized egg, or zygote, which has already undergone fertilization in the laboratory. This zygote is then aspirated into a catheter and placed into the fallopian tube. Both GIFT and ZIFT can be executed using minimally invasive techniques, such as laparoscopy or hysteroscopy, which involve the use of specialized instruments to access the reproductive organs through small incisions or the vaginal canal. This procedure is significant in assisted reproductive technology, providing an alternative approach for individuals or couples facing challenges with conception.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure of gamete, zygote, or embryo intrafallopian transfer (CPT® Code 58976) is indicated for various reproductive challenges and conditions. The following are the explicitly provided indications for performing this procedure:

  • Infertility The procedure is often indicated for couples experiencing infertility, particularly when other assisted reproductive technologies have not been successful.
  • Blocked Fallopian Tubes In cases where the fallopian tubes are blocked, GIFT or ZIFT may be utilized to bypass the blockage and facilitate fertilization and implantation.
  • Unexplained Infertility For couples with no identifiable cause of infertility, this procedure may be considered as a potential solution.
  • Previous Fertility Treatments Patients who have undergone previous fertility treatments without success may be candidates for this procedure as an alternative approach.

2. Procedure

The procedure of gamete, zygote, or embryo intrafallopian transfer involves several critical steps that ensure the successful transfer of reproductive cells into the fallopian tubes. The following outlines the procedural steps:

  • Step 1: Preparation Prior to the procedure, the patient undergoes a thorough evaluation, including hormonal assessments and imaging studies, to determine the best approach for the transfer. The physician will also discuss the procedure, potential risks, and expected outcomes with the patient.
  • Step 2: Oocyte Retrieval In the case of GIFT, oocytes (eggs) are retrieved from the ovaries using a transvaginal ultrasound-guided aspiration technique. This step is performed under sedation or anesthesia to ensure patient comfort.
  • Step 3: Sperm Collection Concurrently, a sperm sample is collected from the male partner or a sperm donor. The sperm is then processed in the laboratory to select the most viable sperm for fertilization.
  • Step 4: Fertilization (for ZIFT) If ZIFT is being performed, the retrieved oocytes are fertilized in the laboratory with the prepared sperm. Once fertilization occurs, the resulting zygotes are cultured for a specific period to ensure proper development.
  • Step 5: Transfer The physician uses a catheter to transfer the gametes, zygotes, or embryos into the fallopian tube. This can be done laparoscopically, where small incisions are made in the abdomen, or hysteroscopically, where the procedure is performed through the vaginal canal. The choice of method depends on the specific circumstances and physician preference.

3. Post-Procedure

After the gamete, zygote, or embryo intrafallopian transfer, patients are typically monitored for a short period to ensure there are no immediate complications. Post-procedure care may include instructions on activity restrictions, such as avoiding strenuous exercise or heavy lifting for a specified duration. Patients may also be advised to follow up with their healthcare provider to assess the success of the procedure and discuss any further steps, including potential pregnancy testing. It is essential for patients to adhere to any prescribed medications, such as hormonal support, to optimize the chances of successful implantation and pregnancy.

Short Descr TRANSFER OF EMBRYO
Medium Descr GAMETE ZYGOTE/EMBRYO FALLOPIAN TRANSFER ANY METH
Long Descr Gamete, zygote, or embryo intrafallopian transfer, any method
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 2 - Payment restriction for assistants at surgery does not apply to this procedure...
Co-Surgeons (62) 1 - Co-surgeons could be paid, though supporting documentation is required...
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Multiple Reduction Applies
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P5E - Ambulatory procedures - other
MUE 2
CCS Clinical Classification 132 - Other OR therapeutic procedures, female organs
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