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Official Description

Biopsy thyroid, percutaneous core needle

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 60100 refers to a percutaneous core needle biopsy of the thyroid gland. This procedure is performed to obtain a tissue sample from the thyroid, which is essential for diagnosing various thyroid conditions, including nodules, hyperplasia, or malignancies. During the biopsy, imaging guidance may be utilized to ensure accurate needle placement, although this guidance is reported separately. The procedure begins with the cleansing of the skin over the thyroid area, followed by the administration of a local anesthetic to minimize discomfort for the patient. A large-bore needle is then carefully inserted into the thyroid gland to extract a tissue sample. It is important to note that the needle may be inserted multiple times at different sites within the thyroid to ensure that an adequate and representative tissue sample is collected. Once obtained, the tissue sample is sent to a laboratory for histological evaluation, which is a critical step in determining the nature of any abnormalities present in the thyroid tissue.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The percutaneous core needle biopsy of the thyroid (CPT® Code 60100) is indicated for various clinical scenarios, particularly when there is a need to evaluate thyroid nodules or other abnormalities. The following conditions may warrant this procedure:

  • Thyroid Nodules - The presence of one or more nodules in the thyroid gland that require further investigation to determine if they are benign or malignant.
  • Hyperplasia - Conditions characterized by an increase in the number of cells in the thyroid, which may necessitate a biopsy to rule out malignancy.
  • Suspicious Imaging Findings - Abnormalities detected through imaging studies, such as ultrasound, that raise concerns about potential thyroid cancer.

2. Procedure

The procedure for a percutaneous core needle biopsy of the thyroid involves several critical steps to ensure accurate tissue sampling. The first step is the preparation of the patient, which includes cleansing the skin over the thyroid gland to reduce the risk of infection. Following this, a local anesthetic is administered to the patient to minimize discomfort during the procedure. Once the area is adequately anesthetized, a large-bore needle is introduced into the thyroid gland. The physician may pass the needle multiple times into different sites within the thyroid to obtain sufficient tissue samples. This technique is essential to ensure that the samples collected are representative of the thyroid tissue and can provide the necessary information for diagnosis. After the tissue samples are obtained, they are sent to a laboratory for histological evaluation, where they will be examined microscopically to identify any pathological changes.

3. Post-Procedure

After the percutaneous core needle biopsy of the thyroid, patients are typically monitored for any immediate complications, such as bleeding or discomfort at the biopsy site. It is common for patients to experience some soreness or swelling in the area, which usually resolves within a few days. Patients may be advised to avoid strenuous activities for a short period following the procedure. Additionally, the results of the histological evaluation will be communicated to the patient and their healthcare provider, guiding further management based on the findings. Follow-up appointments may be scheduled to discuss the results and any necessary next steps in treatment or monitoring.

Short Descr BIOPSY OF THYROID
Medium Descr BIOPSY THYROID PERCUTANEOUS CORE NEEDLE
Long Descr Biopsy thyroid, percutaneous core needle
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Multiple Reduction Applies
ASC Payment Indicator Office-based surgical procedure added to ASC list in CY 2008 or later with MPFS nonfacility PE RVUs; payment based on MPFS nonfacility PE RVUs.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P6C - Minor procedures - other (Medicare fee schedule)
MUE 3
CCS Clinical Classification 11 - Diagnostic endocrine procedures

This is a primary code that can be used with these additional add-on codes.

77002 CPT Add On MPFS Status: Active Code APC N ASC N1 Physician Quality Reporting CPT Assistant Article Fluoroscopic guidance for needle placement (eg, biopsy, aspiration, injection, localization device) (List separately in addition to code for primary procedure)
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
GC This service has been performed in part by a resident under the direction of a teaching physician
LT Left side (used to identify procedures performed on the left side of the body)
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
AG Primary physician
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CR Catastrophe/disaster related
GA Waiver of liability statement issued as required by payer policy, individual case
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
RT Right side (used to identify procedures performed on the right side of the body)
SG Ambulatory surgical center (asc) facility service
X3 Episodic/broad services: for reporting services by clinicians who have broad responsibility for the comprehensive needs of the patient that is limited to a defined period and circumstance such as a hospitalization; reporting clinician service examples include but are not limited to the hospitalist's services rendered providing comprehensive and general care to a patient while admitted to the hospital
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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Pre-1990 Added Code added.
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