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Official Description

Adrenalectomy, partial or complete, or exploration of adrenal gland with or without biopsy, transabdominal, lumbar or dorsal (separate procedure); with excision of adjacent retroperitoneal tumor

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The adrenal glands are vital endocrine organs situated atop each kidney, responsible for producing a variety of hormones that regulate numerous physiological processes. These hormones include epinephrine and norepinephrine, which are critical for the body's stress response, as well as androgens, estrogens, aldosterone, and cortisol, which play significant roles in metabolism, immune response, and blood pressure regulation. An adrenalectomy, whether partial or complete, involves the surgical removal of these glands and may also include exploration and biopsy of the adrenal gland. This procedure is typically indicated in cases of adrenal gland enlargement or the presence of tumors, which can lead to excessive hormone production and resultant hormonal imbalances. The surgical approach to the adrenal gland can be through various incisions, including anterior or posterior subcostal, midline abdominal, or flank incisions. During the procedure, the surgeon dissects the overlying tissues to expose the adrenal gland. If exploration and biopsy are performed, the gland is meticulously examined, and a tissue sample is collected for further analysis. In cases where excision is necessary, the blood vessels supplying the gland are carefully ligated and divided, allowing for the complete removal of the adrenal gland along with any adjacent retroperitoneal tumors, if present. The surgical site is then irrigated with sterile saline, and the incision is closed in layers to promote optimal healing. It is important to differentiate between CPT® codes 60540 and 60545, as the latter is specifically used when an adjacent retroperitoneal tumor is excised in conjunction with the adrenal gland procedure.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

Adrenalectomy, whether partial or complete, is performed for specific indications related to the adrenal glands. The following conditions may warrant this surgical intervention:

  • Adrenal Tumors Tumors present in the adrenal glands that may be benign or malignant, often leading to excessive hormone production.
  • Adrenal Hyperplasia Enlargement of the adrenal glands, which can disrupt normal hormone levels and lead to various health issues.
  • Hormonal Imbalances Conditions resulting from overproduction of hormones such as cortisol, aldosterone, or catecholamines, causing significant physiological disturbances.
  • Adrenal Cysts Fluid-filled sacs that can develop in the adrenal glands, potentially causing discomfort or hormonal issues.

2. Procedure

The adrenalectomy procedure involves several critical steps to ensure the safe and effective removal of the adrenal gland and any adjacent tumors. The following outlines the procedural steps:

  • Step 1: Anesthesia Administration The patient is placed under general anesthesia to ensure comfort and immobility during the procedure.
  • Step 2: Incision The surgeon makes an incision, which may be anterior or posterior subcostal, midline abdominal, or flank, depending on the approach deemed most appropriate for the patient's anatomy and the surgeon's preference.
  • Step 3: Tissue Dissection Overlying tissues are carefully dissected to expose the adrenal gland. This step requires precision to avoid damaging surrounding structures.
  • Step 4: Exploration and Biopsy If indicated, the adrenal gland is inspected for abnormalities, and a biopsy may be performed to obtain tissue samples for pathological examination.
  • Step 5: Excision of the Adrenal Gland If excision is necessary, the blood vessels supplying the adrenal gland are ligated and divided. The gland is then meticulously dissected free from surrounding tissues.
  • Step 6: Tumor Excision If an adjacent retroperitoneal tumor is present, it is excised along with a wide margin of normal tissue to ensure complete removal of all tumor cells.
  • Step 7: Wound Irrigation and Closure The surgical site is irrigated with sterile saline to reduce the risk of infection, and the incision is closed in layers to promote healing.

3. Post-Procedure

After the adrenalectomy, patients are typically monitored in a recovery area for any immediate complications. Post-operative care may include pain management, monitoring for signs of infection, and ensuring proper wound healing. Patients may also require hormonal assessments and adjustments, especially if a significant portion of the adrenal gland was removed. Follow-up appointments are essential to evaluate recovery and manage any potential hormonal imbalances resulting from the surgery. The expected recovery time can vary based on the extent of the procedure and the patient's overall health, but most individuals can anticipate a gradual return to normal activities within several weeks.

Short Descr EXPLORE ADRENAL GLAND
Medium Descr ADRENALECTOMY EXPL W/EXC RETROPERTINEAL TUMOR
Long Descr Adrenalectomy, partial or complete, or exploration of adrenal gland with or without biopsy, transabdominal, lumbar or dorsal (separate procedure); with excision of adjacent retroperitoneal tumor
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 1 - 150% payment adjustment for bilateral procedures applies.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 2 - Payment restriction for assistants at surgery does not apply to this procedure...
Co-Surgeons (62) 1 - Co-surgeons could be paid, though supporting documentation is required...
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Inpatient Procedures, not paid under OPPS
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P1G - Major procedure - Other
MUE 1
CCS Clinical Classification 12 - Other therapeutic endocrine procedures
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
62 Two surgeons: when 2 surgeons work together as primary surgeons performing distinct part(s) of a procedure, each surgeon should report his/her distinct operative work by adding modifier 62 to the procedure code and any associated add-on code(s) for that procedure as long as both surgeons continue to work together as primary surgeons. each surgeon should report the co-surgery once using the same procedure code. if additional procedure(s) (including add-on procedure(s) are performed during the same surgical session, separate code(s) may also be reported with modifier 62 added. note: if a co-surgeon acts as an assistant in the performance of additional procedure(s), other than those reported with the modifier 62, during the same surgical session, those services may be reported using separate procedure code(s) with modifier 80 or modifier 82 added, as appropriate.
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
81 Minimum assistant surgeon: minimum surgical assistant services are identified by adding modifier 81 to the usual procedure number.
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CR Catastrophe/disaster related
GC This service has been performed in part by a resident under the direction of a teaching physician
LT Left side (used to identify procedures performed on the left side of the body)
RT Right side (used to identify procedures performed on the right side of the body)
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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