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Official Description

Craniotomy with elevation of bone flap; for partial or subtotal (functional) hemispherectomy

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 61543 involves a craniotomy with elevation of a bone flap for a partial or subtotal (functional) hemispherectomy. This surgical intervention is performed on the brain, which is anatomically divided into two cerebral hemispheres: the right and left. Each hemisphere consists of an outer layer known as the cerebral cortex, which is primarily composed of grey matter, and an inner layer of white matter. The two hemispheres are interconnected by a structure called the corpus callosum, which facilitates communication between them. In a functional hemispherectomy, a portion of the affected hemisphere is surgically removed, and the remaining nerve fibers, including those of the corpus callosum, are transected. This procedure is typically indicated for patients with severe epilepsy or other neurological conditions that affect one hemisphere of the brain. The deeper structures of the brain, such as the basal ganglia, thalamus, and brain stem, remain intact during this operation. The surgical approach involves making a long incision in the scalp, creating a scalp flap, and drilling burr holes to access the skull. The bone flap is then elevated to allow for the necessary surgical manipulation of the brain tissue. This complex procedure requires careful dissection and the use of specialized instruments to ensure the precise removal of the affected brain tissue while preserving critical structures.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure described by CPT® Code 61543 is indicated for specific neurological conditions that necessitate the removal of a portion of the cerebral hemisphere. The following are the primary indications for performing a partial or subtotal (functional) hemispherectomy:

  • Severe Epilepsy Patients with intractable epilepsy that is localized to one hemisphere and has not responded to medical management may benefit from this procedure to reduce seizure frequency and severity.
  • Hemispherectomy for Structural Abnormalities Conditions such as cortical dysplasia, tumors, or malformations that affect one hemisphere may warrant surgical intervention to alleviate symptoms and improve quality of life.
  • Traumatic Brain Injury In cases where significant damage to one hemisphere occurs due to trauma, a functional hemispherectomy may be performed to remove non-viable tissue and prevent further complications.

2. Procedure

The procedure for CPT® Code 61543 involves several critical steps to ensure the successful execution of a partial or subtotal (functional) hemispherectomy. The following outlines the procedural steps:

  • Step 1: Incision and Scalp Flap Creation A long skin incision is made, starting anterior to the coronal suture on the left side of the skull and extending across the midline to the right side. This incision allows for the creation of a scalp flap, which is lifted to expose the underlying skull.
  • Step 2: Drilling Burr Holes Burr holes are drilled slightly to the left of the midline to facilitate access to the skull. The bone between these burr holes is then cut using a saw or craniotome, allowing for the elevation of a bone flap.
  • Step 3: Dura Opening The dura mater, a protective membrane covering the brain, is opened in a curvilinear fashion, beginning at the sagittal sinus and retracted to expose the underlying brain tissue.
  • Step 4: Identification and Removal of Affected Hemisphere Once the affected hemisphere is exposed, the specific portion to be removed is identified, typically involving the frontal lobe and central cortex on the affected side. Using a surgical microscope, dissection is performed down to the interhemispheric fissure.
  • Step 5: Transection of Callosal Fibers The callosal fibers connecting the two hemispheres are divided using suction aspiration and bipolar coagulation. The affected portion of the cerebral hemisphere is then mobilized and removed.
  • Step 6: Severing Remaining Nerve Fibers Any remaining nerve fibers between the two hemispheres are severed, and the corpus callosum is transected to complete the disconnection between the affected hemisphere and the contralateral hemisphere.
  • Step 7: Closure After the transection is complete, the dura is closed, and the previously elevated bone flap is replaced and secured using sutures, wires, or miniplates and screws. The overlying muscle is repaired, and the galea and skin are closed in layers to complete the procedure.

3. Post-Procedure

Post-procedure care following a partial or subtotal (functional) hemispherectomy involves monitoring the patient for any complications and ensuring proper recovery. Patients may require intensive care initially to manage pain and monitor neurological status. Rehabilitation services, including physical, occupational, and speech therapy, may be necessary to aid in recovery and adaptation to changes in function. Follow-up appointments are essential to assess the surgical outcome, manage any ongoing symptoms, and adjust treatment plans as needed. The expected recovery period can vary based on individual patient factors and the extent of the surgery performed.

Short Descr REMOVAL OF BRAIN TISSUE
Medium Descr CRANIOTOMY PARTIAL/SUBTOTAL HEMISPHERECTOMY
Long Descr Craniotomy with elevation of bone flap; for partial or subtotal (functional) hemispherectomy
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 2 - Payment restriction for assistants at surgery does not apply to this procedure...
Co-Surgeons (62) 1 - Co-surgeons could be paid, though supporting documentation is required...
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Inpatient Procedures, not paid under OPPS
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P1G - Major procedure - Other
MUE 1
CCS Clinical Classification 1 - Incision and excision of CNS

This is a primary code that can be used with these additional add-on codes.

69990 Addon Code MPFS Status: Restricted APC N ASC N1 PUB 100 CPT Assistant Article 1Microsurgical techniques, requiring use of operating microscope (List separately in addition to code for primary procedure)
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
GC This service has been performed in part by a resident under the direction of a teaching physician
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2004-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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