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Official Description

Excision of neuroma; major peripheral nerve, except sciatic

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 64784 involves the excision of a neuroma from a major peripheral nerve, excluding the sciatic nerve. A neuroma is a benign growth that can develop on a nerve, often resulting in pain and discomfort. This procedure is performed to alleviate the symptoms associated with the neuroma by surgically removing the lesion. The process begins with making a skin incision directly over the neuroma's location. Following the incision, the surgeon carefully dissects the overlying soft tissues to access the neuroma. Once exposed, the neuroma is meticulously dissected from the surrounding tissue to ensure complete removal. After the neuroma is excised, the incision is then closed, completing the procedure. It is important to note that this code specifically applies to neuromas located on major peripheral nerves other than the sciatic nerve, which is addressed by a different code, CPT® 64786.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The excision of a neuroma from a major peripheral nerve is indicated for patients experiencing significant pain or discomfort due to the presence of a neuroma. The following conditions may warrant this surgical intervention:

  • Painful Neuroma The primary indication for this procedure is the presence of a painful neuroma that has not responded to conservative treatment options.
  • Neuroma Causing Functional Impairment If the neuroma is causing functional limitations or impairing the patient's ability to perform daily activities, excision may be necessary.
  • Diagnosis Confirmation The procedure may also be indicated when there is a need to confirm the diagnosis of a neuroma through surgical exploration.

2. Procedure

The procedure for excising a neuroma from a major peripheral nerve involves several critical steps, each essential for ensuring the successful removal of the lesion.

  • Step 1: Anesthesia Administration The procedure typically begins with the administration of local anesthesia to the area surrounding the neuroma. This step is crucial for minimizing discomfort during the surgery.
  • Step 2: Skin Incision A skin incision is made directly over the site of the neuroma. The size and length of the incision may vary depending on the neuroma's location and size.
  • Step 3: Dissection of Soft Tissues Once the incision is made, the surgeon carefully dissects the overlying soft tissues to expose the neuroma. This dissection must be performed with precision to avoid damaging surrounding nerves and tissues.
  • Step 4: Excision of the Neuroma After the neuroma is adequately exposed, the surgeon meticulously dissects it free from the surrounding tissue. This step is critical to ensure complete removal of the neuroma and to minimize the risk of recurrence.
  • Step 5: Closure of the Incision Following the excision of the neuroma, the incision is closed using sutures or other closure methods. Proper closure is essential for optimal healing and to reduce the risk of infection.

3. Post-Procedure

After the excision of the neuroma, patients may require specific post-procedure care to ensure proper healing and recovery. It is common for patients to experience some pain and swelling at the surgical site, which can be managed with prescribed pain medications. Patients are typically advised to keep the incision clean and dry, and to follow any specific wound care instructions provided by the healthcare provider. Follow-up appointments may be scheduled to monitor the healing process and to address any concerns. The expected recovery time can vary based on individual factors, but most patients can gradually resume normal activities as tolerated, following their physician's guidance.

Short Descr REMOVE NERVE LESION
Medium Descr EXC NEUROMA MAJOR PERIPHERAL NRV XCP SCIATIC
Long Descr Excision of neuroma; major peripheral nerve, except sciatic
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P5E - Ambulatory procedures - other
MUE 3
CCS Clinical Classification 9 - Other OR therapeutic nervous system procedures

This is a primary code that can be used with these additional add-on codes.

64787 Addon Code MPFS Status: Active Code APC N ASC N1 Illustration for Code Implantation of nerve end into bone or muscle (List separately in addition to neuroma excision)
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
GC This service has been performed in part by a resident under the direction of a teaching physician
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
SG Ambulatory surgical center (asc) facility service
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
AF Specialty physician
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CR Catastrophe/disaster related
F7 Right hand, third digit
LT Left side (used to identify procedures performed on the left side of the body)
RT Right side (used to identify procedures performed on the right side of the body)
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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