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Official Description

Bone marrow imaging; limited area

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

Bone marrow imaging is a non-invasive diagnostic procedure that allows healthcare professionals to visualize the functional activity of the bone marrow. This imaging technique is essential for diagnosing and staging various bone marrow disorders and infections, as well as identifying metastases from other cancers. Additionally, it plays a crucial role in evaluating the success of bone marrow transplants. Throughout a person's life, distinct changes occur in the bone marrow; at birth, the marrow is predominantly composed of hematopoietic cells, which gradually transition to adipose tissue as the individual ages. Bone marrow imaging can help assess discrepancies between the histological findings of the bone marrow and the clinical presentation of diseases, and it is also useful for monitoring the effects of radiotherapy. Furthermore, this imaging technique can detect extramedullary hematopoiesis and assist in locating the optimal site for bone marrow biopsy. The procedure typically involves drawing a blood sample, processing it to separate white blood cells (WBCs) from red blood cells (RBCs), and tagging the WBCs with a radionuclide-labeled tracer. This tracer is then injected back into the patient intravenously, and other isotopes may also be administered. Following this, imaging techniques such as Single Photon Emission Computed Tomography (SPECT) and/or Positron Emission Tomography (PET) scanning are performed at specific intervals to evaluate various conditions, including infections, metastases, bone marrow viability, aplastic anemia, and myelofibrosis. The tracers used in conjunction with SPECT and/or PET scanning can provide valuable information regarding cellular metabolism and proliferation activity within the bone marrow. Ultimately, the physician interprets the resulting Emission Computed Tomography (ECT), SPECT, CT, or PET scan images and generates a comprehensive written report detailing the findings. CPT® Code 78102 specifically pertains to bone marrow imaging of a limited area, while Code 78103 is designated for imaging multiple areas, and Code 78104 is utilized for whole-body bone marrow imaging.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The indications for performing bone marrow imaging include the following:

  • Diagnosis of Bone Marrow Disorders - Bone marrow imaging is utilized to identify and diagnose various disorders affecting the bone marrow, such as leukemia, lymphoma, and myelodysplastic syndromes.
  • Staging of Bone Marrow Disorders - This imaging technique aids in determining the extent or stage of bone marrow diseases, which is crucial for treatment planning.
  • Detection of Infections - Bone marrow imaging can help identify infections that may be localized within the bone marrow or systemic infections affecting the marrow.
  • Identification of Metastases - The procedure is effective in detecting metastatic disease that has spread to the bone marrow from other primary cancers.
  • Evaluation of Bone Marrow Transplant Success - Bone marrow imaging is used to assess the effectiveness of bone marrow transplants and monitor the engraftment of transplanted cells.
  • Monitoring Effects of Radiotherapy - This imaging can evaluate how well the bone marrow is responding to radiotherapy treatments.
  • Assessment of Aplastic Anemia and Myelofibrosis - Bone marrow imaging is beneficial in evaluating conditions such as aplastic anemia and myelofibrosis, which affect blood cell production.
  • Detection of Extramedullary Hematopoiesis - The procedure can identify areas outside the bone marrow where blood cell production is occurring, which may indicate underlying pathology.

2. Procedure

The procedure for bone marrow imaging involves several key steps, which are detailed as follows:

  • Step 1: Blood Sample Collection - A blood sample is drawn from the patient, which serves as the basis for the imaging process. This sample is essential for isolating the white blood cells (WBCs) that will be tagged for imaging.
  • Step 2: Processing the Blood Sample - The collected blood is processed to separate the WBCs from the red blood cells (RBCs). This separation is crucial as the WBCs are the cells of interest for the imaging procedure.
  • Step 3: Tagging WBCs with Radionuclide - The isolated WBCs are then tagged with a radionuclide-labeled tracer. This tagging allows the WBCs to be visualized during the imaging process, as the radionuclide emits signals that can be detected by imaging equipment.
  • Step 4: Injection of Tagged WBCs - The radionuclide-tagged WBCs are injected back into the patient intravenously. This step is critical as it allows the tagged cells to circulate and localize within the bone marrow.
  • Step 5: Administration of Additional Isotopes - In some cases, other isotopes may also be injected intravenously to enhance the imaging results and provide additional information about the bone marrow.
  • Step 6: Imaging Procedure - After a specified period, imaging is performed using Single Photon Emission Computed Tomography (SPECT) and/or Positron Emission Tomography (PET) scanning. These imaging modalities capture detailed images of the bone marrow, allowing for assessment of its functional activity.
  • Step 7: Interpretation of Images - The physician interprets the images obtained from the ECT, SPECT, CT, or PET scans. This interpretation is vital for diagnosing conditions, assessing treatment responses, and planning further management.
  • Step 8: Reporting Findings - Finally, the physician compiles a written report detailing the findings from the imaging study, which is then used for clinical decision-making.

3. Post-Procedure

Post-procedure care for patients undergoing bone marrow imaging typically involves monitoring for any immediate reactions to the radionuclide injection. Patients may be advised to drink plenty of fluids to help flush the radionuclide from their system. There are generally no significant restrictions following the procedure, and patients can resume normal activities unless otherwise directed by their healthcare provider. Follow-up appointments may be scheduled to discuss the results of the imaging and any further diagnostic or therapeutic steps that may be necessary based on the findings.

Short Descr BONE MARROW IMAGING LTD
Medium Descr BONE MARROW IMAGING LIMITED AREA
Long Descr Bone marrow imaging; limited area
Status Code Active Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 1 - Diagnostic Tests for Radiology Services
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Not Discounted when Multiple
ASC Payment Indicator Radiology service paid separately when provided integral to a surgical procedure on ASC list; payment based on OPPS relative payment weight.
Type of Service (TOS) 4 - Diagnostic Radiology
Berenson-Eggers TOS (BETOS) I1E - Standard imaging - nuclear medicine
MUE 1
CCS Clinical Classification 207 - Radioisotope bone scan
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
GC This service has been performed in part by a resident under the direction of a teaching physician
MG The order for this service does not have applicable appropriate use criteria in the qualified clinical decision support mechanism consulted by the ordering professional
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
CR Catastrophe/disaster related
GW Service not related to the hospice patient's terminal condition
MF The order for this service does not adhere to the appropriate use criteria in the clinical decision support mechanism consulted by the ordering professional
MH Unknown if ordering professional consulted a clinical decision support mechanism for this service, related information was not provided to the furnishing professional or provider
TC Technical component; under certain circumstances, a charge may be made for the technical component alone; under those circumstances the technical component charge is identified by adding modifier 'tc' to the usual procedure number; technical component charges are institutional charges and not billed separately by physicians; however, portable x-ray suppliers only bill for technical component and should utilize modifier tc; the charge data from portable x-ray suppliers will then be used to build customary and prevailing profiles
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
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2011-01-01 Changed Short description changed.
Pre-1990 Added Code added.
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