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Official Description

Lymphatics and lymph nodes imaging

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 78195 refers to the imaging of the lymphatic system and lymph nodes, a critical procedure used to evaluate the structure and function of lymphatic vessels. This imaging technique is essential for identifying metastatic disease, which is the spread of cancer from one part of the body to another, and for quantifying lymphedema, a condition characterized by swelling due to lymph fluid accumulation. The lymphatic system is a complex network of vessels that transport lymph fluid, which contains lymphocytes—white blood cells that play a vital role in the immune response—as well as various substances such as viruses, bacteria, pollen, toxins, and malignant cells. These harmful agents are filtered and trapped by lymph nodes, which act as a defense mechanism for the body. One of the most common methods for performing this imaging is lymphoscintigraphy, which utilizes a radiolabeled isotope tracer, specifically 18-F-FDG (Fluorodeoxyglucose). This procedure may be conducted with or without the addition of Single Photon Emission Computed Tomography (SPECT), a technique that enhances the imaging quality by providing three-dimensional representations of the lymphatic structures. In cases of malignant disease, lymphoscintigraphy is particularly useful for identifying sentinel lymph nodes, which are the first nodes to receive lymphatic drainage from a tumor. This information is crucial for planning biopsies, surgical staging, and developing treatment plans. During the imaging process, a gamma camera is employed to detect the radioactive energy emitted from the patient's body, converting this energy into visual images. For patients diagnosed with melanoma, the procedure typically involves administering 2-5 injections of the radiolabeled tracer into the interstitial tissue surrounding the tumor site. The patient is then positioned on an X-ray table, and imaging is conducted over a period of 1-2 hours. In breast cancer patients, the tracer is injected at multiple sites within the breast, chest, and axilla, with imaging taking place over a duration of 30 minutes to more than 2 hours. When evaluating lymphedema, the tracer is injected between the first and second digits of the hand or foot, and the affected extremity is scanned for a period ranging from 30 minutes to over 3 hours. In cases of unilateral lymphedema, both the affected and unaffected limbs are scanned to provide a comprehensive assessment. Additionally, patients may be instructed to perform mild exercises during the study to enhance the flow and uptake of the radiolabeled isotope. Following the imaging, the physician interprets the scintigraphic and/or SPECT images and generates a written report detailing the findings.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The imaging of the lymphatic system and lymph nodes using CPT® Code 78195 is indicated for several specific clinical scenarios, including:

  • Metastatic Disease Evaluation - This procedure is performed to identify the presence of metastatic disease, particularly in patients with known malignancies.
  • Lymphedema Assessment - It is utilized to quantify lymphedema, helping to determine the extent of lymph fluid accumulation in affected limbs.
  • Sentinel Lymph Node Identification - The imaging is crucial for locating sentinel lymph nodes in patients with malignant tumors, which aids in surgical planning and staging.
  • Biopsy Planning - The procedure assists in planning biopsies by identifying the most relevant lymph nodes for sampling.
  • Treatment Planning - It provides essential information for creating comprehensive treatment plans for patients with lymphatic or oncological conditions.
  • Blockage Identification - The imaging can help identify areas of blockage in the lymphatic system, particularly in cases of lymphedema.

2. Procedure

The procedure for lymphatics and lymph nodes imaging using CPT® Code 78195 involves several detailed steps, which are outlined as follows:

  • Tracer Injection - The first step involves the administration of a radiolabeled isotope tracer, typically 18-F-FDG, into specific areas depending on the clinical indication. For melanoma patients, 2-5 injections are given in the interstitial tissue surrounding the tumor site. In breast cancer cases, multiple injections are made in the breast, chest, and axilla. For lymphedema assessment, the tracer is injected between the first and second digits of the hand or foot.
  • Patient Positioning - After the tracer is injected, the patient is positioned on an X-ray table to facilitate imaging. Proper positioning is crucial to ensure that the gamma camera can effectively capture the emitted radioactive energy from the body.
  • Imaging Process - The imaging is conducted using a gamma camera, which detects the radioactive energy emitted from the patient's body. This process converts the energy into images that represent the lymphatic system and lymph nodes. The duration of imaging varies: for melanoma, it typically lasts 1-2 hours; for breast cancer, it can range from 30 minutes to over 2 hours; and for lymphedema, it may take 30 minutes to over 3 hours.
  • Exercise Facilitation - During some studies, the patient may be asked to perform mild exercises to enhance the flow and uptake of the radiolabeled isotope, which can improve the quality of the images obtained.
  • Image Interpretation - Once imaging is complete, the physician interprets the scintigraphic and/or SPECT images. This interpretation is critical for diagnosing conditions related to the lymphatic system and for planning further treatment.

3. Post-Procedure

After the imaging procedure using CPT® Code 78195, patients may be monitored briefly to ensure there are no immediate adverse reactions to the tracer. The physician will provide a detailed interpretation of the images obtained, which will be documented in a written report. This report will outline the findings and any relevant observations regarding the lymphatic system and lymph nodes. Patients may be advised on any necessary follow-up appointments or additional tests based on the results of the imaging. It is important for patients to understand that the imaging process is non-invasive and typically does not require extensive recovery time, allowing them to resume normal activities shortly after the procedure.

Short Descr LYMPH SYSTEM IMAGING
Medium Descr LYMPHATICS & LYMPH NODES IMAGING
Long Descr Lymphatics and lymph nodes imaging
Status Code Active Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 1 - Diagnostic Tests for Radiology Services
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Not Discounted when Multiple
ASC Payment Indicator Radiology service paid separately when provided integral to a surgical procedure on ASC list; payment based on OPPS relative payment weight.
Type of Service (TOS) 4 - Diagnostic Radiology
Berenson-Eggers TOS (BETOS) I1E - Standard imaging - nuclear medicine
MUE 1
CCS Clinical Classification 209 - Radioisotope scan and function studies
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
GC This service has been performed in part by a resident under the direction of a teaching physician
MG The order for this service does not have applicable appropriate use criteria in the qualified clinical decision support mechanism consulted by the ordering professional
MH Unknown if ordering professional consulted a clinical decision support mechanism for this service, related information was not provided to the furnishing professional or provider
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
LT Left side (used to identify procedures performed on the left side of the body)
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
QQ Ordering professional consulted a qualified clinical decision support mechanism for this service and the related data was provided to the furnishing professional
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
MD Ordering professional is not required to consult a clinical decision support mechanism due to the significant hardship exception of extreme and uncontrollable circumstances
MF The order for this service does not adhere to the appropriate use criteria in the clinical decision support mechanism consulted by the ordering professional
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
RT Right side (used to identify procedures performed on the right side of the body)
50 Bilateral procedure: unless otherwise identified in the listings, bilateral procedures that are performed at the same session, should be identified by adding modifier 50 to the appropriate 5 digit code. note: this modifier should not be appended to designated "add-on" codes (see appendix d).
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
CR Catastrophe/disaster related
GA Waiver of liability statement issued as required by payer policy, individual case
GW Service not related to the hospice patient's terminal condition
MA Ordering professional is not required to consult a clinical decision support mechanism due to service being rendered to a patient with a suspected or confirmed emergency medical condition
MB Ordering professional is not required to consult a clinical decision support mechanism due to the significant hardship exception of insufficient internet access
MC Ordering professional is not required to consult a clinical decision support mechanism due to the significant hardship exception of electronic health record or clinical decision support mechanism vendor issues
ME The order for this service adheres to appropriate use criteria in the clinical decision support mechanism consulted by the ordering professional
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
TC Technical component; under certain circumstances, a charge may be made for the technical component alone; under those circumstances the technical component charge is identified by adding modifier 'tc' to the usual procedure number; technical component charges are institutional charges and not billed separately by physicians; however, portable x-ray suppliers only bill for technical component and should utilize modifier tc; the charge data from portable x-ray suppliers will then be used to build customary and prevailing profiles
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XP Separate practitioner, a service that is distinct because it was performed by a different practitioner
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
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2002-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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