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Official Description

Bone and/or joint imaging; whole body

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 78306 refers to whole body imaging of bones and/or joints using scintigraphy, a specialized imaging technique that employs a radiolabeled isotope tracer. This method is particularly useful for patients experiencing unexplained skeletal pain that may indicate conditions such as bone loss, infection, inflammation, or injury, especially when traditional radiographic methods, like planar X-rays, have not yielded a definitive diagnosis. The process begins with the establishment of an intravenous line, through which the radiolabeled isotope tracer is injected into the patient's circulatory system. In cases where inflammation is suspected, a blood sample may be collected and processed to isolate white blood cells (WBCs). These WBCs are then tagged with a radioactive calcium compound and reintroduced into the patient’s body. Following a designated waiting period, the patient is positioned on an imaging table, and a gamma camera is used to scan the body. The imaging can be limited to specific areas of concern or, in the case of a comprehensive assessment, encompass the entire body. The emitted radioactive energy is captured and transformed into detailed images, which the physician subsequently interprets to generate a written report outlining the findings of the bone and/or joint imaging study.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure is indicated for patients who present with unexplained skeletal pain that may suggest various underlying conditions. The specific indications for performing whole body bone and/or joint imaging using scintigraphy include:

  • Unexplained Skeletal Pain - Patients experiencing pain in the bones or joints without a clear diagnosis from traditional imaging methods.
  • Bone Loss - Assessment of potential osteoporosis or other conditions leading to decreased bone density.
  • Infection - Evaluation for possible osteomyelitis or other infections affecting the skeletal system.
  • Inflammation - Investigation of inflammatory conditions such as arthritis or other inflammatory diseases.
  • Injury - Diagnosis of fractures or other injuries that may not be visible on standard X-rays.

2. Procedure

The procedure for whole body bone and/or joint imaging using scintigraphy involves several key steps, which are detailed as follows:

  • Step 1: Establishing an Intravenous Line - The first step in the procedure is to establish an intravenous (IV) line in the patient. This allows for the safe and effective administration of the radiolabeled isotope tracer directly into the circulatory system.
  • Step 2: Injection of Radiolabeled Isotope Tracer - Once the IV line is in place, the radiolabeled isotope tracer is injected. This tracer is crucial for highlighting areas of interest within the bones and joints during imaging.
  • Step 3: Blood Sample Collection (if inflammation is suspected) - If there is a suspicion of inflammation, a blood sample is drawn from the patient. This sample is then centrifuged to separate the white blood cells (WBCs) from the rest of the blood components.
  • Step 4: Tagging White Blood Cells - The separated WBCs are tagged with a radioactive calcium compound. This step enhances the imaging of inflammatory processes within the body.
  • Step 5: Re-injection of Tagged WBCs - The tagged WBCs are then injected back into the patient, allowing them to circulate and accumulate in areas of inflammation.
  • Step 6: Imaging Procedure - After a prescribed waiting period to allow for the tracer to distribute throughout the body, the patient is positioned on the imaging table. A gamma camera is then used to scan the entire body or specific areas of interest, depending on the clinical indication.
  • Step 7: Image Capture and Interpretation - The gamma camera captures the radioactive energy emitted from the tracer, converting it into images. These images are then interpreted by the physician, who prepares a written report detailing the findings of the imaging study.

3. Post-Procedure

After the completion of the whole body bone and/or joint imaging procedure, patients may be monitored briefly to ensure there are no immediate adverse reactions to the tracer. There are typically no specific post-procedure care requirements, and patients can usually resume normal activities immediately. However, they may be advised to drink plenty of fluids to help flush the radioactive material from their system. The physician will provide the patient with the results of the imaging study in a written report, which will include any findings that may require further evaluation or treatment.

Short Descr BONE IMAGING WHOLE BODY
Medium Descr BONE &/JOINT IMAGING WHOLE BODY
Long Descr Bone and/or joint imaging; whole body
Status Code Active Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 1 - Diagnostic Tests for Radiology Services
Multiple Procedures (51) 4 - Special payment adjustment rules on the technical component (TC) of multiple diagnostic imaging procedures apply...
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 88 -
APC Status Indicator Procedure or Service, Not Discounted when Multiple
ASC Payment Indicator Radiology service paid separately when provided integral to a surgical procedure on ASC list; payment based on OPPS relative payment weight.
Type of Service (TOS) 4 - Diagnostic Radiology
Berenson-Eggers TOS (BETOS) I1E - Standard imaging - nuclear medicine
MUE 1
CCS Clinical Classification 207 - Radioisotope bone scan
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
GC This service has been performed in part by a resident under the direction of a teaching physician
MG The order for this service does not have applicable appropriate use criteria in the qualified clinical decision support mechanism consulted by the ordering professional
ME The order for this service adheres to appropriate use criteria in the clinical decision support mechanism consulted by the ordering professional
TC Technical component; under certain circumstances, a charge may be made for the technical component alone; under those circumstances the technical component charge is identified by adding modifier 'tc' to the usual procedure number; technical component charges are institutional charges and not billed separately by physicians; however, portable x-ray suppliers only bill for technical component and should utilize modifier tc; the charge data from portable x-ray suppliers will then be used to build customary and prevailing profiles
MH Unknown if ordering professional consulted a clinical decision support mechanism for this service, related information was not provided to the furnishing professional or provider
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
XP Separate practitioner, a service that is distinct because it was performed by a different practitioner
QQ Ordering professional consulted a qualified clinical decision support mechanism for this service and the related data was provided to the furnishing professional
MF The order for this service does not adhere to the appropriate use criteria in the clinical decision support mechanism consulted by the ordering professional
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
GA Waiver of liability statement issued as required by payer policy, individual case
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
MC Ordering professional is not required to consult a clinical decision support mechanism due to the significant hardship exception of electronic health record or clinical decision support mechanism vendor issues
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
CR Catastrophe/disaster related
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Q5 Service furnished under a reciprocal billing arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
FY X-ray taken using computed radiography technology/cassette-based imaging
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
GZ Item or service expected to be denied as not reasonable and necessary
JZ Zero drug amount discarded/not administered to any patient
KX Requirements specified in the medical policy have been met
LT Left side (used to identify procedures performed on the left side of the body)
MA Ordering professional is not required to consult a clinical decision support mechanism due to service being rendered to a patient with a suspected or confirmed emergency medical condition
MB Ordering professional is not required to consult a clinical decision support mechanism due to the significant hardship exception of insufficient internet access
PD Diagnostic or related non diagnostic item or service provided in a wholly owned or operated entity to a patient who is admitted as an inpatient within 3 days
Q0 Investigational clinical service provided in a clinical research study that is in an approved clinical research study
RT Right side (used to identify procedures performed on the right side of the body)
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
Date
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2011-01-01 Changed Short description changed.
Pre-1990 Added Code added.
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