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Official Description

Fibrin(ogen) degradation (split) products (FDP) (FSP); agglutination slide, semiquantitative

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 85362 refers to a laboratory test that measures semiquantitative fibrin(ogen) degradation (split) products, commonly known as FDP (FSP), using an agglutination slide method. Fibrin degradation products are fragments that result from the breakdown of fibrin, a protein involved in blood clotting, by the enzyme plasmin. This process occurs when a clot is dissolved, and the presence of these fragments can indicate various pathological conditions. The test is designed to detect large amounts of FDP (FSP) in the blood, although it is important to note that it does not differentiate between the breakdown of a clot (fibrinolysis) and the degradation of intact fibrinogen (fibrinogenolysis). Both serum and plasma samples can contain FDP (FSP); however, serum testing is not recommended for evaluating FDP levels or diagnosing coagulopathies, such as disseminated intravascular coagulation (DIC). Plasma testing is preferred as it provides a more accurate assessment of FDP levels. Additionally, the D-dimer test is recommended for evaluating coagulopathies. Elevated levels of FDP (FSP) can be indicative of several medical conditions, including DIC, thromboembolic events, acute myocardial infarction, preeclampsia, renal failure, sepsis or shock, post-operative status, and even strenuous physical exercise. The blood sample for this test is obtained through a venipuncture, which is a separately reportable procedure, and the analysis of the serum or plasma is conducted using a latex agglutination technique.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The test coded by CPT® 85362 is indicated for the assessment of various medical conditions where the presence of fibrin(ogen) degradation products is relevant. The following conditions may warrant the use of this test:

  • Disseminated Intravascular Coagulation (DIC) - A serious condition characterized by the widespread activation of the clotting process, leading to the formation of blood clots throughout the small blood vessels.
  • Thromboembolic Events - Situations where blood clots form in blood vessels and may travel to other parts of the body, potentially causing blockages.
  • Acute Myocardial Infarction - Commonly known as a heart attack, this condition occurs when blood flow to a part of the heart is blocked, leading to damage to the heart muscle.
  • Preeclampsia - A pregnancy complication characterized by high blood pressure and signs of damage to another organ system, often the kidneys.
  • Renal Failure - A condition in which the kidneys lose the ability to filter waste and excess fluids from the blood.
  • Sepsis/Shock - A life-threatening condition that arises when the body's response to infection causes injury to its tissues and organs.
  • Post-Operative Status - The period following surgery, during which monitoring for complications such as clot formation is critical.
  • Strenuous Exercise - Intense physical activity that can lead to temporary increases in FDP levels due to muscle and tissue breakdown.

2. Procedure

The procedure for conducting the test associated with CPT® 85362 involves several key steps to ensure accurate measurement of fibrin(ogen) degradation products. The first step is the collection of a blood sample, which is performed through a venipuncture. This procedure involves inserting a needle into a vein, typically in the arm, to draw blood into a collection tube. It is important to note that the venipuncture is a separately reportable procedure and must be documented accordingly. Once the blood sample is obtained, it is processed to separate the plasma from the cellular components. Plasma is preferred for this test as it provides a more reliable measure of FDP levels. The next step involves testing the plasma using a latex agglutination method. In this technique, latex particles coated with specific antibodies are mixed with the plasma sample. If FDP (FSP) are present in the sample, they will bind to the latex particles, causing visible agglutination. The degree of agglutination is then assessed semiquantitatively, allowing for the determination of the concentration of fibrin degradation products in the sample.

3. Post-Procedure

After the completion of the test, there are no specific post-procedure care requirements for the patient, as the venipuncture site should be monitored for any signs of bleeding or discomfort. The results of the FDP (FSP) test will be interpreted in conjunction with clinical findings and other laboratory tests to provide a comprehensive assessment of the patient's coagulation status. It is essential for healthcare providers to consider the context of elevated FDP levels, as they can indicate various underlying conditions that may require further investigation or intervention.

Short Descr FIBRIN DEGRADATION PRODUCTS
Medium Descr FIBRIN DGRADJ SPLT PRODUXS AGGLUJ SLIDE SEMIQUAN
Long Descr Fibrin(ogen) degradation (split) products (FDP) (FSP); agglutination slide, semiquantitative
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 2
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
91 Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient.
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2008-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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