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Official Description

Sedimentation rate, erythrocyte; automated

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 85652 refers to the automated measurement of the erythrocyte sedimentation rate (ESR), a laboratory test that assesses the rate at which red blood cells (erythrocytes) settle in a vertical column of anticoagulated blood over a specified period, typically one hour. This test is a non-specific indicator of inflammation in the body and is often utilized to help identify various medical conditions associated with both acute and chronic inflammatory processes. Commonly, the ESR test is performed alongside other diagnostic tests to provide a more comprehensive understanding of the underlying causes of inflammation, such as infections, cancers, and autoimmune disorders. In the automated version of the test, a blood sample is first collected and treated with an anticoagulant to prevent clotting. The sample is then aspirated and introduced into an automated system designed to measure the sedimentation rate. The automation of this process enhances efficiency and accuracy, providing a reading of the sedimentation rate after the designated time has passed. It is important to note that while the basic principle of measuring the distance that erythrocytes fall remains the same, the specific techniques and equipment used can vary among different automated systems. This automation streamlines the testing process, allowing for quicker results and reducing the potential for human error in manual measurements.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The erythrocyte sedimentation rate (ESR) test, represented by CPT® Code 85652, is indicated for various clinical scenarios where inflammation is suspected. The following conditions may warrant the performance of this test:

  • Infection The ESR test can help identify the presence of an infection in the body, as inflammation is a common response to infectious agents.
  • Cancer Elevated ESR levels may indicate the presence of malignancies, as certain cancers can provoke inflammatory responses.
  • Autoimmune Diseases Conditions such as rheumatoid arthritis and lupus, which involve chronic inflammation, can be assessed using the ESR test to monitor disease activity or response to treatment.

2. Procedure

The procedure for performing the automated erythrocyte sedimentation rate (ESR) test involves several key steps that ensure accurate measurement of the sedimentation rate. The following outlines the procedural steps:

  • Step 1: Blood Sample Collection A blood sample is obtained from the patient, typically via venipuncture. The blood is collected into a tube containing an anticoagulant to prevent clotting, which is essential for accurate measurement of the sedimentation rate.
  • Step 2: Sample Preparation Once the blood sample is collected, it is carefully mixed to ensure uniform distribution of the anticoagulant. The sample is then aspirated and prepared for the automated testing system.
  • Step 3: Automated Testing The prepared blood sample is introduced into the automated ESR system. The system is designed to measure the distance that the erythrocytes fall in a vertical column over a specified time period, typically one hour. The automation allows for precise control of the testing conditions and reduces variability in results.
  • Step 4: Result Generation After the required sedimentation time has elapsed, the automated system calculates and provides a reading of the sedimentation rate. This result is then documented for further analysis and interpretation by healthcare professionals.

3. Post-Procedure

After the automated erythrocyte sedimentation rate test is completed, the results are typically reviewed by a healthcare provider. There are no specific post-procedure care requirements for patients, as the test is non-invasive and does not involve any significant risks. However, it is important for healthcare providers to interpret the results in conjunction with other clinical findings and diagnostic tests to determine the underlying cause of any identified inflammation. Follow-up may be necessary based on the results and the clinical context, particularly if further investigation or treatment is indicated.

Short Descr RBC SED RATE AUTOMATED
Medium Descr SEDIMENTATION RATE RBC AUTOMATED
Long Descr Sedimentation rate, erythrocyte; automated
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
GA Waiver of liability statement issued as required by payer policy, individual case
Q4 Service for ordering/referring physician qualifies as a service exemption
GZ Item or service expected to be denied as not reasonable and necessary
GW Service not related to the hospice patient's terminal condition
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
PN Non-excepted service provided at an off-campus, outpatient, provider-based department of a hospital
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
91 Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient.
QJ Services/items provided to a prisoner or patient in state or local custody, however the state or local government, as applicable, meets the requirements in 42 cfr 411.4 (b)
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
SA Nurse practitioner rendering service in collaboration with a physician
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
95 Synchronous telemedicine service rendered via a real-time interactive audio and video telecommunications system: synchronous telemedicine service is defined as a real-time interaction between a physician or other qualified health care professional and a patient who is located at a distant site from the physician or other qualified health care professional. the totality of the communication of information exchanged between the physician or other qualified health care professional and the patient during the course of the synchronous telemedicine service must be of an amount and nature that would be sufficient to meet the key components and/or requirements of the same service when rendered via a face-to-face interaction. modifier 95 may only be appended to the services listed in appendix p. appendix p is the list of cpt codes for services that are typically performed face-to-face, but may be rendered via a real-time (synchronous) interactive audio and video telecommunications system.
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
AY Item or service furnished to an esrd patient that is not for the treatment of esrd
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
G4 Most recent urr reading of 70 to 74.9
GC This service has been performed in part by a resident under the direction of a teaching physician
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GX Notice of liability issued, voluntary under payer policy
KX Requirements specified in the medical policy have been met
LT Left side (used to identify procedures performed on the left side of the body)
PD Diagnostic or related non diagnostic item or service provided in a wholly owned or operated entity to a patient who is admitted as an inpatient within 3 days
PO Excepted service provided at an off-campus, outpatient, provider-based department of a hospital
Q3 Live kidney donor surgery and related services
QW Clia waived test
RT Right side (used to identify procedures performed on the right side of the body)
UH Services provided in the evening
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
Action
Notes
2011-01-01 Changed Short description changed.
1996-01-01 Added First appearance in code book in 1996.
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