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The CPT® Code 88355 refers to a specialized test known as morphometric analysis of skeletal muscle. This procedure involves a detailed examination of the morphometric characteristics of skeletal muscle tissue, which is primarily composed of striated fibers that work together to facilitate contraction. The analysis is crucial as it helps identify structural changes in muscle fibers and cells that may arise due to various factors, including developmental changes, nutritional status, lifestyle choices, and pathological conditions. These changes can be influenced by several hormones, such as testosterone, growth hormone, and insulin-like growth factor-1, as well as external factors like exercise, gravitational effects, and conditions such as denervation or muscle atrophy associated with aging, injury, or illness. Genetic factors, including mutations that lead to muscular dystrophies, and variations in fat content within the muscle tissue can also impact the characteristics of muscle fibers and cells. To perform this analysis, a sample of muscle tissue is obtained through a biopsy, which is reported separately. The collected tissue is then processed and analyzed using microscopic techniques and/or advanced automated or semi-automated software programs, such as MetaMorph, AxionVision, Lucia, or CyteSeer. The results of this analysis are compiled into a comprehensive written report that details the findings, providing valuable insights into the muscle's structural integrity and potential abnormalities.
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The morphometric analysis of skeletal muscle (CPT® Code 88355) is indicated for various clinical scenarios where understanding the structural characteristics of muscle tissue is essential. This analysis is particularly relevant in the following situations:
The procedure for morphometric analysis of skeletal muscle involves several critical steps to ensure accurate and comprehensive evaluation of the muscle tissue. The following outlines the procedural steps:
Post-procedure care following the morphometric analysis of skeletal muscle primarily involves monitoring the biopsy site for any signs of complications, such as infection or excessive bleeding. Patients may be advised on activity restrictions to allow for proper healing of the biopsy site. The results of the analysis will typically be discussed with the patient in a follow-up appointment, where the implications of the findings will be explained, and any necessary further evaluations or treatments will be considered based on the results. It is essential for healthcare providers to ensure that patients understand the significance of the findings and any subsequent steps in their care plan.
| Short Descr | M/PHMTRC ALYS SKELETAL MUSC | Medium Descr | MORPHOMETRIC ANALYSIS SKELETAL MUSCLE | Long Descr | Morphometric analysis; skeletal muscle | Status Code | Active Code | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 1 - Diagnostic Tests for Radiology Services | Multiple Procedures (51) | 0 - No payment adjustment rules for multiple procedures apply. | Bilateral Surgery (50) | 0 - 150% payment adjustment for bilateral procedures does NOT apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 0 - Payment restriction for assistants at surgery applies to this procedure... | Co-Surgeons (62) | 0 - Co-surgeons not permitted for this procedure. | Team Surgery (66) | 0 - Team surgeons not permitted for this procedure. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | APC Status Indicator | STV-Packaged Codes | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1G - Lab tests - other (Medicare fee schedule) | MUE | 1 | CCS Clinical Classification | 234 - Pathology |
| 26 | Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number. | 59 | Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25. | 76 | Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service. | GW | Service not related to the hospice patient's terminal condition |
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| 2024-01-01 | Changed | Short Description changed. |
| 2011-01-01 | Changed | Short description changed. |
| Pre-1990 | Added | Code added. |
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