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The CPT® Code 88388 refers to the macroscopic examination, dissection, and preparation of tissue specifically for non-microscopic analytical studies, such as nucleic acid-based molecular studies. This procedure involves a thorough visual examination of the tissue sample, where definitive characteristics are noted to assess the sample's quality and relevance. Following this examination, the tissue undergoes dissection, which allows for a more detailed evaluation of its structure and composition. The preparation of the tissue is a critical step, which may involve fixing the tissue using chemical agents like aldehydes or alcohols, or alternatively, freezing the tissue to preserve its integrity for further analysis. Once prepared, the tissue is embedded in a medium such as paraffin or resin, which facilitates the slicing of the tissue into thin sections. These sections are essential for conducting non-microscopic analytical studies, particularly those that focus on nucleic acids. Such molecular studies are crucial for diagnosing various conditions, including genetic disorders and malignant neoplasms, as they help identify specific genetic mutations associated with these diseases. After the completion of the analytical studies, the physician interprets the results and compiles a written report detailing the findings. It is important to note that CPT® Code 88388 is used when the tissue preparation is performed in conjunction with other procedures, such as a touch imprint, intraoperative consultation, or frozen section, and should be listed separately in addition to the code for the primary procedure.
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The procedure associated with CPT® Code 88388 is indicated for various clinical scenarios where detailed analysis of tissue samples is necessary. These indications include:
The procedure for CPT® Code 88388 involves several key steps that ensure the proper preparation of tissue for non-microscopic analytical studies. These steps include:
After the completion of the tissue preparation and analysis, the physician interprets the results obtained from the molecular studies. This interpretation is critical for diagnosing any underlying conditions and determining the appropriate course of treatment. The physician will compile a written report detailing the findings of the analysis, which may include information on genetic mutations or other significant characteristics of the tissue. It is important for healthcare providers to ensure that the results are communicated effectively to the patient and incorporated into their overall treatment plan. Additionally, proper documentation of the procedure and findings is essential for compliance and billing purposes.
Short Descr | TISS EX MOLECUL STUDY ADD-ON | Medium Descr | MACR EXM DISS&PRP NONMICR IMPRNT/CONSLT/FRZ SE | Long Descr | Macroscopic examination, dissection, and preparation of tissue for non-microscopic analytical studies (eg, nucleic acid-based molecular studies); in conjunction with a touch imprint, intraoperative consultation, or frozen section, each tissue preparation (eg, a single lymph node) (List separately in addition to code for primary procedure) | Status Code | Active Code | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 1 - Diagnostic Tests for Radiology Services | Multiple Procedures (51) | 0 - No payment adjustment rules for multiple procedures apply. | Bilateral Surgery (50) | 0 - 150% payment adjustment for bilateral procedures does NOT apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 0 - Payment restriction for assistants at surgery applies to this procedure... | Co-Surgeons (62) | 0 - Co-surgeons not permitted for this procedure. | Team Surgery (66) | 0 - Team surgeons not permitted for this procedure. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | APC Status Indicator | Items and Services Packaged into APC Rates | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | M5A - Specialist - pathology (HCPCS moved to T1G in 2003) | MUE | Not applicable/unspecified. | CCS Clinical Classification | 234 - Pathology |
26 | Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number. | XU | Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service |
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2024-12-31 | Deleted | Code Deleted. |
2013-01-01 | Changed | Medium Descriptor changed. |
2010-01-01 | Added | - |