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Official Description

Bacillus Calmette-Guerin vaccine (BCG) for tuberculosis, live, for percutaneous use

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The Bacillus Calmette-Guerin vaccine (BCG) is a live vaccine specifically designed to provide active immunity against tuberculosis, a serious infectious disease caused by the bacterium Mycobacterium tuberculosis. Unlike immune globulins, which offer short-term, passive immunity, vaccines like BCG stimulate the recipient's immune system to produce its own antibodies, leading to long-term protection. This process involves exposing the immune system to a weakened form of the pathogen, allowing the body to "remember" how to respond effectively upon future exposure to the actual disease-causing organism. The BCG vaccine is derived from a live, attenuated strain of Mycobacterium bovis, which is a type of bovine tuberculosis. This strain has been cultured in a controlled environment for an extended period, rendering it nonvirulent to humans while still capable of eliciting an immune response. In addition to its primary use in preventing tuberculosis, the BCG vaccine has also been utilized in the treatment of bladder cancer, although the exact mechanisms by which it exerts its effects in oncology remain partially understood. The CPT® Code 90585 specifically refers to the administration of the live BCG vaccine for percutaneous use, while a different code, 90586, is designated for instances where the vaccine is instilled directly into the bladder via catheter for cancer treatment. It is important to note that these codes are strictly for reporting the vaccine product itself.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The Bacillus Calmette-Guerin vaccine (BCG) is indicated for the following conditions:

  • Prevention of Tuberculosis The BCG vaccine is primarily used to immunize individuals against tuberculosis, particularly in populations at high risk for the disease.
  • Treatment of Bladder Cancer The BCG vaccine is also indicated for the treatment of superficial bladder cancer, where it is instilled directly into the bladder to stimulate an immune response against cancer cells.

2. Procedure

The procedure for administering the Bacillus Calmette-Guerin vaccine (BCG) involves several key steps:

  • Step 1: Preparation of the Vaccine The BCG vaccine is prepared from a live, attenuated strain of Mycobacterium bovis. It is essential to ensure that the vaccine is stored and handled according to the manufacturer's guidelines to maintain its efficacy.
  • Step 2: Patient Assessment Prior to administration, a thorough assessment of the patient is conducted to confirm the indication for vaccination or treatment, ensuring that the patient is suitable for receiving the BCG vaccine.
  • Step 3: Administration of the Vaccine For percutaneous use, the vaccine is injected into the appropriate site on the skin. If the vaccine is being used for bladder cancer treatment, it is instilled through a catheter directly into the bladder. The method of administration is crucial for the effectiveness of the vaccine.
  • Step 4: Monitoring After administration, the patient is monitored for any immediate adverse reactions or side effects, ensuring that any potential complications are addressed promptly.

3. Post-Procedure

Post-procedure care for patients receiving the BCG vaccine includes monitoring for any adverse reactions, which may include localized swelling, redness, or systemic symptoms such as fever. Patients should be informed about potential side effects and the importance of reporting any unusual symptoms. For those receiving the vaccine for bladder cancer, follow-up appointments are necessary to assess the treatment's effectiveness and monitor for any recurrence of cancer. Additionally, patients may be advised on hydration and other supportive measures to enhance recovery and minimize discomfort following the procedure.

Short Descr BCG VACCINE PERCUT
Medium Descr BACILLUS CALMETTE-GUERIN VACC FOR TB LIVE PERQ
Long Descr Bacillus Calmette-Guerin vaccine (BCG) for tuberculosis, live, for percutaneous use
Related Drugs BCG VACCINE
Status Code Excluded from Physician Fee Schedule by Regulation
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Items and Services Not Billable to the MAC
Type of Service (TOS) 1 - Medical Care
Berenson-Eggers TOS (BETOS) O1G - Immunizations/Vaccinations
MUE 1
CCS Clinical Classification 228 - Prophylactic vaccinations and inoculations
Date
Action
Notes
2011-01-01 Changed Short description changed.
1999-01-01 Added First appearance in code book in 1999.
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