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Official Description

Haemophilus influenzae type b vaccine (Hib), PRP-OMP conjugate, 3 dose schedule, for intramuscular use

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 90647 refers to the Haemophilus influenzae type b (Hib) vaccine, specifically the PRP-OMP conjugate formulation, which is administered via intramuscular injection. Vaccines, unlike immune globulins that offer short-term, passive immunity, are designed to provide active, long-term immunity. This is achieved by introducing altered versions of specific pathogens, such as viruses or bacteria, into the recipient's body. The immune system then responds by producing its own antibodies, which enables the body to "remember" how to combat the pathogen upon future exposure. Haemophilus influenzae type b is particularly concerning for children under the age of five, as it can lead to severe health complications, including pneumonia, significant swelling of the throat, infections in the joints and bones, and meningitis, which can result in lasting effects such as brain damage and hearing loss. The code 90647 specifically denotes the administration of the PRP-OMP conjugate Hib vaccine following a 3-dose schedule, while code 90648 is designated for the PRP-T conjugate vaccine administered in a 4-dose schedule. It is important to note that these codes are strictly for reporting the vaccine product used in immunization efforts.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The Haemophilus influenzae type b (Hib) vaccine is indicated for the prevention of serious infections caused by the Hib bacteria, particularly in children under the age of five. The following conditions and symptoms highlight the necessity of vaccination:

  • Pneumonia - A severe lung infection that can lead to difficulty breathing and requires immediate medical attention.
  • Throat Swelling - Significant inflammation in the throat that can obstruct airways and lead to respiratory distress.
  • Infection of Joints and Bones - Hib can cause osteomyelitis and septic arthritis, leading to pain and mobility issues.
  • Meningitis - An infection of the protective membranes covering the brain and spinal cord, which can result in serious complications, including brain damage and deafness.

2. Procedure

The administration of the Haemophilus influenzae type b vaccine (CPT® Code 90647) follows a structured procedure to ensure effective immunization. The steps involved in the vaccination process are as follows:

  • Step 1: Preparation - Prior to administration, the healthcare provider prepares the vaccine by checking the expiration date and ensuring that the vaccine is stored at the appropriate temperature. The vial is then gently agitated to mix the contents, ensuring a uniform solution.
  • Step 2: Patient Assessment - The healthcare provider assesses the patient’s medical history to confirm that there are no contraindications to vaccination. This includes reviewing any previous allergic reactions to vaccines or components of the Hib vaccine.
  • Step 3: Site Selection - The provider selects an appropriate intramuscular injection site, typically the anterolateral thigh for infants and the deltoid muscle for older children and adults. The site is cleaned with an antiseptic wipe to reduce the risk of infection.
  • Step 4: Administration - The vaccine is administered via intramuscular injection using a sterile syringe and needle. The provider injects the vaccine into the muscle at the selected site, ensuring that the needle is inserted at the correct angle for optimal delivery.
  • Step 5: Post-Administration Care - After the injection, the provider monitors the patient for any immediate adverse reactions, such as allergic responses. The patient or guardian is provided with information regarding potential side effects and the importance of completing the full 3-dose schedule for optimal immunity.

3. Post-Procedure

Following the administration of the Haemophilus influenzae type b vaccine, patients are typically advised to remain in the healthcare setting for a short period to monitor for any immediate adverse reactions. Common post-vaccination care includes advising the patient or guardian to apply a cool compress to the injection site to alleviate any discomfort or swelling. It is also important to inform them about potential mild side effects, such as fever, irritability, or soreness at the injection site, which usually resolve on their own. Patients should be encouraged to complete the full 3-dose schedule to ensure adequate protection against Hib infections. Follow-up appointments should be scheduled to administer subsequent doses as per the recommended immunization schedule.

Short Descr HIB PRP-OMP VACC 3 DOSE IM
Medium Descr HIB PRP-OMP VACCINE 3 DOSE SCHEDULE IM USE
Long Descr Haemophilus influenzae type b vaccine (Hib), PRP-OMP conjugate, 3 dose schedule, for intramuscular use
Status Code Excluded from Physician Fee Schedule by Regulation
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Items and Services Packaged into APC Rates
ASC Payment Indicator Packaged service/item; no separate payment made.
Type of Service (TOS) 1 - Medical Care
Berenson-Eggers TOS (BETOS) O1G - Immunizations/Vaccinations
MUE 1
CCS Clinical Classification 228 - Prophylactic vaccinations and inoculations
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
GA Waiver of liability statement issued as required by payer policy, individual case
GC This service has been performed in part by a resident under the direction of a teaching physician
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
GZ Item or service expected to be denied as not reasonable and necessary
JZ Zero drug amount discarded/not administered to any patient
SK Member of high risk population (use only with codes for immunization)
SL State supplied vaccine
UC Medicaid level of care 12, as defined by each state
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Action
Notes
2016-01-01 Changed First appearance of change in codebook.
2015-07-01 Changed Description changed.
2011-01-01 Changed Short description changed.
1999-01-01 Added First appearance in code book in 1999.
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