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Official Description

Pneumococcal conjugate vaccine, 13 valent (PCV13), for intramuscular use

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The pneumococcal conjugate vaccine, 13 valent (PCV13), is a crucial immunization designed to provide active and long-term immunity against pneumococcal diseases. Vaccines function by introducing altered versions of specific pathogens, such as viruses or bacteria, into the body. This exposure prompts the immune system to produce antibodies, which are proteins that help fight off infections. Once the immune system has been exposed to the vaccine, it retains a memory of how to produce these antibodies, enabling a quicker and more effective response if the individual encounters the actual pathogen in the future. Pneumococcal bacteria, specifically Streptococcus pneumoniae, can reside harmlessly in the nose and throat; however, they pose a significant risk when they invade other parts of the body, potentially leading to severe conditions such as pneumococcal pneumonia, bacteremia, and meningitis. Certain populations, including young children, the elderly, and individuals with compromised immune systems, are particularly vulnerable to these infections. The PCV13 vaccine is formulated using a purified component of the bacteria's cell wall, which is combined with a nontoxic variant of diphtheria known as CRM197, serving as a carrier to enhance the immune response. This specific vaccine covers 13 different serotypes of Streptococcus pneumoniae, which are responsible for a majority of pneumococcal disease cases. The vaccine is administered via an intramuscular injection, and it is important to note that there are other pneumococcal vaccines available, such as the 15 valent vaccine (PCV15), which offers broader coverage by including additional serotypes. The use of the PCV13 vaccine is essential in preventing serious pneumococcal infections and protecting at-risk populations.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The pneumococcal conjugate vaccine, 13 valent (PCV13), is indicated for the prevention of pneumococcal diseases caused by specific serotypes of Streptococcus pneumoniae. The following conditions and populations are explicitly recognized for vaccination:

  • Young Children - Infants and toddlers are at a higher risk for pneumococcal infections, making vaccination essential for their protection.
  • The Elderly - Older adults, particularly those aged 65 and older, are more susceptible to severe pneumococcal diseases and complications.
  • Immune-Suppressed Individuals - Patients with weakened immune systems, whether due to medical conditions or treatments, are at increased risk for infections and benefit from vaccination.

2. Procedure

The administration of the pneumococcal conjugate vaccine, 13 valent (PCV13), involves a series of procedural steps to ensure proper delivery and effectiveness of the vaccine:

  • Step 1: Preparation - Prior to administration, the healthcare provider must prepare the vaccine by checking the expiration date and ensuring that the vaccine is stored correctly. The vial should be gently swirled to mix the contents without shaking, which could damage the vaccine.
  • Step 2: Patient Assessment - The provider should assess the patient’s medical history, including any previous allergic reactions to vaccines, current health status, and any contraindications to vaccination.
  • Step 3: Site Selection - The vaccine is administered via intramuscular injection, typically in the deltoid muscle of the upper arm for older children and adults, or in the anterolateral thigh for infants and young children.
  • Step 4: Injection - Using a sterile syringe and needle, the provider will inject the vaccine into the selected muscle site. Proper technique should be followed to minimize discomfort and ensure the vaccine is delivered effectively.
  • Step 5: Post-Administration Care - After the injection, the provider should observe the patient for a brief period to monitor for any immediate adverse reactions. The patient should be informed about potential side effects and the importance of follow-up doses if applicable.

3. Post-Procedure

Following the administration of the pneumococcal conjugate vaccine, 13 valent (PCV13), patients may experience mild side effects, such as soreness at the injection site, low-grade fever, or irritability, particularly in young children. These effects are generally short-lived and resolve without intervention. It is important for healthcare providers to educate patients or guardians about these potential reactions and to advise them on when to seek further medical attention. Additionally, patients should be informed about the importance of completing the vaccination series, if applicable, to ensure optimal protection against pneumococcal diseases. Documentation of the vaccination should be recorded in the patient's medical record, including the date of administration, vaccine lot number, and the site of injection.

Short Descr PCV13 VACCINE IM
Medium Descr PCV13 VACCINE FOR INTRAMUSCULAR USE
Long Descr Pneumococcal conjugate vaccine, 13 valent (PCV13), for intramuscular use
Related Drugs PREVNAR 13
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Influenza, Pneumococcal Pneumonia, Hepatitis B, and Covid-19 Vaccines; Monoclonal Antibody Therapy Product
ASC Payment Indicator Influenza vaccine; pneumococcal vaccine.
Type of Service (TOS) V - Pneumococcal/Flu Vaccine
Berenson-Eggers TOS (BETOS) O1G - Immunizations/Vaccinations
MUE 1
CCS Clinical Classification 228 - Prophylactic vaccinations and inoculations
GA Waiver of liability statement issued as required by payer policy, individual case
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
CR Catastrophe/disaster related
GW Service not related to the hospice patient's terminal condition
95 Synchronous telemedicine service rendered via a real-time interactive audio and video telecommunications system: synchronous telemedicine service is defined as a real-time interaction between a physician or other qualified health care professional and a patient who is located at a distant site from the physician or other qualified health care professional. the totality of the communication of information exchanged between the physician or other qualified health care professional and the patient during the course of the synchronous telemedicine service must be of an amount and nature that would be sufficient to meet the key components and/or requirements of the same service when rendered via a face-to-face interaction. modifier 95 may only be appended to the services listed in appendix p. appendix p is the list of cpt codes for services that are typically performed face-to-face, but may be rendered via a real-time (synchronous) interactive audio and video telecommunications system.
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
GC This service has been performed in part by a resident under the direction of a teaching physician
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GX Notice of liability issued, voluntary under payer policy
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
GZ Item or service expected to be denied as not reasonable and necessary
JG Drug or biological acquired with 340b drug pricing program discount, reported for informational purposes
JZ Zero drug amount discarded/not administered to any patient
LT Left side (used to identify procedures performed on the left side of the body)
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
RT Right side (used to identify procedures performed on the right side of the body)
SA Nurse practitioner rendering service in collaboration with a physician
SL State supplied vaccine
TB Drug or biological acquired with 340b drug pricing program discount, reported for informational purposes
U1 Medicaid level of care 1, as defined by each state
U6 Medicaid level of care 6, as defined by each state
X1 Continuous/broad services: for reporting services by clinicians, who provide the principal care for a patient, with no planned endpoint of the relationship; services in this category represent comprehensive care, dealing with the entire scope of patient problems, either directly or in a care coordination role; reporting clinician service examples include, but are not limited to: primary care, and clinicians providing comprehensive care to patients in addition to specialty care
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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Action
Notes
2016-01-01 Changed First appearance of change in codebook.
2015-07-01 Changed Description Changed
2011-01-01 Changed FDA Approval Pending status changed. Short description changed.
2010-01-01 Added First appearance in code book in 2010.
2009-10-01 Added -
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