© Copyright 2025 American Medical Association. All rights reserved.
The CPT® Code 91318 refers to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, specifically designed to combat coronavirus disease (COVID-19). This vaccine utilizes a formulation of messenger RNA (mRNA) encapsulated in lipid nanoparticles (LNP), which is a method that allows the mRNA to be effectively delivered into human cells. The vaccine contains a dosage of 3 mcg in a 0.3 mL volume and is specifically formulated with tris-sucrose to enhance stability and maintain the appropriate pH for storage at refrigerator temperatures. The mRNA included in this vaccine corresponds to the spike protein of the virus, which is a critical component that the immune system recognizes as foreign. Upon administration, the body’s cells utilize the mRNA to produce copies of the spike protein, prompting an immune response that generates antibodies. These antibodies are essential for recognizing and neutralizing the virus if the individual is exposed post-vaccination. This particular code is designated for the supply of the Pfizer pediatric vaccine, intended for children aged 6 months through 4 years, and it is important to note that the administration of the vaccine is reported separately from the supply code itself.
© Copyright 2025 Coding Ahead. All rights reserved.
The CPT® Code 91318 is indicated for the vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease (COVID-19). The vaccine is specifically designed for use in pediatric patients aged 6 months through 4 years. It is intended to provide protection against the potentially severe and life-threatening effects of COVID-19, particularly in young children who may be at risk for serious illness from the virus.
The administration of the vaccine involves several key procedural steps to ensure safety and efficacy. First, the vaccine must be prepared by diluting the Pfizer pediatric vaccine with normal saline to achieve the correct dosage of 3 mcg in a 0.3 mL volume. This preparation is crucial for ensuring that the vaccine is safe and effective for the target age group. Next, the healthcare provider will select an appropriate site for intramuscular injection, typically in the thigh for infants and young children. The injection site should be cleaned with an antiseptic to minimize the risk of infection. Once the site is prepared, the vaccine is administered intramuscularly, allowing the lipid nanoparticles to facilitate the uptake of mRNA by the cells. After the injection, the healthcare provider may observe the patient for a short period to monitor for any immediate adverse reactions. It is important to document the administration details, including the date, time, and site of injection, as well as any reactions observed during the monitoring period.
After the administration of the vaccine, it is essential to monitor the patient for any immediate side effects or adverse reactions, which may include mild symptoms such as soreness at the injection site, fever, or fatigue. These reactions are typically short-lived and resolve on their own. Parents or guardians should be informed about potential side effects and advised on when to seek medical attention. Additionally, it is important to schedule any follow-up doses if required, as per the vaccination schedule recommended for the pediatric population. Documentation of the vaccination, including the lot number and expiration date of the vaccine, should be recorded in the patient's medical record to ensure proper tracking and compliance with vaccination protocols.
Short Descr | SARSCOV2 VAC 3MCG TRS-SUC IM | Medium Descr | SARSCOV2 VACC 3MCG/0.3ML TRIS-SUCROSE IM USE | Long Descr | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) vaccine, mRNA-LNP, spike protein, 3 mcg/0.3 mL dosage, tris-sucrose formulation, for intramuscular use | Related Drugs | Pfizer-BioNTech Covid-19 Vaccine | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | APC Status Indicator | Influenza, Pneumococcal Pneumonia, Hepatitis B, and Covid-19 Vaccines; Monoclonal Antibody Therapy Product | Berenson-Eggers TOS (BETOS) | none | MUE | 1 |
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Notes
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2025-01-01 | Added | First appearance of code and guideline in codebook |
2023-09-11 | Added | FDA approval received |
2023-09-11 | Note | AMA Guideline changed. 90480 received FDA approval |
2023-09-08 | Note | Technical correction. |
2023-08-14 | Added | Code added, effective upon receiving Emergency Use Authorization or approval from the Food and Drug Administration |
2023-08-14 | Note | AMA guideline code 90480 published to AMA website. Effective upon receiving emergency Use Authorization or approval from the FDA. |
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