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Official Description

Thrombolysis, coronary; by intracoronary infusion, including selective coronary angiography

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

Coronary thrombolysis is a medical procedure aimed at dissolving blood clots that obstruct coronary arteries, which can lead to serious cardiovascular events such as heart attacks. The procedure described by CPT® Code 92975 involves the direct administration of a thrombolytic agent through an intracoronary infusion. This method is typically performed when a patient presents with acute coronary syndrome, characterized by symptoms such as chest pain, shortness of breath, or other signs of myocardial ischemia. The procedure begins with the insertion of a catheter from a major access vessel, commonly the femoral or brachial artery, which is then navigated to the site of the thrombus within the coronary artery. Once the catheter is positioned correctly, a thrombolytic agent—such as streptokinase, alteplase, or reteplase—is infused directly into the artery to facilitate the breakdown of the clot. Following the infusion, contrast material is injected to conduct a selective coronary angiography, allowing the physician to visualize the artery and confirm that the thrombus has been effectively dissolved and that blood flow is restored. This procedure is critical in managing acute coronary events and improving patient outcomes by restoring perfusion to the heart muscle.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

Coronary thrombolysis by intracoronary infusion (CPT® Code 92975) is indicated for patients experiencing acute coronary syndrome, which may manifest as:

  • Acute Myocardial Infarction - A condition where blood flow to a part of the heart is blocked, leading to damage of the heart muscle.
  • Unstable Angina - A type of chest pain that occurs unpredictably and may signal an impending heart attack.
  • Coronary Thrombosis - The presence of a blood clot within a coronary artery that impedes blood flow.

2. Procedure

The procedure for coronary thrombolysis via intracoronary infusion involves several critical steps:

  • Step 1: Access Site Preparation - The procedure begins with the selection of an appropriate access site, typically the femoral or brachial artery. The area is cleaned and sterilized to minimize the risk of infection.
  • Step 2: Catheter Insertion - A catheter is inserted into the chosen artery. This catheter is carefully advanced through the vascular system to reach the coronary arteries where the thrombus is located.
  • Step 3: Thrombolytic Agent Administration - Once the catheter is positioned at the site of the thrombus, a thrombolytic agent is injected directly into the affected coronary artery. This agent works to dissolve the blood clot, restoring blood flow.
  • Step 4: Selective Coronary Angiography - After the thrombolytic agent has been administered, contrast material is injected through the catheter. This allows for selective coronary angiography, which is performed to visualize the coronary arteries and confirm that the thrombus has been successfully dissolved and that the artery is patent.

3. Post-Procedure

Following the intracoronary thrombolysis procedure, patients are typically monitored for any complications, such as bleeding at the access site or signs of re-occlusion of the artery. Continuous cardiac monitoring is essential to assess the patient's heart function and detect any arrhythmias. Patients may also require additional medications, such as antiplatelet agents, to prevent further clot formation. The expected recovery period can vary based on the individual patient's condition and response to the procedure, but close follow-up is necessary to ensure optimal outcomes and manage any potential complications.

Short Descr DISSOLVE CLOT HEART VESSEL
Medium Descr THROMBOLYSIS INTRACORONARY NFS SLCTV ANGRPH
Long Descr Thrombolysis, coronary; by intracoronary infusion, including selective coronary angiography
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Inpatient Procedures, not paid under OPPS
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P2F - Major procedure, cardiovascular-Other
MUE 1
CCS Clinical Classification 46 - Coronary thrombolysis

This is a primary code that can be used with these additional add-on codes.

92972 Add On Code Resequenced Code MPFS Status: Active Code APC N Percutaneous transluminal coronary lithotripsy (List separately in addition to code for primary procedure)
92973 Addon Code Resequenced Code MPFS Status: Active Code APC N CPT Assistant Article Illustration for Code Percutaneous transluminal coronary thrombectomy mechanical (List separately in addition to code for primary procedure)
92978 Addon Code CPT Resequenced MPFS Status: Carrier Priced APC N ASC N1 CPT Assistant Article Illustration for Code Endoluminal imaging of coronary vessel or graft using intravascular ultrasound (IVUS) or optical coherence tomography (OCT) during diagnostic evaluation and/or therapeutic intervention including imaging supervision, interpretation and report; initial vessel (List separately in addition to code for primary procedure)
93571 Addon Code MPFS Status: Carrier Priced APC N ASC N1 CPT Assistant Article Intravascular Doppler velocity and/or pressure derived coronary flow reserve measurement (coronary vessel or graft) during coronary angiography including pharmacologically induced stress; initial vessel (List separately in addition to code for primary procedure)
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
LD Left anterior descending coronary artery
RC Right coronary artery
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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Notes
2017-01-01 Changed Moderate (Conscious) Sedation flag removed. See new Moderate Sedation category.
2011-01-01 Changed Short description changed.
Pre-1990 Added Code added.
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