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Official Description

Chemotherapy administration; intravenous, push technique, each additional substance/drug (List separately in addition to code for primary procedure)

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 96411 refers to the administration of chemotherapy through an intravenous push (IVP) technique, specifically for each additional substance or drug administered. This procedure is crucial in the treatment of malignant neoplasms, where multiple chemotherapy agents may be required to effectively combat cancer. The intravenous push technique involves the direct injection of a chemotherapy drug into the patient's bloodstream via an existing intravenous line or an intermittent infusion set, commonly known as a saline lock. This method allows for rapid delivery of the medication, typically completed in a short duration, usually less than 15 minutes. It is important to note that this code is used in conjunction with the primary procedure code, which is 96409, designated for the initial chemotherapy substance or drug administered. Therefore, CPT® Code 96411 serves as an add-on code, indicating that additional chemotherapy substances or drugs are being administered sequentially through the same venous access site, ensuring accurate coding and billing for the services provided.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The administration of chemotherapy via intravenous push technique, as described by CPT® Code 96411, is indicated for patients undergoing treatment for malignant neoplasms. This procedure is typically performed when multiple chemotherapy agents are required to enhance the effectiveness of cancer treatment. The use of this code is appropriate when additional chemotherapy substances or drugs are administered sequentially to a patient who is already receiving treatment through an established intravenous access.

  • Malignant Neoplasm Treatment The procedure is indicated for patients diagnosed with various types of cancer, where chemotherapy is a part of the treatment regimen.

2. Procedure

The procedure for administering chemotherapy using CPT® Code 96411 involves several key steps that ensure the safe and effective delivery of the drug. First, the healthcare provider prepares the chemotherapy substance or drug to be administered. This preparation may include verifying the medication, checking for any potential interactions, and ensuring that the dosage is appropriate for the patient's treatment plan. Once the medication is ready, the provider will access the patient's existing intravenous line or intermittent infusion set. This is crucial as it allows for the direct delivery of the chemotherapy agent into the bloodstream.

  • Step 1: Preparation of Chemotherapy Drug The healthcare provider prepares the chemotherapy substance, ensuring proper dosage and checking for any contraindications.
  • Step 2: Accessing the Venous Line The provider accesses the existing intravenous line or saline lock to facilitate the administration of the drug.
  • Step 3: Administration of the Drug The chemotherapy substance is injected directly into the vein using a syringe, typically over a period of less than 15 minutes, ensuring that the patient is monitored for any immediate reactions.

3. Post-Procedure

After the administration of chemotherapy using CPT® Code 96411, the patient is typically monitored for any adverse reactions or side effects that may occur as a result of the drug. This monitoring is essential to ensure patient safety and to address any complications promptly. The healthcare provider may also provide post-procedure instructions regarding hydration, potential side effects, and when to seek medical attention. Additionally, documentation of the procedure, including the substances administered and the patient's response, is crucial for accurate medical records and billing purposes.

Short Descr CHEMO IV PUSH ADDL DRUG
Medium Descr CHEMOTX ADMN IV PUSH TQ EA SBST/DRUG
Long Descr Chemotherapy administration; intravenous, push technique, each additional substance/drug (List separately in addition to code for primary procedure)
Status Code Active Code
Global Days ZZZ - Code Related to Another Service
PC/TC Indicator (26, TC) 5 - Incident To Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Not Discounted when Multiple
Type of Service (TOS) 1 - Medical Care
Berenson-Eggers TOS (BETOS) P7B - Oncology - other
MUE 3
CCS Clinical Classification 224 - Cancer chemotherapy

This is an add-on code that must be used in conjunction with one of these primary codes.

96409 MPFS Status: Active Code APC S Physician Quality Reporting PUB 100 CPT Assistant Article Chemotherapy administration; intravenous, push technique, single or initial substance/drug
96413 MPFS Status: Active Code APC S Physician Quality Reporting PUB 100 CPT Assistant Article Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug
0663T Add-on Code MPFS Status: Carrier Priced APC N Scalp cooling, mechanical; placement of device, monitoring, and removal of device (List separately in addition to code for primary procedure)
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
X2 Continuous/focused services: for reporting services by clinicians whose expertise is needed for the ongoing management of a chronic disease or a condition that needs to be managed and followed with no planned endpoint to the relationship; reporting clinician service examples include but are not limited to: a rheumatologist taking care of the patient's rheumatoid arthritis longitudinally but not providing general primary care services
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
CR Catastrophe/disaster related
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
25 Significant, separately identifiable evaluation and management service by the same physician or other qualified health care professional on the same day of the procedure or other service: it may be necessary to indicate that on the day a procedure or service identified by a cpt code was performed, the patient's condition required a significant, separately identifiable e/m service above and beyond the other service provided or beyond the usual preoperative and postoperative care associated with the procedure that was performed. a significant, separately identifiable e/m service is defined or substantiated by documentation that satisfies the relevant criteria for the respective e/m service to be reported (see evaluation and management services guidelines for instructions on determining level of e/m service). the e/m service may be prompted by the symptom or condition for which the procedure and/or service was provided. as such, different diagnoses are not required for reporting of the e/m services on the same date. this circumstance may be reported by adding modifier 25 to the appropriate level of e/m service. note: this modifier is not used to report an e/m service that resulted in a decision to perform surgery. see modifier 57 for significant, separately identifiable non-e/m services, see modifier 59.
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
GA Waiver of liability statement issued as required by payer policy, individual case
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
JW Drug amount discarded/not administered to any patient
JZ Zero drug amount discarded/not administered to any patient
KX Requirements specified in the medical policy have been met
PD Diagnostic or related non diagnostic item or service provided in a wholly owned or operated entity to a patient who is admitted as an inpatient within 3 days
Q0 Investigational clinical service provided in a clinical research study that is in an approved clinical research study
Q5 Service furnished under a reciprocal billing arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
SA Nurse practitioner rendering service in collaboration with a physician
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
Date
Action
Notes
2011-01-01 Changed Short description changed.
2006-01-01 Added First appearance in code book in 2006.
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