CPT® Code 96422

1. Indications

The intra-arterial chemotherapy administration using CPT® Code 96422 is indicated for the treatment of malignant neoplasms. This procedure is particularly beneficial in cases where localized treatment is necessary to target tumors directly, thereby maximizing the therapeutic effect of the chemotherapy while reducing exposure to the rest of the body. The following conditions may warrant the use of this procedure:

• Malignant Neoplasms - The primary indication for intra-arterial chemotherapy is the presence of cancerous tumors that require localized treatment.

2. Procedure

The procedure for intra-arterial chemotherapy administration involves several critical steps to ensure effective delivery of the chemotherapy agent. Each step is essential for the successful execution of the treatment:

• Step 1: Patient Preparation - The patient is prepared for the procedure, which may include obtaining informed consent, reviewing medical history, and performing necessary pre-procedural assessments to ensure the patient is a suitable candidate for intra-arterial chemotherapy.
• Step 2: Catheterization - An arterial catheterization is performed under radiologic supervision. This step involves the insertion of a catheter into the appropriate artery that supplies blood to the tumor site. The use of imaging techniques ensures accurate placement of the catheter for optimal drug delivery.
• Step 3: Administration of Chemotherapy - Once the catheter is in place, the chemotherapy substance or drug is infused directly into the artery. This infusion is conducted over a period of up to one hour, allowing for concentrated delivery of the medication to the tumor while minimizing systemic exposure.

3. Post-Procedure

After the intra-arterial chemotherapy administration, the patient may require monitoring for any immediate adverse reactions to the chemotherapy agent. Post-procedure care typically includes assessing the catheter site for any signs of complications, such as bleeding or infection. Patients may also be advised on potential side effects of the chemotherapy and the importance of follow-up appointments to evaluate the treatment's effectiveness and manage any ongoing symptoms. It is crucial for healthcare providers to provide clear instructions regarding recovery and any necessary lifestyle modifications following the procedure.