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Official Description

Debridement of premalignant hyperkeratotic lesion(s) (ie, targeted curettage, abrasion) followed with photodynamic therapy by external application of light to destroy premalignant lesions of the skin and adjacent mucosa with application and illumination/activation of photosensitizing drug(s) provided by a physician or other qualified health care professional, per day

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

Photodynamic therapy (PDT) is a medical procedure that utilizes photosensitive chemicals, also known as photoreactive agents, in conjunction with light exposure to effectively target and destroy premalignant lesions on the skin and adjacent mucosal areas. This therapy is particularly relevant for conditions characterized by hyperkeratosis, where there is an abnormal thickening of the outer layer of the skin. The process begins with the debridement of these hyperkeratotic lesions, which can be achieved through techniques such as targeted curettage or abrasion. This initial step is crucial as it prepares the lesions for the subsequent application of photoreactive chemicals. Once the lesions are adequately prepared, the chemicals are applied topically to the affected areas. Following this application, the area is illuminated with light of a specific wavelength, which activates the photosensitizing agents. This activation leads to a photochemical reaction that results in the destruction of the premalignant lesions. The procedure is performed by a physician or other qualified healthcare professional and is billed once per day, reflecting the comprehensive nature of the treatment provided during that time frame.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure is indicated for the treatment of premalignant hyperkeratotic lesions, which may include conditions such as actinic keratosis. These lesions are characterized by thickened, scaly patches on the skin that have the potential to progress to skin cancer if left untreated. The use of photodynamic therapy is particularly beneficial for patients with multiple lesions in a specific anatomic area, such as the face or scalp, where traditional surgical methods may be less desirable.

  • Premalignant Hyperkeratotic Lesions These lesions are abnormal growths on the skin that have the potential to develop into cancer if not addressed.
  • Actinic Keratosis A common type of premalignant lesion caused by prolonged sun exposure, presenting as rough, scaly patches on sun-exposed skin.

2. Procedure

The procedure involves several key steps to ensure effective treatment of the premalignant lesions. First, the physician or qualified healthcare professional performs nonsurgical debridement of the hyperkeratotic lesions. This is accomplished through targeted curettage, where a curette is used to scrape away the lesions, or through abrasion, which involves the mechanical removal of the outer layer of skin. This debridement is essential as it removes any overlying crust or scale, allowing for better penetration of the photoreactive chemicals that will be applied next.

  • Step 1: Nonsurgical Debridement The healthcare provider carefully removes the hyperkeratotic lesions using targeted curettage or abrasion techniques to prepare the skin for treatment.
  • Step 2: Application of Photoreactive Chemicals After debridement, photosensitizing agents are applied topically to the lesions. These chemicals are designed to react to specific wavelengths of light.
  • Step 3: Illumination/Activation The treated area is then exposed to light of the appropriate wavelength, which activates the photoreactive chemicals. This activation triggers a photochemical reaction that leads to the destruction of the premalignant lesions.

3. Post-Procedure

After the procedure, patients may experience some localized redness, swelling, or discomfort in the treated area, which is a normal response to the photodynamic therapy. It is important for patients to follow any post-procedure care instructions provided by their healthcare professional, which may include avoiding sun exposure and using specific topical treatments to aid in healing. The expected recovery time can vary depending on the extent of the lesions treated and the individual patient's response to the therapy. Follow-up appointments may be necessary to assess the effectiveness of the treatment and to monitor for any potential recurrence of lesions.

Short Descr DBRDMT PRMLG LES W/PDT
Medium Descr DEBRIDEMENT PRMLG HYPERKERATOTIC LES W/PDT
Long Descr Debridement of premalignant hyperkeratotic lesion(s) (ie, targeted curettage, abrasion) followed with photodynamic therapy by external application of light to destroy premalignant lesions of the skin and adjacent mucosa with application and illumination/activation of photosensitizing drug(s) provided by a physician or other qualified health care professional, per day
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator STV-Packaged Codes
Berenson-Eggers TOS (BETOS) none
MUE 1
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
SA Nurse practitioner rendering service in collaboration with a physician
GC This service has been performed in part by a resident under the direction of a teaching physician
KX Requirements specified in the medical policy have been met
24 Unrelated evaluation and management service by the same physician or other qualified health care professional during a postoperative period: the physician or other qualified health care professional may need to indicate that an evaluation and management service was performed during a postoperative period for a reason(s) unrelated to the original procedure. this circumstance may be reported by adding modifier 24 to the appropriate level of e/m service.
25 Significant, separately identifiable evaluation and management service by the same physician or other qualified health care professional on the same day of the procedure or other service: it may be necessary to indicate that on the day a procedure or service identified by a cpt code was performed, the patient's condition required a significant, separately identifiable e/m service above and beyond the other service provided or beyond the usual preoperative and postoperative care associated with the procedure that was performed. a significant, separately identifiable e/m service is defined or substantiated by documentation that satisfies the relevant criteria for the respective e/m service to be reported (see evaluation and management services guidelines for instructions on determining level of e/m service). the e/m service may be prompted by the symptom or condition for which the procedure and/or service was provided. as such, different diagnoses are not required for reporting of the e/m services on the same date. this circumstance may be reported by adding modifier 25 to the appropriate level of e/m service. note: this modifier is not used to report an e/m service that resulted in a decision to perform surgery. see modifier 57 for significant, separately identifiable non-e/m services, see modifier 59.
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
97 Rehabilitative services: when a service or procedure that may be either habilitative or rehabilitative in nature is provided for rehabilitative purposes, the physician or other qualified health care professional may add modifier 97 to the service or procedure code to indicate that the service or procedure provided was a rehabilitative service. rehabilitative services help an individual keep, get back, or improve skills and functioning for daily living that have been lost or impaired because the individual was sick, hurt, or disabled.
AG Primary physician
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
GA Waiver of liability statement issued as required by payer policy, individual case
GW Service not related to the hospice patient's terminal condition
JZ Zero drug amount discarded/not administered to any patient
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
T5 Right foot, great toe
UD Medicaid level of care 13, as defined by each state
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
Date
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2018-01-01 Added Code Added.
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