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Official Description

Digitization of glass microscope slides for special stain, including interpretation and report, group II, all other (eg, iron, trichrome), except stain for microorganisms, stains for enzyme constituents, or immunocytochemistry and immunohistochemistry (List separately in addition to code for primary procedure)

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 0757T refers to the process of digitizing glass microscope slides that have undergone special staining, which includes the interpretation and reporting of the findings. This procedure is categorized under group II, encompassing all special stains except those specifically used for microorganisms, enzyme constituents, or immunocytochemistry and immunohistochemistry. The digitization process involves scanning glass slides into a digital format, allowing the captured images to be stored either on a local computer server or within a cloud-based archive. This digital transformation facilitates further examination by remote pathologists or through the use of computer algorithms, which can assist in providing a pathologic diagnosis. The slides that are digitized typically originate from surgical biopsy tissues, cytology cell samples, blood, or other bodily substances. Special stains utilized in this process may include trichrome staining, which helps differentiate collagen from smooth muscle in tumors; iron staining, which identifies non-heme iron deposits in tissues such as the liver and bone marrow; and Congo red staining, which is used to detect amyloids in tissue samples. It is important to report code 0757T in conjunction with a group II special stain for all other types, excluding those for microorganisms, enzyme constituents, or immunohistochemistry, when the digitization of slides is performed simultaneously to acquire a pathological diagnosis along with the interpretation and report, distinguishing it from traditional direct visualization through a microscope.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 0757T is indicated for the digitization of glass microscope slides that have been prepared with special stains. This process is particularly useful in the following scenarios:

  • Pathological Diagnosis The digitization of slides allows for remote examination and interpretation by pathologists, facilitating timely and accurate diagnoses.
  • Special Staining Analysis The procedure is indicated when special stains, such as trichrome or iron stains, are utilized to enhance the visualization of specific tissue components.
  • Research and Education Digitized slides can be used for educational purposes and research, allowing for easier sharing and collaboration among medical professionals.

2. Procedure

The procedure for digitizing glass microscope slides involves several key steps, which are detailed as follows:

  • Preparation of Slides Initially, glass microscope slides are prepared from various samples, including surgical biopsy tissues, cytology cell samples, blood, or other bodily substances. Special stains are applied to these slides to enhance the visualization of specific cellular or tissue components.
  • Scanning of Slides Once the slides are prepared and stained, they are placed into a digital slide imaging system. The system scans the slides, capturing high-resolution images that are then converted into a digital format. This process ensures that all details of the stained slides are accurately represented in the digital images.
  • Storage of Digital Images The scanned images are stored on a local computer server or within a cloud-based archive. This digital storage allows for easy access and management of the images, facilitating further analysis and interpretation.
  • Interpretation and Reporting After digitization, the images can be reviewed by pathologists, who may utilize computer algorithms to assist in the diagnostic process. A comprehensive report is generated based on the interpretation of the digital images, providing essential information for clinical decision-making.

3. Post-Procedure

Post-procedure care following the digitization of glass microscope slides primarily involves the management of the digital images and the generated reports. The pathologist may need to follow up on any findings that require further investigation or additional testing. The digital images can be easily shared with other healthcare professionals for collaborative review or educational purposes. Additionally, the storage of these images in a digital format allows for long-term archiving and retrieval, ensuring that the information remains accessible for future reference or research. There are no specific recovery considerations for the procedure itself, as it is a technical process that does not involve patient intervention.

Short Descr DGTZ GLS MCRSCP SL SPC GRPII
Medium Descr DGTZ GLASS MCRSCP SLD SPEC STAIN GRP II ALL OTH
Long Descr Digitization of glass microscope slides for special stain, including interpretation and report, group II, all other (eg, iron, trichrome), except stain for microorganisms, stains for enzyme constituents, or immunocytochemistry and immunohistochemistry (List separately in addition to code for primary procedure)
Status Code Carriers Price the Code
Global Days ZZZ - Code Related to Another Service
PC/TC Indicator (26, TC) 3 - Technical Component Only Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Items and Services Packaged into APC Rates
Berenson-Eggers TOS (BETOS) none
MUE 8

This is an add-on code that must be used in conjunction with one of these primary codes.

88313 MPFS Status: Active Code APC Q1 PUB 100 CPT Assistant Article Special stain including interpretation and report; Group II, all other (eg, iron, trichrome), except stain for microorganisms, stains for enzyme constituents, or immunocytochemistry and immunohistochemistry
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
GW Service not related to the hospice patient's terminal condition
Date
Action
Notes
2023-01-01 Added Code added.
Code
Description
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