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Official Description

Digitization of glass microscope slides for special stain, including interpretation and report, group III, for enzyme constituents (List separately in addition to code for primary procedure)

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 0759T refers to the process of digitizing glass microscope slides specifically for special stains, which includes the interpretation and reporting of the findings. This procedure falls under group III and is particularly focused on enzyme constituents. The digitization process involves scanning glass microscope slides into a digital format, allowing the captured images to be stored either on a local computer server or within a cloud-based archive. This transition to digital imaging facilitates further examination by remote pathologists or through the use of computer algorithms, which can assist in providing a pathologic diagnosis. The information obtained from these digital slides can be managed and interpreted within an increasingly image-based environment, enhancing the diagnostic capabilities of healthcare professionals. The procedure begins with the preparation of special stain slides, which are then scanned into a digital slide imaging system. Special stains for enzyme constituents, such as nitro blue tetrazolium, are utilized to stain for succinate dehydrogenase (SDH) in mitochondrial membranes, thereby demonstrating a muscle cell's aerobic ability. Another example includes the use of NADH-TR to reveal myofiber injury patterns associated with congenital myopathies and certain muscular dystrophies. It is important to report code 0759T in conjunction with the special stain for enzyme constituents when the digitization of slides occurs simultaneously for the purpose of acquiring a pathological diagnosis, with the interpretation and report being distinctly separate from direct visualization through a microscope.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 0759T is indicated for the following conditions:

  • Special Stains for Enzyme Constituents This procedure is performed when there is a need to analyze specific enzyme constituents within tissue samples, which can provide critical information regarding various pathologies.
  • Pathologic Diagnosis The digitization of slides is indicated when a pathologic diagnosis is required, allowing for enhanced examination and interpretation of the stained slides.
  • Remote Pathology Review This procedure is beneficial when remote pathologists need to review the digitized slides, facilitating consultations and second opinions without the need for physical slide transport.

2. Procedure

The procedure for CPT® Code 0759T involves several key steps that ensure the effective digitization and interpretation of glass microscope slides:

  • Preparation of Special Stain Slides Initially, the glass microscope slides are prepared with special stains that target specific enzyme constituents. This preparation is crucial as it enhances the visibility of the enzymes within the tissue samples, allowing for accurate analysis.
  • Scanning of Slides Once the slides are prepared, they are scanned into a digital slide imaging system. This scanning process converts the physical slides into high-resolution digital images, which can be stored on a local server or in a cloud-based archive for easy access and management.
  • Interpretation and Reporting After digitization, the images are interpreted by pathologists or analyzed using computer algorithms. The findings are documented in a report, which provides a detailed account of the observations made during the examination of the digital slides. This report is essential for clinical decision-making and further patient management.

3. Post-Procedure

Post-procedure care for CPT® Code 0759T includes ensuring that the digital images are securely stored and easily accessible for future reference. The interpretation report should be reviewed by the relevant healthcare professionals to integrate the findings into the patient's overall clinical picture. Additionally, any follow-up actions or further diagnostic tests should be planned based on the results obtained from the digitized slides. It is also important to maintain the integrity and confidentiality of the digital data in compliance with healthcare regulations.

Short Descr DGTZ GLS MCRSCP SL SP GRPIII
Medium Descr DGTZ GLAS MCRSCP SLD SPEC STN GRP III NZM CONST
Long Descr Digitization of glass microscope slides for special stain, including interpretation and report, group III, for enzyme constituents (List separately in addition to code for primary procedure)
Status Code Carriers Price the Code
Global Days ZZZ - Code Related to Another Service
PC/TC Indicator (26, TC) 3 - Technical Component Only Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Items and Services Packaged into APC Rates
Berenson-Eggers TOS (BETOS) none
MUE 1

This is an add-on code that must be used in conjunction with one of these primary codes.

88319 MPFS Status: Active Code APC Q2 PUB 100 Special stain including interpretation and report; Group III, for enzyme constituents
Date
Action
Notes
2023-01-01 Added Code added.
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