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Official Description

Digitization of glass microscope slides for immunofluorescence, per specimen; each additional single antibody stain procedure (List separately in addition to code for primary procedure)

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 0846T refers to the process of digitizing glass microscope slides specifically for immunofluorescence procedures. This involves converting physical glass slides into a digital format, allowing for the images to be stored either on a local computer server or in a cloud-based archive. The digitization process is significant as it facilitates further examination of the slides, which can be conducted by remote pathologists or through the use of computer algorithms that assist in providing pathologic diagnoses. This method of analysis is distinct from traditional direct visualization through a microscope, as it enables a more versatile approach to pathology. The information obtained from the digitized slides can be managed and interpreted within an increasingly image-based environment, enhancing the diagnostic capabilities of healthcare professionals. The procedure is particularly relevant when an immunofluorescence antibody stain is performed, such as on a skin biopsy specimen, where the digitization of the microscope slides occurs concurrently. For billing purposes, it is important to report CPT® Code 0845T for the first initial single antibody stain and CPT® Code 0846T for each additional single antibody stain digitization performed.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 0846T is indicated for the digitization of glass microscope slides in the context of immunofluorescence staining. This procedure is typically performed when there is a need to analyze tissue specimens, such as skin biopsies, using immunofluorescence techniques. The indications for this procedure may include, but are not limited to, the following:

  • Skin Biopsy Analysis The digitization is performed to facilitate the examination of skin biopsy specimens that require immunofluorescence staining for diagnostic purposes.
  • Remote Pathology Consultation The procedure allows for remote pathologists to review and interpret the digitized images, enhancing diagnostic accuracy and collaboration.
  • Utilization of Computer Algorithms The digitized slides can be analyzed using advanced computer algorithms to assist in the pathologic diagnosis, providing a modern approach to pathology.

2. Procedure

The procedure for CPT® Code 0846T involves several key steps that ensure the effective digitization of glass microscope slides for immunofluorescence. Each step is crucial for achieving high-quality digital images that can be utilized for further analysis.

  • Step 1: Preparation of Specimen The process begins with the preparation of the tissue specimen, such as a skin biopsy, which is subjected to an immunofluorescence antibody stain procedure. This staining is essential for highlighting specific antigens within the tissue.
  • Step 2: Slide Creation Once the specimen is stained, it is mounted onto a glass microscope slide. This slide serves as the medium through which the immunofluorescence can be visualized and subsequently digitized.
  • Step 3: Digitization Process The glass microscope slide is then scanned using a specialized digital imaging system. This system captures high-resolution images of the stained slide, converting them into a digital format that can be stored and analyzed.
  • Step 4: Data Storage The digitized images are stored on a local computer server or within a cloud-based archive. This storage solution allows for easy access and management of the images for future reference and analysis.
  • Step 5: Reporting For billing purposes, it is important to report CPT® Code 0845T for the first initial single antibody stain and CPT® Code 0846T for each additional single antibody stain digitization performed, ensuring accurate coding and reimbursement.

3. Post-Procedure

After the digitization procedure is completed, the healthcare provider may need to ensure that the digital images are properly stored and accessible for future analysis. The expected recovery from the procedure itself is minimal, as it primarily involves the technical process of scanning slides rather than any invasive intervention. Additionally, pathologists or other healthcare professionals may review the digitized images remotely, allowing for timely diagnoses and consultations. It is also important to maintain the integrity and security of the digital data, ensuring compliance with relevant regulations regarding patient information and data management.

Short Descr DGTZ GLS MCRSCP IMFLUOR EA
Medium Descr DGTZ GLS MCRSCP SLD IMFLUOR EACH ADDL 1 ANTB STN
Long Descr Digitization of glass microscope slides for immunofluorescence, per specimen; each additional single antibody stain procedure (List separately in addition to code for primary procedure)
Status Code Carriers Price the Code
Global Days ZZZ - Code Related to Another Service
PC/TC Indicator (26, TC) 3 - Technical Component Only Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Items and Services Packaged into APC Rates
Berenson-Eggers TOS (BETOS) none
MUE Not applicable/unspecified.

This is an add-on code that must be used in conjunction with one of these primary codes.

88350 Addon Code Resequenced Code MPFS Status: Active Code APC N Immunofluorescence, per specimen; each additional single antibody stain procedure (List separately in addition to code for primary procedure)
88350 Addon Code Resequenced Code MPFS Status: Active Code APC N Immunofluorescence, per specimen; each additional single antibody stain procedure (List separately in addition to code for primary procedure)
Date
Action
Notes
2024-01-01 Added Code Added.
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