CPT® Code 0855T

Add-On Code

1. Indications

The digitization of glass microscope slides for bone marrow smear interpretation is indicated in various clinical scenarios where detailed examination of bone marrow samples is necessary. The following conditions may warrant this procedure:

• Bone Marrow Disorders The procedure is often performed for patients suspected of having hematological disorders, such as leukemia, lymphoma, or myelodysplastic syndromes, where a thorough evaluation of bone marrow is critical for diagnosis.
• Diagnostic Confirmation It is indicated for confirming diagnoses made through initial examinations, allowing for a more comprehensive analysis of cellular morphology and pathology.
• Monitoring Treatment Response The digitization process can be utilized to monitor the effectiveness of ongoing treatments in patients with known bone marrow conditions, providing a means to assess changes in cellular composition over time.

2. Procedure

The procedure for digitizing glass microscope slides involves several key steps that ensure the accurate capture and storage of bone marrow samples. Each step is crucial for maintaining the integrity of the samples and the quality of the digital images.

• Preparation of the Slide Initially, a glass slide is prepared by placing a thin smear of the bone marrow aspirate, core, or clot onto the surface of the slide. This smear must be spread evenly to allow for optimal visualization of the cellular components.
• Fixation and Staining After the smear is prepared, it is fixed in place using a special stain. This staining process is essential as it enhances the contrast of the cellular structures, making them more distinguishable during the digitization process.
• Scanning the Slide Once the slide is prepared and stained, it is then scanned using a digital microscope or slide scanner. This equipment captures high-resolution images of the slide, converting the physical sample into a digital format.
• Storage of Digital Images The resulting digital images are stored either on a local computer server or within a cloud-based archive. This storage solution allows for easy access and retrieval by pathologists for further examination and analysis.
• Remote Access and Analysis Finally, the digitized images can be accessed remotely by pathologists, enabling them to conduct detailed examinations and interpretations. Additionally, computer algorithms may be employed to assist in diagnosing conditions based on the digital images.

3. Post-Procedure

Post-procedure care for the digitization of glass microscope slides primarily involves ensuring that the digital images are securely stored and easily accessible for future reference. There are no specific recovery protocols associated with this procedure, as it is a technical process rather than an invasive medical intervention. However, it is essential to maintain the integrity of the digital files and ensure that they are backed up appropriately to prevent data loss. Pathologists may review the digitized images at their convenience, and any findings or diagnoses should be documented in the patient's medical record for continuity of care.