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Official Description

Incisional biopsy of skin (eg, wedge) (including simple closure, when performed); single lesion

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

An incisional biopsy of the skin, as described by CPT® Code 11106, is a surgical procedure that involves the removal of a small wedge-shaped section of tissue from a single lesion on the skin. This procedure is primarily performed to obtain a sample of the lesion for pathological examination, which helps in identifying the cellular composition and type of cells present within the lesion. Incisional biopsies are particularly indicated when a lesion is too large to be completely excised or when it is necessary to determine the most appropriate treatment options while ensuring that the cosmetic outcome is acceptable for the patient. The procedure typically involves the use of local anesthesia to numb the area, allowing for a more comfortable experience for the patient. The incision is made carefully to minimize trauma to the surrounding tissue, and the excised specimen is then sent for further analysis to assist in diagnosis and treatment planning.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The incisional biopsy of the skin is indicated for the following conditions:

  • Single Lesion This procedure is performed when there is a single lesion that requires further evaluation to determine its nature and appropriate treatment.
  • Large Lesion An incisional biopsy is particularly useful for larger lesions that cannot be completely excised in one procedure, allowing for a sample to be taken for diagnostic purposes.
  • Diagnostic Uncertainty When there is uncertainty regarding the diagnosis of a skin lesion, an incisional biopsy can provide critical information about the cellular makeup of the lesion.

2. Procedure

The procedure for an incisional biopsy of the skin involves several key steps:

  • Preparation The area surrounding the lesion is first marked to outline the section of skin that will be biopsied. Local anesthetic is then infiltrated into the marked area to ensure the patient experiences minimal discomfort during the procedure.
  • Incision A scalpel blade is used to make an incision along the marked lines, cutting through the skin and down to the subcutaneous tissue. This incision creates a wedge-shaped island of skin and tissue that includes the lesion.
  • Specimen Removal The island of tissue is grasped in the center with forceps and carefully excised down to the fat layer just below the dermis. The excised specimen is then placed in a container for pathological examination.
  • Wound Assessment After the specimen is removed, the wound is checked for any bleeding. The lateral edges of the skin are grasped with forceps or skin hooks to observe for approximation, ensuring that the edges can be brought together effectively.
  • Tissue Undermining If necessary, the tissue may be undermined using a scalpel or scissors to relax the skin edges, facilitating better approximation during closure.
  • Suturing Absorbable sutures may be placed in the subcutaneous tissue to reduce tension and maintain wound integrity. Finally, the skin is closed using either sutures or staples, completing the procedure.

3. Post-Procedure

Post-procedure care for an incisional biopsy includes monitoring the wound for signs of infection, ensuring that the sutures or staples remain intact, and managing any discomfort with appropriate pain relief measures. Patients are typically advised to keep the area clean and dry, and to follow any specific instructions provided by the healthcare provider regarding wound care. Follow-up appointments may be scheduled to assess healing and to discuss the results of the pathological examination of the biopsy specimen.

Short Descr INCAL BX SKN SINGLE LES
Medium Descr INCISIONAL BIOPSY SKIN SINGLE LESION
Long Descr Incisional biopsy of skin (eg, wedge) (including simple closure, when performed); single lesion
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Multiple Reduction Applies
ASC Payment Indicator Office-based surgical procedure added to ASC list in CY 2008 or later with MPFS nonfacility PE RVUs; payment based on MPFS nonfacility PE RVUs.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) none
MUE 1

This is a primary code that can be used with these additional add-on codes.

11103 Add-on Code MPFS Status: Active Code APC N ASC N1 Tangential biopsy of skin (eg, shave, scoop, saucerize, curette); each separate/additional lesion (List separately in addition to code for primary procedure)
11105 Add-on Code MPFS Status: Active Code APC N ASC N1 Punch biopsy of skin (including simple closure, when performed); each separate/additional lesion (List separately in addition to code for primary procedure)
11107 Add-on Code MPFS Status: Active Code APC N ASC N1 Incisional biopsy of skin (eg, wedge) (including simple closure, when performed); each separate/additional lesion (List separately in addition to code for primary procedure)
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
RT Right side (used to identify procedures performed on the right side of the body)
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
AG Primary physician
E2 Lower left, eyelid
E3 Upper right, eyelid
E1 Upper left, eyelid
GC This service has been performed in part by a resident under the direction of a teaching physician
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
95 Synchronous telemedicine service rendered via a real-time interactive audio and video telecommunications system: synchronous telemedicine service is defined as a real-time interaction between a physician or other qualified health care professional and a patient who is located at a distant site from the physician or other qualified health care professional. the totality of the communication of information exchanged between the physician or other qualified health care professional and the patient during the course of the synchronous telemedicine service must be of an amount and nature that would be sufficient to meet the key components and/or requirements of the same service when rendered via a face-to-face interaction. modifier 95 may only be appended to the services listed in appendix p. appendix p is the list of cpt codes for services that are typically performed face-to-face, but may be rendered via a real-time (synchronous) interactive audio and video telecommunications system.
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
CG Policy criteria applied
CR Catastrophe/disaster related
E4 Lower right, eyelid
F1 Left hand, second digit
F2 Left hand, third digit
F3 Left hand, fourth digit
F4 Left hand, fifth digit
F5 Right hand, thumb
F7 Right hand, third digit
F8 Right hand, fourth digit
FA Left hand, thumb
GA Waiver of liability statement issued as required by payer policy, individual case
GE This service has been performed by a resident without the presence of a teaching physician under the primary care exception
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
GZ Item or service expected to be denied as not reasonable and necessary
LT Left side (used to identify procedures performed on the left side of the body)
PO Excepted service provided at an off-campus, outpatient, provider-based department of a hospital
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
Q9 One class b and two class c findings
QW Clia waived test
SG Ambulatory surgical center (asc) facility service
T1 Left foot, second digit
T2 Left foot, third digit
T3 Left foot, fourth digit
T4 Left foot, fifth digit
T5 Right foot, great toe
T6 Right foot, second digit
T7 Right foot, third digit
T9 Right foot, fifth digit
TA Left foot, great toe
UA Medicaid level of care 10, as defined by each state
X2 Continuous/focused services: for reporting services by clinicians whose expertise is needed for the ongoing management of a chronic disease or a condition that needs to be managed and followed with no planned endpoint to the relationship; reporting clinician service examples include but are not limited to: a rheumatologist taking care of the patient's rheumatoid arthritis longitudinally but not providing general primary care services
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
Date
Action
Notes
2019-01-01 Added Added
Code
Description
Code
Description
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