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Official Description

Sigmoidoscopy, flexible; diagnostic, including collection of specimen(s) by brushing or washing, when performed (separate procedure)

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

A flexible sigmoidoscopy is a diagnostic procedure that involves the use of a flexible endoscope to examine the lower part of the colon, specifically the rectum and sigmoid colon. This procedure is performed to identify any abnormalities within the mucosal surfaces of the colon, such as ulcerations, varices, bleeding sites, lesions, strictures, or other pathological conditions. During the procedure, the sigmoidoscope is inserted into the anus and carefully advanced through the rectum into the sigmoid colon. Air insufflation is utilized to expand the colon and separate the mucosal folds, allowing for a clearer view of the internal structures. The physician inspects the mucosal surfaces for any irregularities and notes any findings. In addition to visual inspection, the procedure may include the collection of specimens for further analysis. This can be done through brushing or washing techniques. A brush can be introduced through the endoscope to obtain cytology samples, which are then sent for laboratory analysis. Alternatively, sterile water may be introduced to wash the mucosal lining, and the fluid is subsequently aspirated to collect cell samples. If any suspicious areas are identified during the examination, the procedure may be followed by biopsy, which involves taking tissue samples for further evaluation. The flexible sigmoidoscopy is classified as a separate procedure when performed solely for diagnostic purposes, as indicated by the CPT® code 45330.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

Flexible sigmoidoscopy is indicated for various clinical scenarios where examination of the lower colon is necessary. The following conditions may warrant the performance of this procedure:

  • Screening for Colorectal Cancer Patients at average risk for colorectal cancer may undergo flexible sigmoidoscopy as a screening tool to detect early signs of cancer or precancerous lesions.
  • Investigation of Gastrointestinal Symptoms Patients presenting with symptoms such as rectal bleeding, unexplained abdominal pain, or changes in bowel habits may require this procedure to identify potential underlying causes.
  • Monitoring of Inflammatory Bowel Disease Individuals with a history of inflammatory bowel disease, such as ulcerative colitis or Crohn's disease, may undergo flexible sigmoidoscopy to monitor disease progression or response to treatment.
  • Evaluation of Polyps Patients with known polyps or a family history of colorectal polyps may be evaluated using flexible sigmoidoscopy to assess the need for further intervention.

2. Procedure

The flexible sigmoidoscopy procedure involves several key steps to ensure a thorough examination of the lower colon. The following outlines the procedural steps:

  • Preparation of the Patient Prior to the procedure, the patient is typically instructed to follow a specific bowel preparation regimen to ensure the colon is clear of stool. This may involve dietary restrictions and the use of laxatives.
  • Insertion of the Sigmoidoscope The patient is positioned comfortably, usually lying on their left side. The flexible sigmoidoscope, a long, thin tube equipped with a light and camera, is gently inserted into the anus and advanced through the rectum into the sigmoid colon.
  • Insufflation of Air Air is insufflated through the sigmoidoscope to expand the colon, allowing for better visualization of the mucosal surfaces. This step is crucial for separating the mucosal folds and facilitating a comprehensive examination.
  • Inspection of Mucosal Surfaces The physician carefully inspects the mucosal surfaces of the colon for any abnormalities, such as lesions, ulcerations, or signs of bleeding. Any findings are documented for further analysis.
  • Collection of Specimens If necessary, a brush may be introduced through the endoscope to collect cytology samples. Alternatively, sterile water can be used to wash the mucosal lining, and the aspirated fluid can be analyzed for cell samples.
  • Biopsy (if indicated) If any suspicious areas are identified, biopsy forceps can be introduced through the endoscope to obtain tissue samples. The forceps are opened to capture the tissue, then closed and withdrawn, allowing for the collection of one or more biopsy specimens.
  • Withdrawal of the Sigmoidoscope After the examination and any necessary specimen collection, the sigmoidoscope is carefully withdrawn, and the physician may perform a final inspection of the mucosal surfaces as the instrument is removed.

3. Post-Procedure

After the flexible sigmoidoscopy, patients are typically monitored for a short period to ensure there are no immediate complications. It is common for patients to experience mild cramping or bloating due to the air insufflation, which usually resolves quickly. Patients may be advised to rest for the remainder of the day and can typically resume normal activities the following day. If biopsies were taken, results may take several days to return, and patients should be informed about when to expect follow-up communication regarding their results. Additionally, any specific post-procedure instructions, such as dietary recommendations or signs of complications to watch for, should be provided to the patient before discharge.

Short Descr DIAGNOSTIC SIGMOIDOSCOPY
Medium Descr SIGMOIDOSCOPY FLX DX W/COLLJ SPEC BR/WA IF PFRMD
Long Descr Sigmoidoscopy, flexible; diagnostic, including collection of specimen(s) by brushing or washing, when performed (separate procedure)
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Procedure or Service, Multiple Reduction Applies
ASC Payment Indicator Office-based surgical procedure added to ASC list in CY 2008 or later with MPFS nonfacility PE RVUs; payment based on MPFS nonfacility PE RVUs.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P8C - Endoscopy - sigmoidoscopy
MUE 1
CCS Clinical Classification 77 - Proctoscopy and anorectal biopsy
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
GC This service has been performed in part by a resident under the direction of a teaching physician
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
PT Colorectal cancer screening test; converted to diagnostic test or other procedure
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
74 Discontinued out-patient hospital/ambulatory surgery center (asc) procedure after administration of anesthesia: due to extenuating circumstances or those that threaten the well being of the patient, the physician may terminate a surgical or diagnostic procedure after the administration of anesthesia (local, regional block(s), general) or after the procedure was started (incision made, intubation started, scope inserted, etc). under these circumstances, the procedure started but terminated can be reported by its usual procedure number and the addition of modifier 74. note: the elective cancellation of a service prior to the administration of anesthesia and/or surgical preparation of the patient should not be reported. for physician reporting of a discontinued procedure, see modifier 53.
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
SG Ambulatory surgical center (asc) facility service
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
CR Catastrophe/disaster related
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
25 Significant, separately identifiable evaluation and management service by the same physician or other qualified health care professional on the same day of the procedure or other service: it may be necessary to indicate that on the day a procedure or service identified by a cpt code was performed, the patient's condition required a significant, separately identifiable e/m service above and beyond the other service provided or beyond the usual preoperative and postoperative care associated with the procedure that was performed. a significant, separately identifiable e/m service is defined or substantiated by documentation that satisfies the relevant criteria for the respective e/m service to be reported (see evaluation and management services guidelines for instructions on determining level of e/m service). the e/m service may be prompted by the symptom or condition for which the procedure and/or service was provided. as such, different diagnoses are not required for reporting of the e/m services on the same date. this circumstance may be reported by adding modifier 25 to the appropriate level of e/m service. note: this modifier is not used to report an e/m service that resulted in a decision to perform surgery. see modifier 57 for significant, separately identifiable non-e/m services, see modifier 59.
62 Two surgeons: when 2 surgeons work together as primary surgeons performing distinct part(s) of a procedure, each surgeon should report his/her distinct operative work by adding modifier 62 to the procedure code and any associated add-on code(s) for that procedure as long as both surgeons continue to work together as primary surgeons. each surgeon should report the co-surgery once using the same procedure code. if additional procedure(s) (including add-on procedure(s) are performed during the same surgical session, separate code(s) may also be reported with modifier 62 added. note: if a co-surgeon acts as an assistant in the performance of additional procedure(s), other than those reported with the modifier 62, during the same surgical session, those services may be reported using separate procedure code(s) with modifier 80 or modifier 82 added, as appropriate.
73 Discontinued out-patient hospital/ambulatory surgery center (asc) procedure prior to the administration of anesthesia: due to extenuating circumstances or those that threaten the well being of the patient, the physician may cancel a surgical or diagnostic procedure subsequent to the patient's surgical preparation (including sedation when provided, and being taken to the room where the procedure is to be performed), but prior to the administration of anesthesia (local, regional block(s) or general). under these circumstances, the intended service that is prepared for but cancelled can be reported by its usual procedure number and the addition of modifier 73. note: the elective cancellation of a service prior to the administration of anesthesia and/or surgical preparation of the patient should not be reported. for physician reporting of a discontinued procedure, see modifier 53.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
77 Repeat procedure by another physician or other qualified health care professional: it may be necessary to indicate that a basic procedure or service was repeated by another physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 77 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
95 Synchronous telemedicine service rendered via a real-time interactive audio and video telecommunications system: synchronous telemedicine service is defined as a real-time interaction between a physician or other qualified health care professional and a patient who is located at a distant site from the physician or other qualified health care professional. the totality of the communication of information exchanged between the physician or other qualified health care professional and the patient during the course of the synchronous telemedicine service must be of an amount and nature that would be sufficient to meet the key components and/or requirements of the same service when rendered via a face-to-face interaction. modifier 95 may only be appended to the services listed in appendix p. appendix p is the list of cpt codes for services that are typically performed face-to-face, but may be rendered via a real-time (synchronous) interactive audio and video telecommunications system.
AF Specialty physician
AG Primary physician
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
AR Physician provider services in a physician scarcity area
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CC Procedure code change (use 'cc' when the procedure code submitted was changed either for administrative reasons or because an incorrect code was filed)
ET Emergency services
GA Waiver of liability statement issued as required by payer policy, individual case
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
GZ Item or service expected to be denied as not reasonable and necessary
KX Requirements specified in the medical policy have been met
PO Excepted service provided at an off-campus, outpatient, provider-based department of a hospital
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
UA Medicaid level of care 10, as defined by each state
X4 Episodic/focused services: for reporting services by clinicians who provide focused care on particular types of treatment limited to a defined period and circumstance; the patient has a problem, acute or chronic, that will be treated with surgery, radiation, or some other type of generally time-limited intervention; reporting clinician service examples include but are not limited to, the orthopedic surgeon performing a knee replacement and seeing the patient through the postoperative period
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XP Separate practitioner, a service that is distinct because it was performed by a different practitioner
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