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Official Description

Excision of penile plaque (Peyronie disease);

© Copyright 2025 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 54110 involves the excision of penile plaque associated with Peyronie's disease. Peyronie's disease is a medical condition characterized by the formation of a hard, fibrous layer of scar tissue, known as plaque, which develops beneath the skin in the spongy erectile tissue of the penis. This plaque can lead to a curvature of the penis during an erection, causing discomfort and potential difficulties with sexual function. The excision procedure aims to remove this plaque to alleviate the curvature and restore normal function. During the procedure, the overlying tissue is carefully incised to expose the plaque. The surgeon may then either expand the plaque by making several linear cuts or excise it entirely. Depending on the extent of the excision, the areas may be covered with a graft, which can be made from skin, vein, or synthetic material. It is important to note that the specific CPT® codes used will depend on whether the procedure is performed with or without graft repair, with additional codes available for grafts of varying sizes.

© Copyright 2025 Coding Ahead. All rights reserved.

1. Indications

The excision of penile plaque associated with Peyronie's disease is indicated for patients who experience significant curvature of the penis due to the presence of fibrous plaque. This curvature can lead to discomfort, pain during erections, and difficulties with sexual intercourse. The procedure is typically considered when conservative treatments have failed to provide relief or when the curvature is severe enough to warrant surgical intervention.

  • Peyronie's Disease The primary indication for this procedure is the presence of Peyronie's disease, which manifests as a hard, fibrous plaque causing penile curvature.
  • Significant Curvature The procedure is indicated when the curvature of the penis is severe enough to cause pain or interfere with sexual function.
  • Failure of Conservative Treatments Surgical excision is considered when non-surgical treatments have not alleviated symptoms or improved the condition.

2. Procedure

The procedure for excising penile plaque associated with Peyronie's disease involves several key steps that ensure the effective removal of the plaque while minimizing damage to surrounding tissues.

  • Step 1: Anesthesia Administration The procedure typically begins with the administration of local anesthesia to ensure the patient is comfortable and pain-free during the surgery. In some cases, general anesthesia may be used depending on the patient's condition and the extent of the procedure.
  • Step 2: Incision of Overlying Tissue Once the anesthesia has taken effect, the surgeon makes an incision in the overlying tissue of the penis to access the plaque. This incision is carefully placed to minimize scarring and facilitate healing.
  • Step 3: Exposure of Plaque After the incision, the surgeon gently separates the tissue to expose the fibrous plaque. This step is crucial as it allows for a clear view of the plaque and surrounding structures.
  • Step 4: Plaque Expansion or Excision The surgeon then has the option to either expand the plaque by making several linear cuts or to excise it completely. The choice between these methods depends on the size and location of the plaque, as well as the surgeon's assessment of the best approach for the patient.
  • Step 5: Graft Placement (if necessary) If the excision of the plaque creates a significant defect, the surgeon may choose to cover the area with a graft. This graft can be made from the patient's own skin, a vein, or synthetic material, depending on the specific needs of the patient and the extent of the excision.
  • Step 6: Closure of Incision Finally, the surgeon closes the incision with sutures, ensuring that the tissue is properly aligned for optimal healing. The closure technique may vary based on the extent of the procedure and the surgeon's preference.

3. Post-Procedure

After the excision of penile plaque, patients are typically monitored for a short period to ensure there are no immediate complications. Post-procedure care may include instructions on managing pain, caring for the surgical site, and avoiding sexual activity for a specified period to allow for proper healing. Patients may also be advised to follow up with their healthcare provider to monitor recovery and assess the success of the procedure. It is important for patients to adhere to all post-operative instructions to minimize the risk of infection and promote optimal healing.

Short Descr TREATMENT OF PENIS LESION
Medium Descr EXCISION OF PENILE PLAQUE
Long Descr Excision of penile plaque (Peyronie disease);
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 2 - Payment restriction for assistants at surgery does not apply to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P5E - Ambulatory procedures - other
MUE 1
CCS Clinical Classification 118 - Other OR therapeutic procedures, male genital
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
80 Assistant surgeon: surgical assistant services may be identified by adding modifier 80 to the usual procedure number(s).
82 Assistant surgeon (when qualified resident surgeon not available): the unavailability of a qualified resident surgeon is a prerequisite for use of modifier 82 appended to the usual procedure code number(s).
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
GC This service has been performed in part by a resident under the direction of a teaching physician
XE Separate encounter, a service that is distinct because it occurred during a separate encounter
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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2010-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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